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This work is concerned with optical imaging in strongly diffusive environments. We consider a typical setting in optical coherence tomography where a sample is probed by a collection of wavefields produced by a laser and propagating through…

Optics · Physics 2024-12-10 Randy Bartels , Olivier Pinaud , Maxine Varughese

Lensless cameras replace bulky optics with thin modulation masks, enabling compact imaging systems. However, existing methods rely on an idealized model that assumes a globally shift-invariant point spread function (PSF) and sufficiently…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Yu Ren , Xiaoling Zhang , Xu Zhan , Xiangdong Ma , Yunqi Wang , Edmund Y. Lam , Tianjiao Zeng

When light propagates through a multimode optical fibre (MMF), the spatial information it carries is scrambled. Wavefront shaping can undo this scrambling, typically one spatial mode at a time - enabling deployment of MMFs as ultra-thin…

Conventional lens-based imaging techniques have long been limited to capturing only the intensity distribution of objects, resulting in the loss of other crucial dimensions such as spectral data. Here, we report a spectral lens that…

In this study, we address the key challenges concerning the accuracy and effectiveness of depth estimation for endoscopic imaging, with a particular emphasis on real-time inference and the impact of light reflections. We propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Yangke Li

The lensless pinhole camera is perhaps the earliest and simplest form of an imaging system using only a pinhole-sized aperture in place of a lens. They can capture an infinite depth-of-field and offer greater freedom from optical distortion…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Joshua D. Rego , Huaijin Chen , Shuai Li , Jinwei Gu , Suren Jayasuriya

We propose a robust image enhancement algorithm dedicated for muscle fiber specimen images captured by optical microscopes. Blur or out of focus problems are prevalent in muscle images during the image acquisition stage. Traditional image…

Computer Vision and Pattern Recognition · Computer Science 2016-12-20 Xiangfei Kong , Lin Yang

Optical spectroscopy is a fundamental tool in numerous areas of science and technology. Much effort has focused on miniaturizing spectrometers, but thus far at the cost of high spectral resolution and broad operating range. Here, we…

Image transmission through multimode optical fibers has been an area of immense interests driven by the demand for miniature endoscopes in biomedicine and higher speed and capacity in telecommunications. Conventionally, a complex-valued…

Optics · Physics 2020-07-15 Tianrui Zhao , Sebastien Ourselin , Tom Vercauteren , Wenfeng Xia

By replacing the lens with a thin optical element, lensless imaging enables new applications and solutions beyond those supported by traditional camera design and post-processing, e.g. compact and lightweight form factors and visual…

Computer Vision and Pattern Recognition · Computer Science 2022-06-06 Eric Bezzam , Martin Vetterli , Matthieu Simeoni

High-resolution real-time intraocular imaging of retina at the cellular level is very challenging due to the vulnerable and confined space within the eyeball as well as the limited availability of appropriate modalities. A probe-based…

Reconstructing deformable surgical scenes from endoscopic videos is challenging and clinically important. Recent state-of-the-art methods based on implicit neural representations or 3D Gaussian splatting have made notable progress. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Jiwei Shan , Zeyu Cai , Cheng-Tai Hsieh , Yirui Li , Hao Liu , Lijun Han , Hesheng Wang , Shing Shin Cheng

Extended depth of focus (EDOF) optics can enable lower complexity optical imaging systems when compared to active focusing solutions. With existing EDOF optics, however, it is difficult to achieve high resolution and high collection…

Endoscopy is a crucial tool for diagnosing the gastrointestinal tract, but its effectiveness is often limited by a narrow field of view and the dynamic nature of the internal environment, especially in the esophagus, where complex and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Muyang Li , Juming Xiong , Ruining Deng , Tianyuan Yao , Regina N Tyree , Girish Hiremath , Yuankai Huo

In some applications, the object space of light field imaging system is restrictive, such as industrial and medical endoscopes. If the traditional light field imaging system is used in the restrictive object space (ROS) directly but without…

Optics · Physics 2023-12-05 Ping Zhou , Nuo Chen , Yuda Xu , Chengcai Xu

Birefringence, an inherent characteristic of optically anisotropic materials, is widely utilized in various imaging applications ranging from material characterizations to clinical diagnosis. Polarized light microscopy enables…

High-throughput biological imaging is often constrained by a trade-off between acquisition speed and image quality. Fast imaging modalities, such as wide-field fluorescence microscopy, enable large-scale data acquisition but suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Dominik Panek , Carina Rząca , Maksymilian Szczypior , Joanna Sorysz , Krzysztof Misztal , Zbigniew Baster , Zenon Rajfur

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

Biological Physics · Physics 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

Optical endomicroscopy (OEM) is an emerging technology platform with preclinical and clinical imaging applications. Pulmonary OEM via fibre bundles has the potential to provide in vivo, in situ molecular signatures of disease such as…

Computer Vision and Pattern Recognition · Computer Science 2018-08-29 Ahmed Karam Eldaly , Yoann Altmann , Antonios Perperidis , Nikola Krstajic , Tushar Choudhary , Kevin Dhaliwal , Stephen McLaughlin

Recently introduced speckle-correlations based techniques enable noninvasive imaging of objects hidden behind scattering layers. In these techniques the hidden object Fourier amplitude is retrieved from the scattered light autocorrelation,…

Optics · Physics 2022-01-19 Tengfei Wu , Ori Katz , Xiaopeng Shao , Sylvain Gigan