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Left ventricular diastolic dysfunction (LVDD) is a group of diseases that adversely affect the passive phase of the cardiac cycle and can lead to heart failure. While left ventricular end-diastolic pressure (LVEDP) is a valuable prognostic…

Tissues and Organs · Quantitative Biology 2025-01-23 Emilio A. Mendiola , Raza Rana Mehdi , Dipan J. Shah , Reza Avazmohammadi

Accurate reconstruction of cardiac anatomy from sparse clinical images remains a major challenge in patient-specific modeling. While neural implicit functions have previously been applied to this task, their application to mapping…

Coronary arteries and their branches supply blood to myocardium. The obstruction of coronary arteries results in significant loss of myocardium, called acute myocardial infarction, and the number one cause of death globally. Hence,…

Computational Geometry · Computer Science 2017-08-31 Jehyun Chaa , Joonghyun Ryub , Jin-Ho Choi , Deok-Soo Kim

The leading cause of mortality and morbidity worldwide is cardiovascular disease (CVD), with coronary artery disease (CAD) being the largest sub-category. Unfortunately, myocardial infarction or stroke can manifest as the first symptom of…

Signal Processing · Electrical Eng. & Systems 2024-09-10 Matthew Fynn , Kayapanda Mandana , Javed Rashid , Sven Nordholm , Yue Rong , Goutam Saha

Cardiac action potential models allow examination of a variety of cardiac dynamics, including how behavior may change under specific interventions. To study a specific scenario, including patient-specific cases, model parameter sets must be…

Computational Engineering, Finance, and Science · Computer Science 2025-04-21 Darby I. Cairns , Maxfield R. Comstock , Flavio H. Fenton , Elizabeth M. Cherry

Hypoplastic left heart syndrome (HLHS) is a congenital heart disease responsible for 23% of infant cardiac deaths each year. HLHS patients are born with an underdeveloped left heart, requiring several surgeries to reconstruct the aorta and…

Quantitative Methods · Quantitative Biology 2024-09-25 Alyssa M. Taylor-LaPole , L. Mihaela Paun , Dan Lior , Justin D Weigand , Charles Puelz , Mette S. Olufsen

This paper proposes a prototype of a new biofeedback training based on mathematical models of cardiovascular control. For this purpose we develop a low-cost device that is able to record and process arterial pulse wave via…

Neurons and Cognition · Quantitative Biology 2019-02-18 Michel Kana

Automated cardiac segmentation from magnetic resonance imaging datasets is an essential step in the timely diagnosis and management of cardiac pathologies. We propose to tackle the problem of automated left and right ventricle segmentation…

Computer Vision and Pattern Recognition · Computer Science 2017-04-28 Phi Vu Tran

Cardiovascular diseases are widespread among patients with chronic noncommunicable diseases and are one of the leading causes of death, including in the working age. The article presents the relevance of the development and application of…

Machine Learning · Computer Science 2023-08-22 T. V. Afanasieva , A. P. Kuzlyakin , A. V. Komolov

The choice of lung protective ventilation settings for mechanical ventilation has a considerable impact on patient outcome, yet identifying optimal ventilatory settings for individual patients remains highly challenging due to the inherent…

Accurate segmentation of the left ventricle in echocardiography can enable fully automatic extraction of clinical measurements such as volumes and ejection fraction. While models configured by nnU-Net perform well, they are large and slow,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Anders Kjelsrud , Lasse Løvstakken , Erik Smistad , Håvard Dalen , Gilles Van De Vyver

This study performs parameter inference in a partial differential equations system of pulmonary circulation. We use a fluid dynamics network model that takes selected parameter values and mimics the behaviour of the pulmonary haemodynamics…

Cardiovascular modeling has rapidly advanced over the past few decades due to the rising needs for health tracking and early detection of cardiovascular diseases. While 1-D arterial models offer an attractive compromise between…

Left ventricular segmentation is essential for measuring left ventricular function indices. Segmentation of one or several images requires an initial guess of the contour. It is hypothesized here that creating an initial guess by first…

Computer Vision and Pattern Recognition · Computer Science 2015-10-13 Yael Petrank , Nahum Smirin , Yossi Tsadok , Zvi Friedman , Peter Lysiansky , Dan Adam

The echocardiographic measurement of left ventricular ejection fraction (LVEF) is fundamental to the diagnosis and classification of patients with heart failure (HF). In order to quantify LVEF automatically and accurately, this paper…

Deep learning-based cardiac segmentation has seen significant advancements over the years. Many studies have tackled the challenge of anatomically incorrect segmentation predictions by introducing auxiliary modules. These modules either…

Computer Vision and Pattern Recognition · Computer Science 2025-02-24 Zahid Ullah , Jihie Kim

We propose a novel approach to generate samples from the conditional distribution of patient-specific cardiovascular models given a clinically aquired image volume. A convolutional neural network architecture with dropout layers is first…

Quantitative Methods · Quantitative Biology 2021-09-01 Gabriel Maher , Casey Fleeter , Daniele Schiavazzi , Alison Marsden

Decreased myocardial capillary density has been reported as an important histopathological feature associated with various heart disorders. Quantitative assessment of cardiac capillarization typically involves double immunostaining of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Zhao Zhang , Xiwen Chen , William Richardson , Bruce Z. Gao , Abolfazl Razi , Tong Ye

The 19-dimensional TP06 cardiac muscle cell model is reduced to a 17-dimensional version, which satisfies the required conditions for performing an analysis of its dynamics by means of bifurcation theory. The reformulated model is shown to…

Dynamical Systems · Mathematics 2021-05-17 André H. Erhardt , Susanne Solem

Cardiovascular disease (CVD) risk prediction models are essential for identifying high-risk individuals and guiding preventive actions. However, existing models struggle with the challenges of real-world clinical practice as they…

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