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Fluorescence recovery after photobleaching (FRAP) measurements offer an important tool for analyzing diffusion and binding processes. Confocal scanning laser microscopes that are used in FRAP experiments bleach regions with a radially…

Subcellular Processes · Quantitative Biology 2009-03-09 George D Tsibidis

Remodelling is defined as an evolution of microstructure or variations in the configuration of the underlying manifold. The manner in which a biological tissue and its subsystems remodel their structure is treated in a continuum mechanical…

Tissues and Organs · Quantitative Biology 2009-11-11 K. Garikipati , J. E. Olberding , E. M. Arruda , K. Grosh , H. Narayanan , S. Calve

We adapt the resonant state expansion to optical fibers such as capillary and photonic crystal fibers. As a key requirement of the resonant state expansion and any related perturbative approach, we derive the correct analytical…

Optics · Physics 2018-08-29 S. Upendar , I. Allayarov , M. A. Schmidt , T. Weiss

Knowledge of molecular structure is paramount in understanding, and ultimately influencing, chemical reactivity. For nearly a century, diffractive imaging has been used to identify the structures of many biologically-relevant gas-phase…

Chemical Physics · Physics 2020-03-09 Kasra Amini , Jens Biegert

Two-photon (2P) microscopy is a powerful technique for deep-tissue fluorescence imaging; however, tissue scattering limits its effectiveness for depth imaging using conventional approaches. Despite typical strategies having been put forward…

Optics · Physics 2025-05-21 Lei Zhu , Bernhard Rauer , Hilton B. De Aguiar , Sylvain Gigan

Optical spectroscopy is an important and widely used technique, for instance, to characterize new materials and to identify unknown compounds. Spectra are typically reported as a function of the wavelength of light, yet the information…

Optics · Physics 2026-05-06 Erik F. Woering , Richard Hildner

The aim of this article is to present a developed method that decomposes the autofluorescence spectrum into the spectra of naturally occurring biochemical components of biotissue. It requires knowledge of detailed spectrum behaviour of…

Biomolecules · Quantitative Biology 2007-05-23 V. Gavryushin

This paper proposes an unsupervised anomaly detection technique for image-based plant disease diagnosis. The construction of large and publicly available datasets containing labeled images of healthy and diseased crop plants led to growing…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Ryoya Katafuchi , Terumasa Tokunaga

Self-assembly is a phenomenon observed in nature at all scales where autonomous entities build complex structures, without external influences nor centralised master plan. Modelling such entities and programming correct interactions among…

Computational Complexity · Computer Science 2013-09-26 German Terrazas , Hector Zenil , Natalio Krasnogor

The multifarious internal workings of organisms are difficult to reconcile with a single feature defining a state of being alive. Indeed, definitions of life rely on emergent properties (growth, capacity to evolve, agency) only symptomatic…

Other Quantitative Biology · Quantitative Biology 2023-08-16 Simon Pierce

Pump-probe microscopy of melanin in tumors has been proposed to improve diagnosis of malignant melanoma, based on the hypothesis that aggressive cancers disaggregate melanin structure. However, measured signals of melanin are complex…

We study an inverse problem for Light Sheet Fluorescence Microscopy (LSFM), where the density of fluorescent molecules needs to be reconstructed. Our first step is to present a mathematical model to describe the measurements obtained by an…

Analysis of PDEs · Mathematics 2020-08-26 Evelyn Cueva , Matias Courdurier , Axel Osses , Victor Castañeda , Benjamin Palacios , Steffen Härtel

We derive the statistical limit of the spectral autocorrelation function and of the survival probability for the indirect photodissociation of molecules in the regime of non-overlapping resonances. The results are derived in the framework…

chao-dyn · Physics 2016-09-28 Y. Alhassid , Yan V. Fyodorov

Antibiotics such as the quinolones and fluoroquinolones kill bacterial pathogens ultimately through DNA damage. They target the essential type IIA topoisomerases in bacteria by stabilising the normally transient double strand break state…

Biomolecules · Quantitative Biology 2016-05-26 Helen Miller , Adam J. M. Wollman , Mark C. Leake

Image restoration is the task of recovering a clean image from a degraded version. In most cases, the degradation is spatially varying, and it requires the restoration network to both localize and restore the affected regions. In this…

Image and Video Processing · Electrical Eng. & Systems 2022-01-04 Maitreya Suin , Kuldeep Purohit , A. N. Rajagopalan

A fundamental issue that limits the efficiency of many photoelectrochemical systems is that the photon absorption length is typically much longer than the electron diffusion length. Various photon management schemes have been developed to…

The study of immune system aging, i.e. immunosenescence, is a relatively new research topic. It deals with understanding the processes of immunodegradation that indicate signs of functionality loss possibly leading to death. Even though it…

Artificial Intelligence · Computer Science 2010-07-05 Grazziela P. Figueredo , Uwe Aickelin , Amanda Whitbrook

Although the amino acid tyrosine is among the main building blocks of life, its photochemistry is not fully understood. Traditional theoretical simulations are neither accurate enough, nor computationally efficient to provide the missing…

We present the first measurements and simulations of recombination fluorescence in ultracold neutral plasmas. In contrast with previous work, experiment and simulation are in significant disagreement. Comparison with a recombination model…

Atomic Physics · Physics 2009-11-13 S. D. Bergeson , F. Robicheaux

Quantum states inevitably decay with time into a probabilistic mixture of classical states, due to their interaction with the environment and measurement instrumentation. We present the first measurement of the decoherence dynamics of…

Mesoscale and Nanoscale Physics · Physics 2015-05-14 H. Wang , M. Hofheinz , M. Ansmann , R. C. Bialczak , Erik Lucero , M. Neeley , A. D. O'Connell , D. Sank , M. Weides , J. Wenner , A. N. Cleland , John M. Martinis
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