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Multi-trait genome-wide association studies (GWAS) use multi-variate statistical methods to identify associations between genetic variants and multiple correlated traits simultaneously, and have higher statistical power than independent…

Genomics · Quantitative Biology 2022-02-10 Muhammad Ammar Malik , Adriaan-Alexander Ludl , Tom Michoel

There are many existing differentially private algorithms for releasing histograms, i.e. counts with corresponding labels, in various settings. Our focus in this survey is to revisit some of the existing differentially private algorithms…

Cryptography and Security · Computer Science 2024-08-05 Ryan Rogers

Open data plays a fundamental role in the 21th century by stimulating economic growth and by enabling more transparent and inclusive societies. However, it is always difficult to create new high-quality datasets with the required privacy…

Cryptography and Security · Computer Science 2019-03-07 Lorenzo Frigerio , Anderson Santana de Oliveira , Laurent Gomez , Patrick Duverger

Ratio statistics--such as relative risk and odds ratios--play a central role in hypothesis testing, model evaluation, and decision-making across many areas of machine learning, including causal inference and fairness analysis. However,…

Machine Learning · Statistics 2025-05-28 Tomer Shoham , Katrina Ligettt

We propose a novel federated learning paradigm to model data variability among heterogeneous clients in multi-centric studies. Our method is expressed through a hierarchical Bayesian latent variable model, where client-specific parameters…

Machine Learning · Computer Science 2023-06-29 Irene Balelli , Santiago Silva , Marco Lorenzi

We introduce a deep learning framework able to deal with strong privacy constraints. Based on collaborative learning, differential privacy and homomorphic encryption, the proposed approach advances state-of-the-art of private deep learning…

Cryptography and Security · Computer Science 2021-03-29 Arnaud Grivet Sébert , Rafael Pinot , Martin Zuber , Cédric Gouy-Pailler , Renaud Sirdey

Confidence intervals are a fundamental tool for quantifying the uncertainty of parameters of interest. With the increase of data privacy awareness, developing a private version of confidence intervals has gained growing attention from both…

Methodology · Statistics 2024-04-12 Shurong Lin , Mark Bun , Marco Gaboardi , Eric D. Kolaczyk , Adam Smith

Healthcare data contains sensitive information, and it is challenging to persuade healthcare data owners to share their information for research purposes without any privacy assurance. The proposed hybrid medical data privacy protection…

Cryptography and Security · Computer Science 2022-05-10 Judy X Yang , Hui Tian , Alan Wee-Chung Liew , Ernest Foo

The rise of powerful AI models, more formally $\textit{General-Purpose AI Systems}$ (GPAIS), has led to impressive leaps in performance across a wide range of tasks. At the same time, researchers and practitioners alike have raised a number…

Computers and Society · Computer Science 2024-07-03 Stephen Meisenbacher , Alexandra Klymenko , Patrick Gage Kelley , Sai Teja Peddinti , Kurt Thomas , Florian Matthes

The application of graph analytics to various domains has yielded tremendous societal and economical benefits in recent years. However, the increasingly widespread adoption of graph analytics comes with a commensurate increase in the need…

Cryptography and Security · Computer Science 2022-06-07 Yang Li , Michael Purcell , Thierry Rakotoarivelo , David Smith , Thilina Ranbaduge , Kee Siong Ng

While pursuing better utility by discovering knowledge from the data, individual's privacy may be compromised during an analysis. To that end, differential privacy has been widely recognized as the state-of-the-art privacy notion. By…

Cryptography and Security · Computer Science 2022-09-07 Meisam Mohammady

In some socio-economic surveys, data are collected on sensitive or stigmatizing issues such as tax evasion, criminal conviction, drug use, etc. In such surveys, direct questioning of respondents is not of much use and the randomized…

Statistics Theory · Mathematics 2013-03-22 Mausumi Bose

Machine Learning on Big Data gets more and more attention in various fields. Even so privacy-preserving techniques become more important, even necessary due to legal regulations such as the General Data Protection Regulation (GDPR). On the…

Cryptography and Security · Computer Science 2022-01-28 Jasmin Zalonis , Frederik Armknecht , Björn Grohmann , Manuel Koch

With the development of big data and machine learning, privacy concerns have become increasingly critical, especially when handling heterogeneous datasets containing sensitive personal information. Differential privacy provides a rigorous…

Machine Learning · Statistics 2025-08-08 Ziliang Shen , Caixing Wang , Shaoli Wang , Yibo Yan

A key tool for building differentially private systems is adding Gaussian noise to the output of a function evaluated on a sensitive dataset. Unfortunately, using a continuous distribution presents several practical challenges. First and…

Data Structures and Algorithms · Computer Science 2024-11-19 Clément L. Canonne , Gautam Kamath , Thomas Steinke

This paper investigates the problem of forecasting multivariate aggregated human mobility while preserving the privacy of the individuals concerned. Differential privacy, a state-of-the-art formal notion, has been used as the privacy…

Machine Learning · Computer Science 2022-06-06 Héber H. Arcolezi , Jean-François Couchot , Denis Renaud , Bechara Al Bouna , Xiaokui Xiao

Unsupervised domain adaptation (UDA) generally aligns the unlabeled target domain data to the distribution of the source domain to mitigate the distribution shift problem. The standard UDA requires sharing the source data with the target,…

Computation and Language · Computer Science 2022-01-20 Qiyuan An , Ruijiang Li , Lin Gu , Hao Zhang , Qingyu Chen , Zhiyong Lu , Fei Wang , Yingying Zhu

Sampling schemes are fundamental tools in statistics, survey design, and algorithm design. A fundamental result in differential privacy is that a differentially private mechanism run on a simple random sample of a population provides…

Methodology · Statistics 2023-06-23 Mark Bun , Jörg Drechsler , Marco Gaboardi , Audra McMillan , Jayshree Sarathy

Deep generative models open new avenues for simulating realistic genomic data while preserving privacy and addressing data accessibility constraints. While previous studies have primarily focused on generating gene expression or haplotype…

Genomics · Quantitative Biology 2025-08-14 Sihan Xie , Thierry Tribout , Didier Boichard , Blaise Hanczar , Julien Chiquet , Eric Barrey

We propose a practical methodology to protect a user's private data, when he wishes to publicly release data that is correlated with his private data, in the hope of getting some utility. Our approach relies on a general statistical…

Cryptography and Security · Computer Science 2015-10-28 Salman Salamatian , Amy Zhang , Flavio du Pin Calmon , Sandilya Bhamidipati , Nadia Fawaz , Branislav Kveton , Pedro Oliveira , Nina Taft