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As transistor dimensions continue to shrink, binary devices are rapidly approaching their fundamental limits in power density. In response, multi-valued systems have attracted significant attention due to their enhanced information density.…

Molecular Networks · Quantitative Biology 2026-04-28 Enqiang Zhu , Peize Qiu , Xianhang Luo , Chanjuan Liu , Jin Xu

Harnessing the intrinsic dynamics of physical systems for information processing opens new avenues for computation embodied in matter. Using simulations of a model system, we show that assemblies of DNA tiles capable of self-organizing into…

Soft Condensed Matter · Physics 2025-10-23 Tim E. Veenstra , René van Roij , Marjolein Dijkstra

A theoretical model which takes into account the structural distortion of double-crossover DNA tiles has been studied to investigate its effect on lattice formation sizes. It has been found that a single vector appropriately describes the…

Mesoscale and Nanoscale Physics · Physics 2011-05-12 Seungjae Kim , Junghoon Kim , Pengfei Qian , Jihoon Shin , Rashid Amin , Sang Jung Ahn , Thomas H. LaBean , Moon Ki Kim , Sung Ha Park

This article introduces a novel binary representation of the canonical genetic code based on both the structural similarities of the nucleotides, as well as the physicochemical properties of the encoded amino acids. Each of the four mRNA…

Biological Physics · Physics 2017-03-27 Louis R. Nemzer

Three coarse-grained models of the double-stranded DNA are proposed and compared in the context of mechanical manipulation such as twisting and various schemes of stretching. The models differ in the number of effective beads (between two…

Biomolecules · Quantitative Biology 2015-05-13 Szymon Niewieczerzał , Marek Cieplak

In this paper, we study binary and ternary matrices that are used for CDMA applications that are injective on binary or ternary user vectors. In other words, in the absence of additive noise, the interference of overloaded CDMA can be…

Information Theory · Computer Science 2009-01-15 Sh. Dashmiz , P. Pad , F. Marvasti

The effect of secondary structure on DNA duplex formation is poorly understood. We use a coarse-grained model of DNA to show that specific 3- and 4-base pair hairpins reduce hybridization rates by factors of 2 and 10 respectively, in good…

Soft Condensed Matter · Physics 2015-12-15 John S. Schreck , Thomas E. Ouldridge , Flavio Romano , Petr Sulc , Liam Shaw , Ard A. Louis , Jonathan P. K. Doye

DNA Self-Assembly has emerged as an interdisciplinary field with many intriguing applications such DNA bio-sensor, DNA circuits, DNA storage, drug delivery etc. Tile assembly model of DNA has been studied for various computational…

Emerging Technologies · Computer Science 2015-02-20 Shalin Shah , Parth Dave , Manish K Gupta

We introduce a model of thermalized conformations in space of RNA -or single stranded DNA- molecules, which includes the possibility of hairpin formation. This model contains the usual secondary structure information, but extends it to the…

Soft Condensed Matter · Physics 2007-05-23 Andrea Montanari , Marc Mezard

Rotary motors play key roles in energy transduction, from macroscale windmills to nanoscale turbines such as ATP synthase in cells. Despite our capabilities to construct engines at many scales, developing functional synthetic turbines at…

DNA origami is a widely used method to construct nanostructures by self-assembling designed DNA strands. These structures are often used as "pegboards" for templated assembly of proteins, gold nanoparticles, aptamers, and other molecules,…

Soft Condensed Matter · Physics 2024-11-05 Matthew Sample , Hao Liu , Thong Diep , Michael Matthies , Petr Šulc

This short note introduces a geometric representation for binary (or ternary) sequences. The proposed representation is linked to multivariate data plotting according to the radar chart. As an illustrative example, the binary Hamming…

Information Theory · Computer Science 2021-03-09 H. M. de Oliveira , R. J. Cintra

Most binary superlattices created using DNA functionalization or other approaches rely on particle size differences to achieve compositional order and structural diversity. Here we study two-dimensional (2D) assembly of DNA-functionalized…

Soft Condensed Matter · Physics 2017-03-13 Minseok Song , Yajun Ding , Hasan Zerze , Mark A. Snyder , Jeetain Mittal

Mathematically, ternary coding is more efficient than binary coding. It is little used in computation because technology for binary processing is already established and the implementation of ternary coding is more complicated, but remains…

Artificial Intelligence · Computer Science 2018-07-18 Subhash Kak

A hypercomplex representation of DNA is proposed to facilitate comparison of DNA sequences with fuzzy composition. Using hypercomplex number representation, conventional sequence analysis method, such as, dot matrix analysis, dynamic…

Quantitative Methods · Quantitative Biology 2023-08-03 Jian-Jun Shu , Yajing Li

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

Other Quantitative Biology · Quantitative Biology 2014-03-12 Jian-Jun Shu , Li Shan Ouw

Tile displacement is a newly-recognized mechanism in DNA nanotechnology that exploits principles analogous to toehold-mediated strand displacement but within the context of self-assembled DNA origami tile arrays. Here, we formulate an…

Emerging Technologies · Computer Science 2023-01-06 Erik Winfree , Lulu Qian

Double-stranded DNA `overstretches' at a pulling force of about 65 pN, increasing in length by a factor of 1.7. The nature of the overstretched state is unknown, despite its considerable importance for DNA's biological function and…

Statistical Mechanics · Physics 2009-11-13 Stephen Whitelam , Sander Pronk , Phillip L. Geissler

DNA data storage offers a high-density, long-term alternative to traditional storage systems, addressing the exponential growth of digital data. Composite DNA extends this paradigm by leveraging mixtures of nucleotides to increase storage…

Information Theory · Computer Science 2026-02-13 Busra Tegin , Tolga M Duman

Branched molecules of deoxyribonucleic acid (DNA) can self-assemble into nanostructures through complementary cohesive strand base pairing. The production of DNA nanostructures is valuable in targeted drug delivery and biomolecular…

Combinatorics · Mathematics 2022-03-15 D. Chloe Griffin , Jessica Sorrells
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