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Long baseline interferometry is now a mature technique in the optical domain. Current interferometers are however highly limited in number of sub apertures and concepts are being developed for future generations of very large optical arrays…
Confocal Raman microscopy, a highly specific and label-free technique for the microscale study of thick samples, often presents difficulties due to weak Raman signals. Inhomogeneous samples introduce wavefront aberrations that further…
Optical imaging systems are generally limited by the depth of field because of the nature of the optics. Therefore, extending depth of field (EDoF) is a fundamental task for meeting the requirements of emerging visual applications. To solve…
Visual SLAM shows significant progress in recent years due to high attention from vision community but still, challenges remain for low-textured environments. Feature based visual SLAMs do not produce reliable camera and structure estimates…
Phase and polarisation of coherent light are highly perturbed by interaction with microstructural changes in pre-malignant tissue, holding promise for label-free early cancer detection in endoscopically accessible tissues such as the…
Multimode optical fibres are hair-thin strands of glass that efficiently transport light. They promise next-generation medical endoscopes that provide unprecedented sub-cellular image resolution deep inside the body. However, confining…
Ultrathin multimode fibers (MMFs) promise endoscopes with hair-scale diameters for accessing sub-millimeter anatomy, but in MMF far-field imaging the required small collection aperture drives speckle-dominated measurements that rapidly…
Significance: Endoscopic screening for esophageal cancer may enable early cancer diagnosis and treatment. While optical microendoscopic technology has shown promise in improving specificity, the limited field of view (<1 mm) significantly…
Conventional microwave imaging schemes, enabled by the ubiquity of coherent sources and detectors, have traditionally relied on frequency bandwidth to retrieve range information, while using mechanical or electronic beamsteering to obtain…
Fibered confocal fluorescence microscopy (FCFM) is a new technique that can be used during a bronchoscopy to analyze the nature of the human bronchial and alveolar mucosa fluorescence microstructure. An endoscopic fibered confocal…
Single-pixel imaging can collect images at the wavelengths outside the reach of conventional focal plane array detectors. However, the limited image quality and lengthy computational times for iterative reconstruction still impede the…
Video endoscopy represents a major advance in the investigation of gastrointestinal diseases. Reviewing endoscopy videos often involves frequent adjustments and reorientations to piece together a complete view, which can be both…
Optical imaging systems are inherently imperfect due to diffraction limits, lens manufacturing tolerances, assembly misalignment, and other physical constraints. In addition, unavoidable camera shake and object motion further introduce…
Flexible needle insertion procedures are common for minimally-invasive surgeries for diagnosing and treating prostate cancer. Bevel-tip needles provide physicians the capability to steer the needle during long insertions to avoid vital…
Fluorescent observation of cells generally suffers from the limited axial resolution due to the elongated point spread function of the microscope optics. Consequently, three-dimensional imaging results in axial resolution being several…
Confocal imaging and phase imaging are powerful tools in life science research and industrial inspection. To coherently link the two techniques with different depth resolutions, we introduce an optical frequency comb (OFC) to microscopy.…
We are now moving into an era where multi-object wide-field surveys, which traditionally use single fibres to observe many targets simultaneously, can exploit compact integral field units in place of single fibres. Current multi-object…
Here, we present a concept based on the realization that a complex medium can be used as a simple interferometer. Changes in the wavefront of an incident coherent beam can be retrieved by analyzing changes in speckle patterns when the beam…
Fiber-form optics extends the high-resolution tomographic imaging capabilities of Optical Coherence Tomography (OCT) to the inside of the human body, i.e., endoscopic OCT. However, it still faces challenges due to the trade-off between…
Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…