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Here we numerically study a model of excitable media, namely, a network with occasionally quiet nodes and connection weights that vary with activity on a short-time scale. Even in the absence of stimuli, this exhibits unstable dynamics,…

Disordered Systems and Neural Networks · Physics 2015-05-19 S. de Franciscis , J. J. Torres , J. Marro

A four-node network consisting of a negative loop controlling a positive one is studied. It models some of the features of the p53 gene network. Using piecewise linear dynamics with thresholds, the allowed dynamical classes are fully…

Molecular Networks · Quantitative Biology 2007-05-23 Carlos Aguirre , Joao Martins , R. Vilela Mendes

We study in this paper the effect of an unique initial stimulation on random recurrent networks of leaky integrate and fire neurons. Indeed given a stochastic connectivity this so-called spontaneous mode exhibits various non trivial…

Neural and Evolutionary Computing · Computer Science 2007-05-23 H. Soula , G. Beslon , O. Mazet

Apoptotic death pathways are frequently activated by death ligand induction and subsequent activation of the membrane proximal signaling module. Death receptors cluster upon binding to death ligands, leading to formation of a membrane…

Cell Behavior · Quantitative Biology 2015-02-02 Subhadip Raychaudhuri , Somkanya C. Raychaudhuri

The study of balanced networks of excitatory and inhibitory neurons has led to several open questions. On the one hand it is yet unclear whether the asynchronous state observed in the brain is autonomously generated, or if it results from…

Neurons and Cognition · Quantitative Biology 2016-09-22 Rodrigo Echeveste , Claudius Gros

Selective control in a population is the ability to control a member of the population while leaving the other members relatively unaffected. The concept of selective control is developed using cell death or apoptosis in heterogeneous cell…

Quantitative Methods · Quantitative Biology 2014-07-29 Diego Calzolari , Giovanni Paternostro , Patrick L. Harrington , Carlo Piermarocchi , Phillip M. Duxbury

Intermittent transitions, associated with critical dynamics and characterized by power-law distributions, are commonly observed during sleep. These critical behaviors are evident at the microscopic level through neuronal avalanches and at…

Physics and Society · Physics 2025-03-28 Xiyun Zhang , Bojun Wang , Hongjie Bi

We investigate the interplay between pre-stress and mechanical properties in random elastic networks. To do this in a controlled fashion, we introduce an algorithm for creating random freestanding frames that support exactly one state of…

Disordered Systems and Neural Networks · Physics 2019-02-20 Anwesha Bose , Mathijs F. J. Vermeulen , Cornelis Storm , Wouter G. Ellenbroek

We study the role of fluctuations in percolation of sparse complex networks. To this end we consider two random correlated realizations of the initial damage of the nodes and we evaluate the fraction of nodes that are expected to remain in…

Physics and Society · Physics 2017-07-12 Ginestra Bianconi

We consider a continuous-time stochastic model of spiking neurons. In this model, we have a finite or countable number of neurons which are vertices in some graph $G$ where the edges indicate the synaptic connection between them. We focus…

Probability · Mathematics 2020-10-27 Morgan André , Léo Planche

Many organisms have an elastic skeleton that consists of a closed shell of epithelial cells that is filled with fluid, and can actively regulate both elastic forces in the shell and hydrostatic pressure inside it. In this work we introduce…

Soft Condensed Matter · Physics 2023-10-13 Ajoy Maji , Yitzhak Rabin

Reasonably large perturbations may push a power grid from its stable synchronous state into an undesirable state. Identifying vulnerabilities in power grids by studying power grid stability against such perturbations can aid in preventing…

Adaptation and Self-Organizing Systems · Physics 2025-08-26 Calvin Alvares , Soumitro Banerjee

Deterministic and stochastic Boolean network models are build for the dynamics of negative feedback loops of the p53 pathways. It is shown that the main function of the negative feedback in the p53 pathways is to keep p53 at a low steady…

Molecular Networks · Quantitative Biology 2009-04-16 Hao Ge , Min Qian

Living systems often function with regulatory interactions, but the question of how activity, stochasticity and regulations work together for achieving different goals still remains puzzling. We propose a stochastic model of an active…

Soft Condensed Matter · Physics 2026-03-02 Tai Han , Fanlong Meng

Self-sustained order can emerge in complex systems due to internal feedback between coupled subsystems. Here, we present our discovery of a non-monotonic emergence of order amidst chaos in a turbulent thermo-acoustic fluid system.…

Fluid Dynamics · Physics 2025-02-19 Aswin Balaji , Shruti Tandon , Norbert Marwan , Jürgen Kurths , R. I. Sujith

When inhibitory neurons constitute about 40% of neurons they could have an important antinociceptive role, as they would easily regulate the level of activity of other neurons. We consider a simple network of cortical spiking neurons with…

Neurons and Cognition · Quantitative Biology 2014-01-28 Fernando Montani , Emilia B. Deleglise , Osvaldo A. Rosso

We consider two types of fluctuations in the mass-action equilibrium in protein binding networks. The first type is driven by relatively slow changes in total concentrations (copy numbers) of interacting proteins. The second type, to which…

Molecular Networks · Quantitative Biology 2009-11-13 Koon-Kiu Yan , Dylan Walker , Sergei Maslov

Consensus, synchronization, formation control, and power grid balance are all examples of virtuous dynamical states that may arise in networks. Here, we focus on how such states can be destabilized from a fundamental perspective; namely, we…

Adaptation and Self-Organizing Systems · Physics 2026-02-10 Amirhossein Nazerian , Sahand Tangerami , Malbor Asllani , David Phillips , Hernan Makse , Francesco Sorrentino

Nowadays, explosive synchronization is a well documented phenomenon occurring in networks when the node frequency and its degree are correlated. This first-order transition, which may coexists with classical synchronization, has been…

Physics and Society · Physics 2023-05-17 Manuel Miranda , Mattia Frasca , Ernesto Estrada

Fluctuation-response relations encode fundamental constraints on nonequilibrium systems. While time-domain static response is bounded by activity and entropy production, finite-frequency extensions for time-dependent perturbations remain…

Statistical Mechanics · Physics 2026-02-24 Jiming Zheng , Zhiyue Lu
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