Related papers: Abaqus/Standard-based quantification of human card…

Subject-specific modeling is a powerful tool in cardiovascular research, providing insights beyond the reach of current clinical diagnostics. Limitations in available clinical data require the incorporation of uncertainty into models to…

Cardiovascular diseases are among the leading causes of death globally. Cardiac left ventricle (LV) quantification is known to be one of the most important tasks for the identification and diagnosis of such pathologies. In this paper, we…

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

We present a novel approach to learn the formulae characterising the emergent behaviour of a dynamical system from system observations. At a high level, the approach starts by devising a statistical dynamical model of the system which…

Heart failure affects millions of people worldwide, significantly reducing quality of life and leading to high mortality rates. Despite extensive research, the relationship between heart failure and mortality rates among ICU patients is not…

Recent research is revealing how cognitive processes are supported by a complex interplay between the brain and the rest of the body, which can be investigated by the analysis of physiological features such as breathing rhythms, heart rate,…

This work presents a novel approach for characterizing the mechanical behavior of atrial tissue using constitutive neural networks. Based on experimental biaxial tensile test data of healthy human atria, we automatically discover the most…

Heart failure occurs when the heart is not able to pump blood and oxygen to support other organs in the body as it should. Treatments include medications and sometimes hospitalization. Patients with heart failure can have both…

Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…

The left ventricular assist device (LVAD) has been used for end-stage heart failure patients as a therapeutic option. The aortic valve plays a critical role in heart failure and its treatment with LVAD. The cardiovascular-LVAD model is…

Cardiac diseases are one of the leading mortality factors in modern, industrialized societies, which cause high expenses in public health systems. Due to high costs, developing analytical methods to improve cardiac diagnostics is essential.…

Many types of ventricular and atrial cardiac arrhythmias have been discovered in clinical practice in the past 100 years, and these arrhythmias are a major contributor to sudden cardiac death. Ventricular tachycardia, ventricular…

The amount of fat on the surroundings of the heart is correlated to several health risk factors such as carotid stiffness, coronary artery calcification, atrial fibrillation, atherosclerosis, cancer incidence and others. Furthermore, the…

In recent years, human in silico trials have gained significant traction as a powerful approach to evaluate the effects of drugs, clinical interventions, and medical devices. In silico trials not only minimise patient risks but also reduce…

Uncertainty quantification is not yet widely adapted in the design process of engineering components despite its importance for achieving sustainable and resource-efficient structures. This is mainly due to two reasons: 1) Tracing the…

We consider the problem of automatically prescribing oblique planes (short axis, 4 chamber and 2 chamber views) in Cardiac Magnetic Resonance Imaging (MRI). A concern with technologist-driven acquisitions of these planes is the quality and…

Cardiocirculatory mathematical models serve as valuable tools for investigating physiological and pathological conditions of the circulatory system. To investigate the clinical condition of an individual, cardiocirculatory models need to be…

This work investigates the existing capabilities and limitations in numerical modeling of fracture problems in functionally graded materials (FGMs) by means of the well-known finite element code ABAQUS. Quasi-static crack initiation and…

Heart diseases rank among the leading causes of global mortality, demonstrating a crucial need for early diagnosis and intervention. Most traditional electrocardiogram (ECG) based automated diagnosis methods are trained at population level,…

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…