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Differential privacy is a popular privacy-enhancing technology that has been deployed both in industry and government agencies. Unfortunately, existing explanations of differential privacy fail to set accurate privacy expectations for data…

Cryptography and Security · Computer Science 2025-09-29 Mary Anne Smart , Priyanka Nanayakkara , Rachel Cummings , Gabriel Kaptchuk , Elissa Redmiles

Sharing health and behavioral data raises significant privacy concerns, as conventional de-identification methods are susceptible to privacy attacks. Differential Privacy (DP) provides formal guarantees against re-identification risks, but…

Formal disclosure avoidance techniques are necessary to ensure that published data can not be used to identify information about individuals. The addition of statistical noise to unpublished data can be implemented to achieve differential…

Methodology · Statistics 2024-06-10 Ryan Janicki , Scott H. Holan , Kyle M. Irimata , James Livsey , Andrew Raim

Genome-wide association studies (GWAS) are used to identify relationships between genetic variations and specific traits. When applied to high-dimensional medical imaging data, a key step is to extract lower-dimensional, yet informative…

Quantitative Methods · Quantitative Biology 2023-09-28 Yaochen Xie , Ziqian Xie , Sheikh Muhammad Saiful Islam , Degui Zhi , Shuiwang Ji

While significant progress has been made in conventional fairness-aware machine learning (ML) and differentially private ML (DPML), the fairness of privacy protection across groups remains underexplored. Existing studies have proposed…

Machine Learning · Computer Science 2025-11-18 Zhi Yang , Changwu Huang , Ke Tang , Xin Yao

While previous works on privacy-preserving serial data publishing consider the scenario where sensitive values may persist over multiple data releases, we find that no previous work has sufficient protection provided for sensitive values…

Databases · Computer Science 2009-03-05 Raymond Chi-Wing Wong , Ada Wai-Chee Fu , Jia Liu , Ke Wang , Yabo Xu

A computationally simple genome-wide association study (GWAS) algorithm for estimating the main and epistatic effects of markers or single nucleotide polymorphisms (SNPs) is proposed. It is based on the intuitive assumption that changes of…

Quantitative Methods · Quantitative Biology 2017-08-08 Lev V. Utkin , Irina L. Utkina

Various privacy-preserving frameworks that respect the individual's privacy in the analysis of data have been developed in recent years. However, available model classes such as simple statistics or generalized linear models lack the…

Machine Learning · Statistics 2023-03-13 Daniel Schalk , Bernd Bischl , David Rügamer

The authors discuss their experience applying differential privacy with a complex data set with the goal of enabling standard approaches to statistical data analysis. They highlight lessons learned and roadblocks encountered, distilling…

Cryptography and Security · Computer Science 2023-10-02 Joshua Snoke , Claire McKay Bowen , Aaron R. Williams , Andrés F. Barrientos

Statistical agencies rely on sampling techniques to collect socio-demographic data crucial for policy-making and resource allocation. This paper shows that surveys of important societal relevance introduce sampling errors that unevenly…

Cryptography and Security · Computer Science 2025-01-22 Joonhyuk Ko , Juba Ziani , Saswat Das , Matt Williams , Ferdinando Fioretto

In recent years, Whole Genome Sequencing (WGS) evolved from a futuristic-sounding research project to an increasingly affordable technology for determining complete genome sequences of complex organisms, including humans. This prompts a…

Cryptography and Security · Computer Science 2015-02-17 Erman Ayday , Emiliano De Cristofaro , Jean-Pierre Hubaux , Gene Tsudik

Datasets containing sensitive information are often sequentially analyzed by many algorithms. This raises a fundamental question in differential privacy regarding how the overall privacy bound degrades under composition. To address this…

Machine Learning · Statistics 2020-03-26 Qinqing Zheng , Jinshuo Dong , Qi Long , Weijie J. Su

Big data is a term used for a very large data sets that have many difficulties in storing and processing the data. Analysis this much amount of data will lead to information loss. The main goal of this paper is to share data in a way that…

Cryptography and Security · Computer Science 2018-08-14 Jalpesh Vasa , Panthini Modi

In an era where external data and computational capabilities far exceed statistical agencies' own resources and capabilities, they face the renewed challenge of protecting the confidentiality of underlying microdata when publishing…

Applications · Statistics 2022-12-29 John M Abowd , Michael B Hawes

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…

Cryptography and Security · Computer Science 2022-02-11 Sara Jafarbeiki , Raj Gaire , Amin Sakzad , Shabnam Kasra Kermanshahi , Ron Steinfeld

Data is used widely by service providers as input to inference systems to perform decision making for authorized tasks. The raw data however allows a service provider to infer other sensitive information it has not been authorized for. We…

Cryptography and Security · Computer Science 2020-10-26 Chong Xiao Wang , Wee Peng Tay

Differential privacy has emerged as a gold standard in privacy-preserving data analysis. A popular variant is local differential privacy, where the data holder is the trusted curator. A major barrier, however, towards a wider adoption of…

Cryptography and Security · Computer Science 2019-06-18 Joseph Geumlek , Kamalika Chaudhuri

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Differential privacy is becoming a gold standard for privacy research; it offers a guaranteed bound on loss of privacy due to release of query results, even under worst-case assumptions. The theory of differential privacy is an active…

An important task of human genetics studies is to accurately predict disease risks in individuals based on genetic markers, which allows for identifying individuals at high disease risks, and facilitating their disease treatment and…

Genomics · Quantitative Biology 2013-08-20 Cong Li , Can Yang , Joel Gelernter , Hongyu Zhao