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Related papers: Learning Linguistic Biomarkers for Predicting Mild…

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Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fangqi Cheng , Surajit Ray , Xiaochen Yang

To understand multifactorial conditions such as Alzheimers disease (AD) we need brain signatures that predict the impact of multiple pathologies and their interactions. To help uncover the relationships between brain circuits and cognitive…

Quantitative Methods · Quantitative Biology 2018-12-31 Alexandra Badea , Natalie A Delpratt , RJ Anderson , Russell Dibb , Yi Qi , Hongjiang Wei , Chunlei Liu , William C Wetsel , Brian B Avants , Carol Colton

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Addressing heart failure (HF) as a prevalent global health concern poses difficulties in implementing innovative approaches for enhanced patient care. Predicting mortality rates in HF patients, in particular, is difficult yet critical,…

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, structural brain changes, and genetic predispositions. This study leverages machine-learning and statistical techniques to investigate…

Applications · Statistics 2025-10-29 Riddhik Basu , Arkaprava Roy

Most approaches to machine learning from electronic health data can only predict a single endpoint. Here, we present an alternative that uses unsupervised deep learning to simulate detailed patient trajectories. We use data comprising…

Machine Learning · Computer Science 2019-10-10 Charles K. Fisher , Aaron M. Smith , Jonathan R. Walsh , the Coalition Against Major Diseases

Early detection of cognitive decline is crucial for enabling interventions that can slow neurodegenerative disease progression. Traditional diagnostic approaches rely on labor-intensive clinical assessments, which are impractical for…

Computation and Language · Computer Science 2025-09-04 Kristin Qi , Youxiang Zhu , Caroline Summerour , John A. Batsis , Xiaohui Liang

Language is a valuable source of clinical information in Alzheimer's Disease, as it declines concurrently with neurodegeneration. Consequently, speech and language data have been extensively studied in connection with its diagnosis. This…

Artificial Intelligence · Computer Science 2020-10-14 Sofia de la Fuente Garcia , Craig Ritchie , Saturnino Luz

This study examines the effectiveness of traditional machine learning classifiers versus deep learning models for detecting the imagined speech using electroencephalogram data. Specifically, we evaluated conventional machine learning…

Machine Learning · Computer Science 2024-12-18 Byung-Kwan Ko , Jun-Young Kim , Seo-Hyun Lee

This study presents the development and testing of a conversational speech system designed for robots to detect speech biomarkers indicative of cognitive impairments in people living with dementia (PLwD). The system integrates a backend…

Computation and Language · Computer Science 2025-02-18 Rohith Perumandla , Young-Ho Bae , Diego Izaguirre , Esther Hwang , Andrew Murphy , Long-Jing Hsu , Selma Sabanovic , Casey C. Bennett

Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

Machine Learning · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

The development of effective treatments for Cerebral Palsy (CP) can begin with the early identification of affected children while they are still in the early stages of the disorder. Pathological issues in the brain can be better diagnosed…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

Sound · Computer Science 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

Due to the rapid innovation of technology and the desire to find and employ biomarkers for neurodegenerative disease, high-dimensional data classification problems are routinely encountered in neuroimaging studies. To avoid over-fitting and…

Machine Learning · Statistics 2018-06-19 Shan Shi , Farouk Nathoo

Alzheimer's disease progression prediction is critical for patients with early Mild Cognitive Impairment (MCI) to enable timely intervention and improve their quality of life. While existing progression prediction techniques demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zhongying Deng , Shujun Wang , Angelica I Aviles-Rivero , Zoe Kourtzi , Carola-Bibiane Schönlieb

In this paper, we combined linguistic complexity and (dis)fluency features with pretrained language models for the task of Alzheimer's disease detection of the 2021 ADReSSo (Alzheimer's Dementia Recognition through Spontaneous Speech)…

Computation and Language · Computer Science 2021-06-17 Yu Qiao , Xuefeng Yin , Daniel Wiechmann , Elma Kerz

One third of stroke survivors have language difficulties. Emerging evidence suggests that their likelihood of recovery depends mainly on the damage to language centers. Thus previous research for predicting language recovery post-stroke has…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Yusuf H. Roohani , Noor Sajid , Pranava Madhyastha , Cathy J. Price , Thomas M. H. Hope

The skip-gram (SG) model learns word representation by predicting the words surrounding a center word from unstructured text data. However, not all words in the context window contribute to the meaning of the center word. For example, less…

Computation and Language · Computer Science 2021-02-18 Dongjae Kim , Jong-Kook Kim

Clinical prediction is an essential task in the healthcare industry. However, the recent success of transformers, on which large language models are built, has not been extended to this domain. In this research, we explore the use of…

Computation and Language · Computer Science 2023-05-08 Zekai Chen , Mariann Micsinai Balan , Kevin Brown
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