English

Critical Transitions In a Model of a Genetic Regulatory System

Chaotic Dynamics 2014-03-13 v2 Computational Engineering, Finance, and Science Computational Geometry Analysis of PDEs Genomics Quantitative Methods

Abstract

We consider a model for substrate-depletion oscillations in genetic systems, based on a stochastic differential equation with a slowly evolving external signal. We show the existence of critical transitions in the system. We apply two methods to numerically test the synthetic time series generated by the system for early indicators of critical transitions: a detrended fluctuation analysis method, and a novel method based on topological data analysis (persistence diagrams).

Keywords

Cite

@article{arxiv.1309.7919,
  title  = {Critical Transitions In a Model of a Genetic Regulatory System},
  author = {Jesse Berwald and Marian Gidea},
  journal= {arXiv preprint arXiv:1309.7919},
  year   = {2014}
}

Comments

19 pages, 8 figures