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After more than a century of concerted effort, physics still lacks basic principles of spontaneous self-organization. To appreciate why, we first state the problem, outline historical approaches, and survey the present state of the physics…

Statistical Mechanics · Physics 2023-11-27 Adam T. Rupe , James P. Crutchfield

In this essay the ontological structure of reality is explored. The question of reducibility of biology to physics is considered in the context of their ultimate principles. It is shown that biology is an ontologically autonomous science…

General Physics · Physics 2007-05-23 A. Grandpierre

Modeling and simulation are recognized as important aspects of the scientific method for more than 70 years but its adoption in biology has been slow. Debates on its representativeness, usefulness, and whether the effort spent on such…

Quantitative Methods · Quantitative Biology 2023-02-21 Maurice HT Ling

Living systems are thermodynamically open but closed in their organization. In other words, even though their material components turn over constantly, a material-independent property persists, which we call organization. Moreover,…

Quantitative Methods · Quantitative Biology 2025-03-07 Pedro Márquez-Zacarías , Andrés Ortiz-Muñoz , Emma P. Bingham

Instructive influence of environment on heredity has been a debated topic for centuries. Darwin's identification of natural selection coupled to chance variation as the driving force for evolution, against a formal interpretation proposed…

Genomics · Quantitative Biology 2007-05-23 Antoine Danchin

The molecular biology revolution of the last seventy five years has transformed our view of living systems. Scientific explanations of biological phenomena are now synonymous with the identification of the genes, proteins, and signaling…

Biological Physics · Physics 2024-10-29 Pankaj Mehta

In higher organisms, all cells share the same genome, but every cell expresses only a limited and specific set of genes that defines the cell type. During cell division, not only the genome, but also the cell type is inherited by the…

Life has a special status, it even has its own science: biology. In many ways, the logic of life seems to differ from that of atoms, molecules, planets, or any other `inanimate object'. However, life is increasingly measured using…

Other Quantitative Biology · Quantitative Biology 2021-12-16 Marc-Antoine Fardin

Theoretical physics is the search for simple and universal mathematical descriptions of the natural world. In contrast, much of modern biology is an exploration of the complexity and diversity of life. For many, this contrast is prima facie…

Biological Physics · Physics 2024-01-23 William Bialek

The growth, form, and division of prebiotic vesicles, membraneous bags of fluid of varying components and shapes is hypothesized to have served as the substrate for the origin of life. The dynamics of these out-of-equilibrium structures is…

Soft Condensed Matter · Physics 2019-07-24 Teresa Ruiz-Herrero , Thomas G. Fai , L. Mahadevan

Self-organization is the autonomous assembly of a network of interacting components into a stable, organized pattern. This article shows that the process of self-assembly can be encoded in terms of evolutionary entropy, a statistical…

Statistical Mechanics · Physics 2023-05-29 Lloyd A. Demetrius

The University of Maryland (UMD) Biology Education and Physics Education Research Groups are investigating students' views on the role of physics in introductory biology courses. This paper presents data from an introductory course that…

Physics Education · Physics 2015-05-19 Jessica Watkins , Kristi Hall , Edward Redish , Todd Cooke

A natural process is defined as an act, by which a system organizes itself with time. Any natural process drives a system to a state of greater organization. Organization is a progressive change, while evolution is expressed in the effects…

Adaptation and Self-Organizing Systems · Physics 2012-01-09 Atanu Bikash Chatterjee

The dynamic instability of the living systems and the "superposition" of different forms of randomness are viewed as a component of the contingently increasing organization of life along evolution. We briefly survey how classical and…

Other Quantitative Biology · Quantitative Biology 2011-04-07 Marcello Buiatti , Giuseppe Longo

It is not currently possible to create a living organism ab initio due to the overwhelming complexity of biological systems. In fact, the origin of life mechanism, this being how biological organisms form from non-living matter, is unknown.…

Earth and Planetary Astrophysics · Physics 2021-04-09 Darius Modirrousta-Galian , Giovanni Maddalena

Living organisms have some common structures, chemical reactions and molecular structures. The organisms consist of cells with cell division, they have homochirality of protein and carbohydrate units, and metabolism, and genetics, and they…

Populations and Evolution · Quantitative Biology 2025-05-27 Søren Toxvaerd

Biosystems contain an almost infinite amount of vital important details, which together ensure their life. There are, however, some common structures and reactions in the systems: the homochirality of carbohydrates and proteins, the…

Biomolecules · Quantitative Biology 2018-03-06 Soren Toxvaerd

The path toward the emergence of life in our biosphere involved several key events allowing for the persistence, reproduction and evolution of molecular systems. All these processes took place in a given environmental context and required…

Disordered Systems and Neural Networks · Physics 2025-04-14 Ricard Solé , Manlio De Domenico

The sustenance of life depends on the high degree of organization that prevails through different levels of living organisms, from subcellular structures such as biomolecular complexes and organelles to tissues and organs. The physical…

Soft Condensed Matter · Physics 2019-01-14 Hanieh Falahati , Amir Haji-Akbari

The theory of evolution by natural selection cannot be used to evaluate the truth value of the following proposition: Through evolution, there exists at least one species that can adapt to any one given environment. To address this issue,…

Biological Physics · Physics 2022-08-17 Kai Xu