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Fluorescence imaging is indispensable to biology and neuroscience. The need for large-scale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional microscopes /…

Optics · Physics 2020-10-29 Yujia Xue , Ian G. Davison , David A. Boas , Lei Tian

Lensless imaging enables exceptionally compact fluorescence sensors, advancing applications in \textit{in vivo} imaging and low-cost, point-of-care diagnostics. These sensors require a filter to block the excitation light while passing…

Image and Video Processing · Electrical Eng. & Systems 2026-02-20 Lukas Harris , Micah Roschelle , Jack Bartley , Mekhail Anwar

Confocal laser endomicroscopy (CLE) is a novel imaging modality that provides in vivo histological cross-sections of examined tissue. Recently, attempts have been made to develop miniaturized in vivo imaging devices, specifically confocal…

Computer Vision and Pattern Recognition · Computer Science 2018-06-22 Saeed Izadi , Kathleen P. Moriarty , Ghassan Hamarneh

We introduce a system capable of focusing light through a multimode fiber in 37ms, one order of magnitude faster than demonstrated in previous reports. As a result, the focus spot can be maintained during significant bending of the fiber,…

In recent years, a great deal of emphasis has been placed on achieving the diffraction limit with large aperture telescopes. For a well matched focal-plane instrument, the diffraction limit provides the highest possible angular resolution…

Astrophysics · Physics 2009-11-11 J. Bland-Hawthorn , A. Horton

Self-supervised monocular depth estimation is a significant task for low-cost and efficient 3D scene perception and measurement in endoscopy. However, the variety of illumination conditions and scene features is still the primary challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Liangjing Shao , Chenkang Du , Benshuang Chen , Xueli Liu , Xinrong Chen

Light field microscopy (LFM) uses a microlens array (MLA) near the sensor plane of a microscope to achieve single-shot 3D imaging of a sample without any moving parts. Unfortunately, the 3D capability of LFM comes with a significant loss of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Fanglin Linda Liu , Grace Kuo , Nick Antipa , Kyrollos Yanny , Laura Waller

Mask-based lensless imaging uses an optical encoder (e.g. a phase or amplitude mask) to capture measurements, then a computational decoding algorithm to reconstruct images. In this work, we evaluate and design lensless encoders based on the…

Most visual odometry algorithm for a monocular camera focuses on points, either by feature matching, or direct alignment of pixel intensity, while ignoring a common but important geometry entity: edges. In this paper, we propose an odometry…

Computer Vision and Pattern Recognition · Computer Science 2017-03-21 Shichao Yang , Sebastian Scherer

Polarization-based vision has gained increasing attention for providing richer physical cues beyond RGB images. While achieving single-shot capture is highly desirable for practical applications, existing Division-of-Focal-Plane (DoFP)…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Shuangfan Zhou , Chu Zhou , Heng Guo , Youwei Lyu , Boxin Shi , Zhanyu Ma , Imari Sato

Recent years have witnessed the tremendous development of fusing fiber-optic imaging with supervised deep learning to enable high-quality imaging of hard-to-reach areas. Nevertheless, the supervised deep learning method imposes strict…

Imaging depth and spectrum have been extensively studied in isolation from each other for decades. Recently, hyperspectral-depth (HS-D) imaging emerges to capture both information simultaneously by combining two different imaging systems;…

Image and Video Processing · Electrical Eng. & Systems 2021-08-17 Seung-Hwan Baek , Hayato Ikoma , Daniel S. Jeon , Yuqi Li , Wolfgang Heidrich , Gordon Wetzstein , Min H. Kim

Depth estimation is a cornerstone of 3D reconstruction and plays a vital role in minimally invasive endoscopic surgeries. However, most current depth estimation networks rely on traditional convolutional neural networks, which are limited…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Bojian Li , Bo Liu , Xinning Yao , Jinghua Yue , Fugen Zhou

Depth estimation from monocular endoscopic images presents significant challenges due to the complexity of endoscopic surgery, such as irregular shapes of human soft tissues, as well as variations in lighting conditions. Existing methods…

Image and Video Processing · Electrical Eng. & Systems 2025-02-07 Dawei Lu , Deqiang Xiao , Danni Ai , Jingfan Fan , Tianyu Fu , Yucong Lin , Hong Song , Xujiong Ye , Lei Zhang , Jian Yang

In turbid media, scattering of light scrambles information of the incident beam and represents an obstacle to optical imaging. Noninvasive imaging through opaque layers is challenging for dynamic and wide-field objects due to unreliable…

Optics · Physics 2018-10-17 Yuan Yuan , Hui Chen

Multispectral imaging plays an important role in many applications from astronomical imaging, earth observation to biomedical imaging. However, the current technologies are complex with multiple alignment-sensitive components, predetermined…

Optics · Physics 2021-09-17 Sujit Kumar Sahoo , Dongliang Tang , Cuong Dang

In astronomy or biological imaging, refractive index inhomogeneities of e.g. atmosphere or tissues induce optical aberrations which degrade the desired information hidden behind the medium. A standard approach consists in measuring these…

Optics · Physics 2023-06-01 Tengfei Wu , Marc Guillon , Gilles Tessier , Pascal Berto

Light-field imaging is an emerging paradigm in biomedical optics, offering the unique ability to capture volumetric information in a single snapshot by encoding both the spatial and angular components of light. Unlike conventional…

Optics · Physics 2025-09-30 Ruixuan Zhao , Xuanwen Hua , Woongjae Baek , Zhaoqiang Wang , Shu Jia , Liang Gao

We aim to track the endoscope location inside the surgical scene and provide 3D reconstruction, in real-time, from the sole input of the image sequence captured by the monocular endoscope. This information offers new possibilities for…

Computer Vision and Pattern Recognition · Computer Science 2016-08-30 Nader Mahmoud , Iñigo Cirauqui , Alexandre Hostettler , Christophe Doignon , Luc Soler , Jacques Marescaux , J. M. M. Montiel

Driven by many applications in a wide span of scientific fields, a myriad of advanced ultrafastimaging techniques have emerged in the last decade, featuring record-high imaging speeds abovea trillion-frame-per-second with long sequence…