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Data stewards and analysts can promote transparent and trustworthy science and policy-making by facilitating assessments of the sensitivity of published results to alternate analysis choices. For example, researchers may want to assess…

Methodology · Statistics 2023-08-24 Chengxin Yang , Jerome P. Reiter

We are entering the era of ubiquitous genetic information for research, clinical care, and personal curiosity. Sharing these datasets is vital for rapid progress in understanding the genetic basis of human diseases. However, one growing…

Genomics · Quantitative Biology 2013-10-14 Yaniv Erlich , Arvind Narayanan

Data collected about individuals is regularly used to make decisions that impact those same individuals. We consider settings where sensitive personal data is used to decide who will receive resources or benefits. While it is well known…

Databases · Computer Science 2020-01-28 Satya Kuppam , Ryan Mckenna , David Pujol , Michael Hay , Ashwin Machanavajjhala , Gerome Miklau

We develop formal privacy mechanisms for releasing statistics from data with many outlying values, such as income data. These mechanisms ensure that a per-record differential privacy guarantee degrades slowly in the protected records'…

Cryptography and Security · Computer Science 2025-05-05 Brian Finley , Anthony M Caruso , Justin C Doty , Ashwin Machanavajjhala , Mikaela R Meyer , David Pujol , William Sexton , Zachary Terner

Recently introduced privacy legislation has aimed to restrict and control the amount of personal data published by companies and shared to third parties. Much of this real data is not only sensitive requiring anonymization, but also…

Databases · Computer Science 2020-07-20 Mostafa Milani , Yu Huang , Fei Chiang

Concern about how to aggregate sensitive user data without compromising individual privacy is a major barrier to greater availability of data. The model of differential privacy has emerged as an accepted model to release sensitive…

Databases · Computer Science 2017-10-03 Graham Cormode , Tejas Kulkarni , Divesh Srivastava

The introduction of data analytics into medicine has changed the nature of patient treatment. In this, patients are asked to disclose personal information such as genetic markers, lifestyle habits, and clinical history. This data is then…

Cryptography and Security · Computer Science 2017-10-17 Z. Berkay Celik , David Lopez-Paz , Patrick McDaniel

Modern society generates an incredible amount of data about individuals, and releasing summary statistics about this data in a manner that provably protects individual privacy would offer a valuable resource for researchers in many fields.…

Cryptography and Security · Computer Science 2018-02-21 Zachary Campbell , Andrew Bray , Anna Ritz , Adam Groce

Causal inference plays a crucial role in scientific research across multiple disciplines. Estimating causal effects, particularly the average treatment effect (ATE), from observational data has garnered significant attention. However,…

Cryptography and Security · Computer Science 2025-12-17 Quan Yuan , Xiaochen Li , Linkang Du , Min Chen , Mingyang Sun , Yunjun Gao , Shibo He , Jiming Chen , Zhikun Zhang

Decentralized optimization is gaining increased traction due to its widespread applications in large-scale machine learning and multi-agent systems. The same mechanism that enables its success, i.e., information sharing among participating…

Optimization and Control · Mathematics 2024-02-07 Yongqiang Wang , Angelia Nedic

Drug development is a very costly and lengthy process, while repositioned or repurposed drugs could be brought into clinical practice within a shorter time-frame and at a much reduced cost. The past decade has observed a massive growth in…

Genomics · Quantitative Biology 2019-11-14 Alexandria Lau , Hon-Cheong So

Online collaborative medical prediction platforms offer convenience and real-time feedback by leveraging massive electronic health records. However, growing concerns about privacy and low prediction quality can deter patient participation…

Machine Learning · Computer Science 2025-07-16 Shao-Bo Lin , Xiaotong Liu , Yao Wang

Genome-Wide Association Studies (GWAS) help identify genetic variations in people with diseases such as Parkinson's disease (PD), which are less common in those without the disease. Thus, GWAS data can be used to identify genetic variations…

Genomics · Quantitative Biology 2023-04-07 Ali Amelia , Lourdes Pena-Castillo , Hamid Usefi

Differential privacy comes equipped with multiple analytical tools for the design of private data analyses. One important tool is the so-called "privacy amplification by subsampling" principle, which ensures that a differentially private…

Machine Learning · Computer Science 2018-11-26 Borja Balle , Gilles Barthe , Marco Gaboardi

Gaussian processes (GPs) are non-parametric Bayesian models that are widely used for diverse prediction tasks. Previous work in adding strong privacy protection to GPs via differential privacy (DP) has been limited to protecting only the…

Machine Learning · Computer Science 2021-11-12 Antti Honkela , Laila Melkas

Differential privacy is widely considered the formal privacy for privacy-preserving data analysis due to its robust and rigorous guarantees, with increasingly broad adoption in public services, academia, and industry. Despite originating in…

Statistics Theory · Mathematics 2024-12-05 Weijie J. Su

Differential privacy guarantees allow the results of a statistical analysis involving sensitive data to be released without compromising the privacy of any individual taking part. Achieving such guarantees generally requires the injection…

Machine Learning · Statistics 2023-10-31 Jack Jewson , Sahra Ghalebikesabi , Chris Holmes

In this paper, we propose a novel Heterogeneous Gaussian Mechanism (HGM) to preserve differential privacy in deep neural networks, with provable robustness against adversarial examples. We first relax the constraint of the privacy budget in…

Cryptography and Security · Computer Science 2019-06-05 NhatHai Phan , Minh Vu , Yang Liu , Ruoming Jin , Dejing Dou , Xintao Wu , My T. Thai

The wide-spread availability of rich data has fueled the growth of machine learning applications in numerous domains. However, growth in domains with highly-sensitive data (e.g., medical) is largely hindered as the private nature of data…

Machine Learning · Computer Science 2021-03-16 Dingfan Chen , Tribhuvanesh Orekondy , Mario Fritz

This work studies formal utility and privacy guarantees for a simple multiplicative database transformation, where the data are compressed by a random linear or affine transformation, reducing the number of data records substantially, while…

Machine Learning · Statistics 2009-01-13 Shuheng Zhou , Katrina Ligett , Larry Wasserman
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