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Deterministic and stochastic Boolean network models are build for the dynamics of negative feedback loops of the p53 pathways. It is shown that the main function of the negative feedback in the p53 pathways is to keep p53 at a low steady…

Molecular Networks · Quantitative Biology 2009-04-16 Hao Ge , Min Qian

We study the dynamics of randomly connected networks composed of binary Boolean elements and those composed of binary majority vote elements. We elucidate their differences in both sparsely and densely connected cases. The quickness of…

Disordered Systems and Neural Networks · Physics 2013-03-06 Shun-ichi Amari , Hiroyasu Ando , Taro Toyoizumi , Naoki Masuda

Network remodeling, or adaptation, in the presence of periodically driven forcings has hereto remained largely unexplored, despite the fact that a broad class of biological transport networks, e.g. animal vasculature, depends on periodic…

Adaptation and Self-Organizing Systems · Physics 2026-01-01 Purba Chatterjee , Eleni Katifori

Most models of complex systems have been homogeneous, i.e., all elements have the same properties (spatial, temporal, structural, functional). However, most natural systems are heterogeneous: few elements are more relevant, larger,…

Adaptation and Self-Organizing Systems · Physics 2025-12-22 Amahury Jafet López-Díaz , Fernanda Sánchez-Puig , Carlos Gershenson

In this article, we design the distributed pinning controllers to globally stabilize a Boolean network (BN), specially a sparsely connected large-scale one, towards a preassigned subset of state space through the node-to-node message…

Systems and Control · Electrical Eng. & Systems 2022-03-16 Shiyong Zhu , Jianquan Lu , Liangjie Sun , Jinde Cao

The asynchronous dynamics associated with a Boolean network $f : \{0,1\}^n \to \{0,1\}^n$ is a finite deterministic automaton considered in many applications. The set of states is $\{0,1\}^n$, the alphabet is $[n]$, and the action of letter…

Combinatorics · Mathematics 2018-04-06 Maximilien Gadouleau , Adrien Richard

Many natural systems are organized as networks, in which the nodes (be they cells, individuals or populations) interact in a time-dependent fashion. The dynamic behavior of these networks depends on how these nodes are connected, which can…

Neurons and Cognition · Quantitative Biology 2015-06-22 Anca Radulescu , Sergio Verduzco-Flores

The process of training an artificial neural network involves iteratively adapting its parameters so as to minimize the error of the network's prediction, when confronted with a learning task. This iterative change can be naturally…

Machine Learning · Computer Science 2024-04-10 Kaloyan Danovski , Miguel C. Soriano , Lucas Lacasa

We performed a numerical study on random Boolean networks with power-law rank outdegree distributions to find local structural cause for the emergence of high or low degree of coherence in binary state variables. The degree of randomness…

Cellular Automata and Lattice Gases · Physics 2007-07-02 Chikoo Oosawa , Kazuhiro Takemoto , Shogo Matsumoto , Michael A. Savageau

We study transient sequential dynamics of evolving dynamical networks, i.e., those having active nodes and links and activity-dependent topology. We show that such networks can generate sequences of metastable cluster states where each…

Chaotic Dynamics · Physics 2014-12-01 Oleg V. Maslennikov , Vladimir I. Nekorkin

Methods of modeling cellular regulatory networks as diverse as differential equations and Boolean networks co-exist, however, without any closer correspondence to each other. With the example system of the fission yeast cell cycle control…

Molecular Networks · Quantitative Biology 2015-03-13 Maria Davidich , Stefan Bornholdt

Dynamic Bayesian networks (DBNs) are a widely used framework for modeling systems whose probabilistic structure evolves over time. Standard inference methods focus on local conditional distributions and can miss larger-scale patterns in how…

Algebraic Topology · Mathematics 2026-05-13 Will Bales , Carmen Rovi

The permutation binary neural networks are characterized by global permutation connections and local binary connections. Although the parameter space is not large, the networks exhibit various binary periodic orbits. Since analysis of all…

Dynamical Systems · Mathematics 2023-01-10 Mikito Onuki , Kento Saka , Toshimichi Saito

We evaluate the probability that a Boolean network returns to an attractor after perturbing h nodes. We find that the return probability as function of h can display a variety of different behaviours, which yields insights into the…

Statistical Mechanics · Physics 2010-07-02 C. Fretter , B. Drossel

Finite dynamical systems (e.g. Boolean networks and logical models) have been used in modeling biological systems to focus attention on the qualitative features of the system, such as the wiring diagram. Since the analysis of such systems…

Molecular Networks · Quantitative Biology 2012-11-27 Alan Veliz-Cuba , Kristina Buschur , Rose Hamershock , Ariel Kniss , Esther Wolff , Reinhard Laubenbacher

Discrete models have a long tradition in engineering, including finite state machines, Boolean networks, Petri nets, and agent-based models. Of particular importance is the question of how the model structure constrains its dynamics. This…

Molecular Networks · Quantitative Biology 2011-08-02 Reinhard Laubenbacher , David Murrugarra , Alan Veliz-Cuba

Boolean Networks and their dynamics are of great interest as abstract modeling schemes in various disciplines, ranging from biology to computer science. Whereas parallel update schemes have been studied extensively in past years, the level…

Statistical Mechanics · Physics 2007-07-19 Hamed Mahmoudi , Andrea Pagnani , Martin Weigt , Riccardo Zecchina

During the last few years an area of active research in the field of complex systems is that of their information storing and processing abilities. Common opinion has it that the most interesting beaviour of these systems is found ``at the…

adap-org · Physics 2007-05-23 Bartolo Luque , Antonio Ferrera

We are interested in fixed points in Boolean networks, {\em i.e.} functions $f$ from $\{0,1\}^n$ to itself. We define the subnetworks of $f$ as the restrictions of $f$ to the subcubes of $\{0,1\}^n$, and we characterizes a class…

Discrete Mathematics · Computer Science 2014-12-05 Adrien Richard

A logical function can be used to characterizing a property of a state of Boolean network (BN), which is considered as an aggregation of states. To illustrate the dynamics of a set of logical functions, which characterize our concerned…

Systems and Control · Electrical Eng. & Systems 2021-04-20 Daizhan Cheng , Lijun Zhang , Dongyao Bi