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Ever since deoxyribonucleic acid (DNA) was considered as a next-generation data-storage medium, lots of research efforts have been made to correct errors occurred during the synthesis, storage, and sequencing processes using error…

Information Theory · Computer Science 2023-06-14 Jaeho Jeong , Hosung Park , Hee-Youl Kwak , Jong-Seon No , Hahyeon Jeon , Jeong Wook Lee , Jae-Won Kim

Image translation with convolutional autoencoders has recently been used as an approach to multimodal change detection in bitemporal satellite images. A main challenge is the alignment of the code spaces by reducing the contribution of…

Computer Vision and Pattern Recognition · Computer Science 2020-04-16 Luigi T. Luppino , Mads A. Hansen , Michael Kampffmeyer , Filippo M. Bianchi , Gabriele Moser , Robert Jenssen , Stian N. Anfinsen

This paper presents a novel optical processing approach for exploring genome sequences built upon optical correlator for global alignment and extended DV-curve method for local alignment. To overcome the problem of traditional DV-curve…

Quantitative Methods · Quantitative Biology 2018-01-03 Ehsan Maleki , Hossein Babashah , Somayyeh Koohi , Zahra Kavehvash

Composite DNA is a recent method to increase the base alphabet size in DNA-based data storage.This paper models synthesizing and sequencing of composite DNA and introduces coding techniques to correct substitutions, losses of entire…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Omer Sabary , Antonia Wachter-Zeh , Eitan Yaakobi

Sequences of nucleotides (for DNA and RNA) or amino acids (for proteins) are central objects in biology. Among the most important computational problems is that of sequence alignment, i.e. arranging sequences from different organisms in…

Quantitative Methods · Quantitative Biology 2020-12-08 Anna Paola Muntoni , Andrea Pagnani , Martin Weigt , Francesco Zamponi

Encoding information in combinations of pre-synthesised deoxyribonucleic acid (DNA) strands (referred to as motifs) is an interesting approach to DNA storage that could potentially circumvent the prohibitive costs of…

Information Theory · Computer Science 2024-12-05 Roman Sokolovskii , Parv Agarwal , Luis Alberto Croquevielle , Zijian Zhou , Thomas Heinis

High read depth can be used to assemble short sequence repeats. The existing genome assemblers fail in repetitive regions of longer than average read. I propose a new algorithm for a DNA assembly which uses the relative frequency of reads…

Genomics · Quantitative Biology 2015-01-08 Robert M. Nowak

Optical two-dimensional (2D) coherent spectroscopy excels in studying coupling and dynamics in complex systems. The dynamical information can be learned from lineshape analysis to extract the corresponding linewidth. However, it is usually…

Optics · Physics 2020-06-24 Srikanth Namuduri , Michael Titze , Shekhar Bhansali , Hebin Li

Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Ning Zhang , Susan Francis , Rayaz Malik , Xin Chen

When an individual's DNA is sequenced, sensitive medical information becomes available to the sequencing laboratory. A recently proposed way to hide an individual's genetic information is to mix in DNA samples of other individuals. We…

Information Theory · Computer Science 2024-11-05 Kayvon Mazooji , Roy Dong , Ilan Shomorony

Motion blur is a known issue in photography, as it limits the exposure time while capturing moving objects. Extensive research has been carried to compensate for it. In this work, a computational imaging approach for motion deblurring is…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Shay Elmalem , Raja Giryes , Emanuel Marom

Persistent homology provides information about the lifetime of homology classes along a filtration of cell complexes. Persistence barcode is a graphical representation of such information. A filtration might be determined by time in a set…

Computer Vision and Pattern Recognition · Computer Science 2018-01-04 Rocio Gonzalez-Diaz , Maria-Jose Jimenez , Belen Medrano

Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit. Relying on either four primitive bases or independently…

Genomics · Quantitative Biology 2025-11-20 Siyuan Li , Kai Yu , Anna Wang , Zicheng Liu , Chang Yu , Jingbo Zhou , Qirong Yang , Yucheng Guo , Xiaoming Zhang , Stan Z. Li

Developmental transcriptional networks in plants and animals operate in both space and time. To understand these transcriptional networks it is essential to obtain whole-genome expression data at high spatiotemporal resolution. Substantial…

Genomics · Quantitative Biology 2009-03-25 Dustin A. Cartwright , Siobhan M. Brady , David A. Orlando , Bernd Sturmfels , Philip N. Benfey

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

Spatial transcriptomics is a technology that captures gene expression levels at different spatial locations, widely used in tumor microenvironment analysis and molecular profiling of histopathology, providing valuable insights into…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Junzhuo Liu , Markus Eckstein , Zhixiang Wang , Friedrich Feuerhake , Dorit Merhof

Recently, self-supervised learning (SSL) methods have been used in pre-training the segmentation models for 2D and 3D medical images. Most of these methods are based on reconstruction, contrastive learning and consistency regularization.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Haofeng Li , Yiming Ouyang , Xiang Wan

Dynamic magnetic resonance imaging (MRI) plays an indispensable role in cardiac diagnosis. To enable fast imaging, the k-space data can be undersampled but the image reconstruction poses a great challenge of high-dimensional processing.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Zi Wang , Min Xiao , Yirong Zhou , Chengyan Wang , Naiming Wu , Yi Li , Yiwen Gong , Shufu Chang , Yinyin Chen , Liuhong Zhu , Jianjun Zhou , Congbo Cai , He Wang , Di Guo , Guang Yang , Xiaobo Qu

Single-cell RNA-sequencing technologies may provide valuable insights to the understanding of the composition of different cell types and their functions within a tissue. Recent technologies such as spatial transcriptomics, enable the…

Applications · Statistics 2023-05-16 Arhit Chakrabarti , Yang Ni , Bani K. Mallick

In the current era, DeoxyriboNucleic Acid (DNA) based data storage emerges as an intriguing approach, garnering substantial academic interest and investigation. This paper introduces a novel deep joint source-channel coding (DJSCC) scheme…

Emerging Technologies · Computer Science 2023-11-03 Wenfeng Wu , Luping Xiang , Qiang Liu , Kun Yang