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Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

Cognitive distortions have been closely linked to mental health disorders, yet their automatic detection remains challenging due to contextual ambiguity, co-occurrence, and semantic overlap. We propose a novel framework that combines Large…

Computation and Language · Computer Science 2026-04-20 Jun Seo Kim , Hyemi Kim , Woo Joo Oh , Hongjin Cho , Hochul Lee , Hye Hyeon Kim

Intent is defined for understanding spoken language in existing works. Both textual features and acoustic features involved in medical speech contain intent, which is important for symptomatic diagnosis. In this paper, we propose a medical…

Artificial Intelligence · Computer Science 2024-05-01 Jianzong Wang , Pengcheng Li , Xulong Zhang , Ning Cheng , Jing Xiao

Memory disorders are a central factor in the decline of functioning and daily activities in elderly individuals. The confirmation of the illness, initiation of medication to slow its progression, and the commencement of occupational therapy…

Sound · Computer Science 2024-02-08 Marko Niemelä , Mikaela von Bonsdorff , Sami Äyrämö , Tommi Kärkkäinen

Lip reading, the process of interpreting silent speech from visual lip movements, has gained rising attention for its wide range of realistic applications. Deep learning approaches greatly improve current lip reading systems. However, lip…

Artificial Intelligence · Computer Science 2024-05-03 Linzhi Wu , Xingyu Zhang , Yakun Zhang , Changyan Zheng , Tiejun Liu , Liang Xie , Ye Yan , Erwei Yin

With their growing capabilities, generative large language models (LLMs) are being increasingly investigated for complex medical tasks. However, their effectiveness in real-world clinical applications remains underexplored. To address this,…

Computation and Language · Computer Science 2026-01-27 Paul Grundmann , Dennis Fast , Jan Frick , Thomas Steffek , Felix Gers , Wolfgang Nejdl , Alexander Löser

Objective: We develop a deep learning framework based on the pre-trained Bidirectional Encoder Representations from Transformers (BERT) model using unstructured clinical notes from electronic health records (EHRs) to predict the risk of…

This work describes our group's submission to the PROCESS Challenge 2024, with the goal of assessing cognitive decline through spontaneous speech, using three guided clinical tasks. This joint effort followed a holistic approach,…

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

In Intensive Care Units (ICU), the abundance of multivariate time series presents an opportunity for machine learning (ML) to enhance patient phenotyping. In contrast to previous research focused on electronic health records (EHR), here we…

Machine Learning · Computer Science 2024-10-04 Hollan Haule , Ian Piper , Patricia Jones , Tsz-Yan Milly Lo , Javier Escudero

Medical artificial intelligence (AI) systems, particularly multimodal vision-language models (VLM), often exhibit intersectional biases where models are systematically less confident in diagnosing marginalised patient subgroups. Such bias…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Yupeng Zhang , Adam G. Dunn , Usman Naseem , Jinman Kim

Automated discourse analysis tools based on Natural Language Processing (NLP) aiming at the diagnosis of language-impairing dementias generally extract several textual metrics of narrative transcripts. However, the absence of sentence…

Computation and Language · Computer Science 2017-08-17 Marcos Vinícius Treviso , Christopher Shulby , Sandra Maria Aluísio

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

Artificial intelligence holds strong potential to support clinical decision making in intensive care units where timely and accurate risk assessment is critical. However, many existing models focus on isolated outcomes or limited data…

Linguistic features have shown promising applications for detecting various cognitive impairments. To improve detection accuracies, increasing the amount of data or the number of linguistic features have been two applicable approaches.…

Computation and Language · Computer Science 2019-03-29 Zining Zhu , Jekaterina Novikova , Frank Rudzicz

The potential of multimodal generative artificial intelligence (mAI) to replicate human grounded language understanding, including the pragmatic, context-rich aspects of communication, remains to be clarified. Humans are known to use…

In this work, we present a novel perspective on cognitive impairment classification from speech by integrating speech foundation models that explicitly recognize speech dialects. Our motivation is based on the observation that individuals…

Sound · Computer Science 2026-01-14 Tiantian Feng , Anfeng Xu , Jinkook Lee , Shrikanth Narayanan

Most of medical developments require the ability to identify samples that are anomalous with respect to a target group or control group, in the sense they could belong to a new, previously unseen class or are not class data. In this case…

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…

Several studies have shown that speech and language features, automatically extracted from clinical interviews or spontaneous discourse, have diagnostic value for mental disorders such as schizophrenia and bipolar disorder. They typically…

Computation and Language · Computer Science 2019-07-30 Rohit Voleti , Stephanie Woolridge , Julie M. Liss , Melissa Milanovic , Christopher R. Bowie , Visar Berisha