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High-content image-based assays have fueled significant discoveries in the life sciences in the past decade (2013-2023), including novel insights into disease etiology, mechanism of action, new therapeutics, and toxicology predictions.…

Subcellular Processes · Quantitative Biology 2024-05-07 Srijit Seal , Maria-Anna Trapotsi , Ola Spjuth , Shantanu Singh , Jordi Carreras-Puigvert , Nigel Greene , Andreas Bender , Anne E. Carpenter

The decay of field-free rotational dynamics is experimentally studied in two complementary methods: laser-induced molecular alignment and terahertz-field-induced molecular orientation. Comparison between the decay rates of different…

Chemical Physics · Physics 2017-07-26 Ran Damari , Dina Kardash , Sharly Fleischer

Drug repositioning is an attractive cost-efficient strategy for the development of treatments for human diseases. Here, we propose an interpretable model that learns disease self-representations for drug repositioning. Our…

Photochromic materials enable dynamic optical modulation through reversible transitions between distinct absorption states, with broad potential for smart windows, adaptive optics, and reconfigurable photonic devices. Micron-scale…

Computational Physics · Physics 2026-02-19 Bahrem Serhat Danis , Amin Tabatabaei Mohseni , Smagul Karazhanov , Esra Zayim

Antibodies are essential proteins responsible for immune responses in organisms, capable of specifically recognizing antigen molecules of pathogens. Recent advances in generative models have significantly enhanced rational antibody design.…

Artificial Intelligence · Computer Science 2025-11-10 Zichen Wang , Yaokun Ji , Jianing Tian , Shuangjia Zheng

Medical imaging is an invaluable resource in medicine as it enables to peer inside the human body and provides scientists and physicians with a wealth of information indispensable for understanding, modelling, diagnosis, and treatment of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Hanene Ben Yedder , Ben Cardoen , Ghassan Hamarneh

The colorful appearance of a physical painting is determined by the distribution of paint pigments across the canvas, which we model as a per-pixel mixture of a small number of pigments with multispectral absorption and scattering…

Graphics · Computer Science 2018-07-23 Jianchao Tan , Stephen DiVerdi , Jingwan Lu , Yotam Gingold

We introduce a framework for recovering an image from its rotationally and translationally invariant features based on autocorrelation analysis. This work is an instance of the multi-target detection statistical model, which is mainly used…

Image and Video Processing · Electrical Eng. & Systems 2022-03-03 Nicholas F. Marshall , Ti-Yen Lan , Tamir Bendory , Amit Singer

A defining feature of living matter is the ability to harness energy to self-organize multiscale structures whose functions are facilitated by irreversible nonequilibrium dynamics. While progress has been made in elucidating the underlying…

Ground-based solar image restoration is a computationally expensive procedure that involves nonlinear optimization techniques. The presence of atmospheric turbulence produces perturbations in individual images that make it necessary to…

Instrumentation and Methods for Astrophysics · Physics 2023-07-26 A. Asensio Ramos , S. Esteban Pozuelo , C. Kuckein

A recently developed energy-dependent frame transformation theory that incorporates both ionization and dissociation channels of the H$_2$ molecule, is extended to treat the ungerade states that occur both in dissociative recombination and…

Chemical Physics · Physics 2025-11-21 Dávid Hvizdoš , Roman Čurík , Chris H. Greene

This paper is concerned with two rather basic phenomena: the incoherent fluorescence spectrum of an atom driven by an intense laser field and the coupling of the atom to the (empty) modes of the radiation field. The sum of the many-photon…

Quantum Physics · Physics 2007-05-23 Ulrich D. Jentschura , Joerg Evers , Christoph H. Keitel

The reproduction of a living cell requires a repeatable set of chemical events to be properly coordinated. Such events define a replication cycle, coupling the growth and shape change of the cell membrane with internal metabolic reactions.…

Cell Behavior · Quantitative Biology 2007-05-23 J. Macia , R. V. Sole

In the end of the second decade of 20th century, Warburg showed how cancer cells present a fermentative respiration process, related to a metabolic injury. Here, we develop an analysis of the cell process based on its heat outflow, in order…

Cell Behavior · Quantitative Biology 2021-07-27 Umberto Lucia , Giulia Grisolia

In the last two decades about a dozen methods were invented which derive, from a series of composite spectra over the orbit, the spectra of individual components in binary and multiple systems. Reconstructed spectra can then be analyzed…

Solar and Stellar Astrophysics · Physics 2009-09-18 K. Pavlovski , H. Hensberge

Organic molecules have recently gained attention as novel sources of single photons. We present a joint experiment--theory analysis of the temperature-dependent emission spectra, zero-phonon linewidth, and second-order correlation function…

We study the self-healing process of materials with embedded "glue"-carrying cells, in the regime of the onset of the initial fatigue. Three-dimensional numerical simulations within the percolation-model approach are reported. The main…

Materials Science · Physics 2010-10-12 A. Dementsov , V. Privman

Most existing non-blind restoration methods are based on the assumption that a precise degradation model is known. As the degradation process can only be partially known or inaccurately modeled, images may not be well restored. Rain streak…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Dongwei Ren , Wangmeng Zuo , David Zhang , Lei Zhang , Ming-Hsuan Yang

Wavefront shaping systems aim to image deep into scattering tissue by reshaping incoming and outgoing light to correct aberrations caused by tissue inhomogeneity However, the desired modulation depends on the unknown tissue structure and…

Optics · Physics 2026-01-14 Sagi Monin , Marina Alterman , Anat Levin

Assembly of protein complexes like virus shells, the centriole, the nuclear pore complex or the actin cytoskeleton is strongly determined by their spatial structure. Moreover it is becoming increasingly clear that the reversible nature of…

Subcellular Processes · Quantitative Biology 2014-05-13 Heinrich C. R. Klein , Ulrich S. Schwarz