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Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…

Computed Tomography is a powerful imaging technique that allows non-destructive visualization of the interior of physical objects in different scientific areas. In traditional reconstruction techniques the object of interest is mostly…

Image and Video Processing · Electrical Eng. & Systems 2019-05-03 Koen Ruymbeek , Wim Vanroose

Accurate 3D representations of cardiac structures allow quantitative analysis of anatomy and function. In this work, we propose a method for reconstructing complete 3D cardiac shapes from segmentations of sparse planes in CT angiography…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Gino E. Jansen , Carolina Brás , R. Nils Planken , Mark J. Schuuring , Berto J. Bouma , Ivana Išgum

Mathematical modeling at the level of the full cardiovascular system requires the numerical approximation of solutions to a one-dimensional nonlinear hyperbolic system describing flow in a single vessel. This model is often simulated by…

Computational Physics · Physics 2015-04-22 Sebastian Acosta , Charles Puelz , Beatrice Riviere , Daniel J. Penny , Craig G. Rusin

A short sample sequence of a finite-length pulse signal allows for its reconstruction only if the signal has a sparse representation in some basis. The recurrence of the pulse allows for a statistical approach to its reconstruction. We…

Signal Processing · Electrical Eng. & Systems 2023-08-15 Marek W. Rupniewski

We propose a novel algorithm to recover fetal electrocardiogram (ECG) for both the fetal heart rate analysis and morphological analysis of its waveform from two or three trans-abdominal maternal ECG channels. We design an algorithm based on…

Signal Processing · Electrical Eng. & Systems 2019-08-09 Pei-Chun Su , Stephen Miller , Salim Idriss , Piers Barker , Hau-Tieng Wu

Modeling cardiovascular anatomies poses a significant challenge due to their complex, irregular structures and inherent pathological conditions. Numerical simulations, while accurate, are often computationally expensive, limiting their…

Machine Learning · Computer Science 2025-03-25 Navaneeth N , Souvik Chakraborty

Time-resolved CT is an advanced measurement technique that has been widely used to observe dynamic objects, including periodically varying structures such as hearts, lungs, or hearing structures. To reconstruct these objects from CT…

Medical Physics · Physics 2025-06-05 Qianwei Qu , Christian M. Schlepütz , Marco Stampanoni

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Non-invasive measurement of the arterial blood speed gives rise to important healthinformation such as cardio output and blood supplies to vital organs. The magnitude andchange in arterial blood speed are key indicators of the health…

Medical Physics · Physics 2021-10-22 Alex Ce Zhang , Yu-Hwa Lo

4D Flow is an MRI sequence which allows acquisition of 3D images of the heart. The data is typically acquired volumetrically, so it must be reformatted to generate cardiac long axis and short axis views for diagnostic interpretation. These…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Matthieu Le , Jesse Lieman-Sifry , Felix Lau , Sean Sall , Albert Hsiao , Daniel Golden

Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

Quantitative Methods · Quantitative Biology 2024-02-16 Justen R Geddes , Amanda Randles

Mechanical function of the heart during open-chest cardiac surgery is exclusively monitored by echocardiographic techniques. However, little is known about local kinematics, particularly for the reperfused regions after ischemic events. We…

An improved understanding of how vortices develop and propagate under pulsatile flow can shed important light on the mixing and transport processes including the transition to turbulent regime occurring in such systems. For example, the…

Fluid Dynamics · Physics 2019-12-13 Nicasio Barrere , Javier Brum , Alexandre L'Her , Gustavo L. Sarasúa , Cecilia Cabeza

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

Medical Physics · Physics 2020-07-01 Janne M. J. Huttunen , Leo Kärkkäinen , Harri Lindholm

Numerous are the questionings raised by medicine interventionnelle, concerning the hold in charge of the pathologies of the arterial partition (aneurysm, dissection, coarctation, atherosclerosis).for it we made the modeling and the numeric…

Fluid Dynamics · Physics 2009-06-29 H . Alla , M. S. Gueblaoui , M. H. Bensaid

Cardiovascular hemodynamic fields provide valuable medical decision markers for coronary artery disease. Computational fluid dynamics (CFD) is the gold standard for accurate, non-invasive evaluation of these quantities in silico. In this…

Quantitative Methods · Quantitative Biology 2025-08-27 Julian Suk , Guido Nannini , Patryk Rygiel , Christoph Brune , Gianluca Pontone , Alberto Redaelli , Jelmer M. Wolterink

With an aim to investigate the effect of externally imposed body acceleration and magnetic field on pulsatile flow of blood through an arterial segment having stenosis is under consideration in this paper. The flow of blood is presented by…

Numerical Analysis · Mathematics 2012-09-25 G. C. Shit , M. Roy

In the context of numerical simulations of the vascular system, local geometric uncertainties have not yet been examined in sufficient detail due to model complexity and the associated large numerical effort. Such uncertainties are related…

Accurate and efficient modeling of cardiac blood flow is crucial for advancing data-driven tools in cardiovascular research and clinical applications. Recently, the accuracy and availability of computational fluid dynamics (CFD)…

Fluid Dynamics · Physics 2025-07-30 Eneko Lazpita , Jesus Garicano-Mena , Soledad Le Clainche
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