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Self-assembly is one of the prevalent strategies used by living systems to fabricate ensembles of precision nanometer-scale structures and devices. The push for analogous approaches to create synthetic nanomaterials has led to the…

DNA self-assembly is an important tool that has a wide range of applications such as building nanostructures, the transport of target virotherapies, and nano-circuitry. Tools from graph theory can be used to encode the biological process of…

Combinatorics · Mathematics 2023-10-09 Cory Johnson , Andrew Lavengood-Ryan

Self-assembly is a fundamental concept in biology and of significant interest to nanotechnology. Significant progress has been made in characterizing and controlling the properties of the resulting structures, both experimentally and…

Soft Condensed Matter · Physics 2024-03-06 Florian M. Gartner , Erwin Frey

Proteinaceous aggregation occurs through self-assembly-- a process not entirely understood. In a recent article [1], an analytical theory for amyloid fibril growth via secondary rather than primary nucleation was presented. Remarkably, with…

Biological Physics · Physics 2010-06-16 Barry D. Ganapol

Protein aggregation is of great importance in biology, e.g., in amyloid fibrillation. The aggregation processes that occur at the cellular scale must be highly stochastic in nature because of the statistical number fluctuations that arise…

Soft Condensed Matter · Physics 2016-06-29 Nitin S. Tiwari , Paul van der Schoot

The Abelian Sandpile Model, seen as a deterministic lattice automaton, on two-dimensional periodic graphs generates complex regular patterns displaying (fractal) self-similarity. In particular, on a variety of lattices and initial…

Statistical Mechanics · Physics 2015-11-12 Sergio Caracciolo , Guglielmo Paoletti , Andrea Sportiello

Sequence-directed assembly processes - such as protein folding - allow the assembly of a large number of structures with high accuracy from only a small handful of fundamental building blocks. We aim to explore how efficiently sequence…

Biological Physics · Physics 2025-03-14 Jeremy Guntoro , Thomas Ouldridge

In this paper, we search for {\it absolute} limitations of the Tile Assembly Model (TAM), along with techniques to work around such limitations. Specifically, we investigate the self-assembly of fractal shapes in the TAM. We prove that no…

Computational Complexity · Computer Science 2008-04-26 Matthew J. Patitz , Scott M. Summers

Highly periodic structures are often said to convey the beauty of nature. However, most material properties are strongly influenced by the defects they contain. On the mesoscopic scale, molecular self-assembly exemplifies this interplay;…

We investigate the power of the Wang tile self-assembly model at temperature 1, a threshold value that permits attachment between any two tiles that share even a single bond. When restricted to deterministic assembly in the plane, no…

Computational Complexity · Computer Science 2015-03-13 Matthew Cook , Yunhui Fu , Robert T. Schweller

Catalytically active colloids maintain non-equilibrium conditions in which they produce and deplete chemicals and hence effectively act as sources and sinks of molecules. While individual colloids that are symmetrically coated do not…

Soft Condensed Matter · Physics 2015-06-11 Rodrigo Soto , Ramin Golestanian

We show the first asymptotically efficient constructions in the so-called "noncooperative planar tile assembly" model. Algorithmic self-assembly is the study of the local, distributed, asynchronous algorithms ran by molecules to…

Computational Complexity · Computer Science 2021-07-19 Pierre-Etienne Meunier , Damien Regnault

One versatile route to the creation of two-dimensional crystal structures on the nanometer to micrometer scale is the self-assembly of colloidal particles at an interface. Here, we explore the crystal phases that can be expected from the…

Soft Condensed Matter · Physics 2020-05-29 Etienne Fayen , Anuradha Jagannathan , Giuseppe Foffi , Frank Smallenburg

The assembly of molecular networks into structures such as random tilings and glasses has recently been demonstrated for a number of two-dimensional systems. These structures are dynamically-arrested on experimental timescales so the…

Statistical Mechanics · Physics 2010-10-14 Andrew Stannard , Matthew O. Blunt , Peter H. Beton , Juan P. Garrahan

The algorithmic self-assembly of shapes has been considered in several models of self-assembly. For the problem of \emph{shape construction}, we consider an extended version of the Two-Handed Tile Assembly Model (2HAM), which contains…

Computational Geometry · Computer Science 2016-08-18 Austin Luchsinger , Robert Schweller , Tim Wylie

Biomolecular condensates self-assemble when proteins and nucleic acids spontaneously demix to form droplets within the crowded intracellular milieu. This simple mechanism underlies the formation of a wide variety of membraneless…

Statistical Mechanics · Physics 2021-06-30 William M. Jacobs

In this paper we study aggregation kinetics in systems of particles functionalised by complementary linkers. Most of the coarse-grained models currently employed to study large-scale self-assembly of these systems rely on effective…

Soft Condensed Matter · Physics 2018-12-24 S. J. Bachmann , M. Petitzon , B. M. Mognetti

In this paper, we explore relationships between two models of systems which are governed by only the local interactions of large collections of simple components: cellular automata (CA) and the abstract Tile Assembly Model (aTAM). While…

Emerging Technologies · Computer Science 2013-09-09 Jacob Hendricks , Matthew J. Patitz

The Watson-Crick complementary properties of DNA make DNA a useful tool for the self-assembly of various target complexes. Concepts from graph theory can be used to model the self-assembling process in which the vertices of the graph…

Combinatorics · Mathematics 2023-02-28 Gabriel Lopez , Cory Johnson

The ability to design and synthesize ever more complicated colloidal particles opens the possibility of self-assembling a zoo of complex structures, including those with one or more self-limited length scales. An undesirable feature of…

Soft Condensed Matter · Physics 2022-03-02 Thomas E. Videbæk , Huang Fang , Daichi Hayakawa , Botond Tyukodi , Michael F. Hagan , W. Benjamin Rogers