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Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…
The direct numerical simulation (DNS) of the Taylor--Couette flow in the fully turbulent regime is described. The numerical method extends the work by Quadrio & Luchini (Eur. J. Mech. B / Fluids, v.21, pp.413--427, 2002), and is based on a…
The automatic analysis of ultrasound sequences can substantially improve the efficiency of clinical diagnosis. In this work we present our attempt to automate the challenging task of measuring the vascular diameter of the fetal abdominal…
This paper proposes a data-driven model for solving the inverse problem of electrocardiography, the mathematical problem that forms the basis of electrocardiographic imaging (ECGI). We present a conditional diffusion framework that learns a…
Medical therapy for patients with severe heart disease often relies on left ventricular assist devices (LVADs). It is an ongoing topic of research how complications like stagnation and thrombosis can be prevented by using artificial…
Computer modeling can provide quantitative insight into cardiac fluid dynamics phenomena that are not evident from standard imaging tools. We propose a new approach to modeling left ventricle fluid dynamics based on an image-driven…
We propose a hemodynamic reduced-order model bridging macroscopic and meso-scopic blood flow circulation scales from arteries to capillaries. In silico tree like vascular geometries, mathematically described by graphs, are synthetically…
Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…
Accurate coronary artery segmentation from coronary computed tomography angiography is essential for quantitative coronary analysis and clinical decision support. Nevertheless, reliable segmentation remains challenging because of small…
We develop a framework for efficient streaming reconstructions of turbulent velocity fluctuations from limited sensor measurements with the goal of enabling real-time applications. The reconstruction process is simplified by computing…
Abnormal patterns of ventricular repolarisation contribute to lethal arrhythmias in various cardiac conditions, including inherited and acquired channelopathies, cardiomyopathies, and ischaemic heart disease. However, methods to detect…
Cardiovascular diseases are a leading cause of death in the world, driving the development of patient-specific and benchmark models for blood flow analysis. This chapter provides a theoretical overview of the main categories of Reduced…
Understanding the physics of blood is challenging due to its nature as a suspension of soft particles and the fact that typical problems involve different scales. This is valid also for numerical investigations. In fact, many computational…
Internal haemorrhage, often leading to cardio-vascular arrest happens to be one of the prime sources of high fatality rates in mammals. We propose a simplistic model of fluid flow to specify the location of the haemorrhagic spots, which, if…
In this paper, we present a mathematical and numerical model for blood solidification and its rupture in stenosed arteries. The interaction between the blood flow and an existing stenosis in the arterial wall is modeled as a three…
In this paper, the relation between electrocardiogram (ECG) and photoplethysmogram (PPG) signals is studied, and the waveform of ECG is inferred via the PPG signals. In order to address this inverse problem, a transform is proposed to map…
4D Flow MRI is the state of the art technique for measuring blood flow, and it provides valuable information for inverse problems in the cardiovascular system. However, 4D Flow MRI has a very long acquisition time, straining healthcare…
Algebraic methods applied to the reconstruction of Sparse-view Computed Tomography (CT) can provide both a high image quality and a decrease in the dose received by patients, although with an increased reconstruction time since their…
One-dimensional blood flow models take the general form of nonlinear hyperbolic systems but differ greatly in their formulation. One class of models considers the physically conserved quantities of mass and momentum, while another class…
Atrial fibrillation is a heart rhythm disorder that affects tens of millions people worldwide. The most effective treatment is catheter ablation. This involves irreversible heating of abnormal cardiac tissue facilitated by electroanatomical…