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Optical coherence tomography angiography (OCTA) can visualize vasculature structures, but provides limited information about the blood flow speeds. Here, we present a second generation variable interscan time analysis (VISTA) OCTA, which…

The T-wave of an electrocardiogram (ECG) represents the ventricular repolarization that is critical in restoration of the heart muscle to a pre-contractile state prior to the next beat. Alterations in the T-wave reflect various cardiac…

Applications · Statistics 2010-09-30 Yingchun Zhou , Nell Sedransk

We consider the problem of locating a point-source heart arrhythmia using data from a standard diagnostic procedure, where a reference catheter is placed in the heart, and arrival times from a second diagnostic catheter are recorded as the…

Tissues and Organs · Quantitative Biology 2018-07-10 Chris Vogl , Peng Zheng , Stephen P. Seslar , Aleksandr Y. Aravkin

An arteriovenous fistula, created by artificially connecting segments of a patient's vasculature, is the preferred way to gain access to the bloodstream for kidney dialysis. The increasing power and availability of supercomputing…

Medical Physics · Physics 2021-06-14 J. W. S. McCullough , P. V. Coveney

As experts continue to debate the optimal surgery practice for coronary disease - percutaneous coronary intervention (PCI) or coronary aortic bypass graft (CABG) - computational tools may provide a quantitative assessment of each option.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-09 Boyi Yang , Marina Piccinelli , Gaetano Esposito , Tianli Han , Yasir Bouchi , Bill Gogas , Don Giddens , Habib Samady , Alessandro Veneziani

Fast and realistic coupling of blood flow and vessel wall is of great importance to virtual surgery. In this paper, we propose a novel data-driven coupling method that formulates physics-based blood flow simulation as a regression problem,…

Graphics · Computer Science 2019-01-25 Xuejie Mai , Zhiyong Yuan , Qianqian Tong , Tianchen Yuan , Jianhui Zhao

Electrocardiograms (ECG) analysis is one of the most important ways to diagnose heart disease. This paper proposes an efficient ECG classification method based on Wasserstein scalar curvature to comprehend the connection between heart…

Computational Engineering, Finance, and Science · Computer Science 2022-10-26 Fupeng Sun , Yin Ni , Yihao Luo , Huafei Sun

We report on wide-field imaging of pulsatile microvascular blood flow in the exposed cerebral cortex of a mouse by holographic interferometry. We recorded interferograms of laser light backscattered by the tissue, beating against an…

Medical Physics · Physics 2015-10-08 L. Puyo , I. Ferezou , A. Rancillac , M. Simonutti , M. Paques , J. A. Sahel , M. Fink , M. Atlan

We present an undirected version of the recently introduced flow-augmentation technique: Given an undirected multigraph $G$ with distinguished vertices $s,t \in V(G)$ and an integer $k$, one can in randomized $k^{O(1)} \cdot (|V(G)| +…

Data Structures and Algorithms · Computer Science 2023-02-16 Eun Jung Kim , Stefan Kratsch , Marcin Pilipczuk , Magnus Wahlström

We focus on reducing the computational costs associated with the hydrodynamic stability of solutions of the incompressible Navier-Stokes equations for a Newtonian and viscous fluid in contraction-expansion channels. In particular, we are…

Numerical Analysis · Mathematics 2017-09-01 Giuseppe Pitton , Annalisa Quaini , Gianluigi Rozza

Quantitative angiography (QA) in two dimensions has been instrumental in assessing neurovascular contrast flow patterns, aiding disease severity and treatment outcome evaluations. However, QA requires high spatio-temporal resolution,…

The flow convergence method includes calculation of the proximal isovelocity surface area (PISA) and is widely used to classify mitral regurgitation (MR) with echocardiography. It constitutes a primary decision factor for determination of…

Reconstructing cardiac electrical activity from body surface electric potential measurements results in the severely ill-posed inverse problem in electrocardiography. Many different regularization approaches have been proposed to improve…

Numerical Analysis · Mathematics 2025-11-04 Manuel Haas , Thomas Grandits , Thomas Pinetz , Thomas Beiert , Simone Pezzuto , Alexander Effland

Low-frequency oscillations in the human circulatory system is important for basic physiology and practical applications in clinical medicine. Our objective was to study which mechanism (central or local) is responsible for changes in blood…

Tissues and Organs · Quantitative Biology 2024-11-25 Irina A. Mizeva , Natalia P. Podolyan , Oleg V. Mamontov , Anastasiia V. Sakovskaia , Alexei A. Kamshilin

This study presents a novel quantitative estimation method for total retinal arterial blood flow utilizing real-time Doppler holography at an unprecedented frame rate of 33,000 frames per second. This technique, leveraging high-speed…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Yann Fischer , Zacharie Auray , Olivier Martinache , Marius Dubosc , Noé Topéza , Chloé Magnier , Maxime Boy-Arnould , Michael Atlan

The oscillations of the human heart rate are inherently complex and non-linear -- they are best described by mathematical chaos, and they present a challenge when applied to the practical domain of cardiovascular health monitoring in…

Machine Learning · Computer Science 2025-11-03 Berken Utku Demirel , Christian Holz

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink

In this paper we develop theoretical analysis and numerical reconstruction techniques for the solution of an inverse boundary value problem dealing with the nonlinear, time-dependent monodomain equation, which models the evolution of the…

Analysis of PDEs · Mathematics 2017-01-27 Elena Beretta , Cecilia Cavaterra , Maria Cristina Cerutti , Andrea Manzoni , Luca Ratti

We introduce an ultrahigh-resolution (50\mu m\) robotic micro-CT design for localized imaging of carotid plaques using robotic arms, cutting-edge detector, and machine learning technologies. To combat geometric error-induced artifacts in…

Medical Physics · Physics 2024-06-27 Mengzhou Li , Guibin Zan , Wenbin Yun , Josef Uher , John Wen , Ge Wang

Patients that undergo the arterial switch operation (ASO) to repair transposition of great arteries (TGA) can develop abnormal pulmonary trunk morphology with significant long-term complications. In this study, cardiovascular magnetic…

Medical Physics · Physics 2018-09-18 Francesco Capuano , Yue-Hin Loke , Ileen Cronin , Laura J. Olivieri , Elias Balaras