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We present experimental and theoretical arguments, at the single neuron level, suggesting that neuronal response fluctuations reflect a process that positions the neuron near a transition point that separates excitable and unexcitable…

Neurons and Cognition · Quantitative Biology 2013-12-25 Asaf Gal , Shimon Marom

The emergence and stability of splay states is studied in fully coupled finite networks of N excitable quadratic integrate-and-fire neurons, connected via synapses modeled as pulses of finite amplitude and duration. For such synapses, by…

Disordered Systems and Neural Networks · Physics 2012-08-23 Mario Dipoppa , Martin Krupa , Alessandro Torcini , Boris S. Gutkin

While most models of randomly connected networks assume nodes with simple dynamics, nodes in realistic highly connected networks, such as neurons in the brain, exhibit intrinsic dynamics over multiple timescales. We analyze how the…

Disordered Systems and Neural Networks · Physics 2019-09-11 Samuel P. Muscinelli , Wulfram Gerstner , Tilo Schwalger

We study the interplay between network topology and complex space-time patterns and introduce a concept to analytically predict complex patterns in networks of Stuart-Landau oscillators with linear symmetric and instantaneous coupling based…

Adaptation and Self-Organizing Systems · Physics 2015-02-19 Winnie Poel , Anna Zakharova , Eckehard Schöll

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

Neurons and Cognition · Quantitative Biology 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

Dynamical networks are powerful tools for modeling a broad range of complex systems, including financial markets, brains, and ecosystems. They encode how the basic elements (nodes) of these systems interact altogether (via links) and evolve…

Physics and Society · Physics 2019-03-13 Edward Laurence , Nicolas Doyon , Louis J Dubé , Patrick Desrosiers

We study the occurrence of frequency synchronised states with tunable emergent frequencies in a network of connected systems. This is achieved by the interplay between time scales of nonlinear dynamical systems connected to form a network,…

Chaotic Dynamics · Physics 2018-09-05 Kajari Gupta , G. Ambika

Biological information processing is often carried out by complex networks of interconnected dynamical units. A basic question about such networks is that of reliability: if the same signal is presented many times with the network in…

Chaotic Dynamics · Physics 2015-06-11 Guillaume Lajoie , Kevin K. Lin , Eric Shea-Brown

For infinitely large sparse networks of spiking neurons mean field theory shows that a balanced state of highly irregular activity arises under various conditions. Here we analytically investigate the microscopic irregular dynamics in…

Disordered Systems and Neural Networks · Physics 2009-11-13 Sven Jahnke , Raoul-Martin Memmesheimer , Marc Timme

Phase transitions and critical behavior are crucial issues both in theoretical and experimental neuroscience. We report analytic and computational results about phase transitions and self-organized criticality (SOC) in networks with general…

Adaptation and Self-Organizing Systems · Physics 2016-10-07 L. Brochini , A. A. Costa , M. Abadi , A. C. Roque , J. Stolfi , O. Kinouchi

Molecular simulations as well as single molecule experiments have been widely analyzed in terms order parameters, the latter representing candidate probes for the relevant degrees of freedom. Notwithstanding this approach is very intuitive,…

Chemical Physics · Physics 2015-06-11 Ganna Berezovska , Diego Prada-Gracia , Stefano Mostarda , Francesco Rao

Biological systems (among others) may respond to a large variety of distinct external stimuli, or signals. These perturbations will generally be presented to the system not singly, but in various combinations, so that a proper understanding…

Quantitative Methods · Quantitative Biology 2011-06-24 Dennis Wylie

The mammalian brain could contain dense and sparse network connectivity structures, including both excitatory and inhibitory neurons, but is without any clearly defined output layer. The neurons have time constants, which mean that the…

Neurons and Cognition · Quantitative Biology 2021-06-04 Udaya B. Rongala , Henrik Jörntell

We show that in a drive-response coupling framework extreme events are suppressed in the response system by the dominance of a single driving signal. We validate this approach across three distinct response network topologies, namely (i) a…

Chaotic Dynamics · Physics 2026-02-03 R. Shashangan , S. Sudharsan , Dibakar Ghosh , M. Senthilvelan

Large-scale force generation is essential for biological functions such as cell motility, embryonic development, and muscle contraction. In these processes, forces generated at the molecular level by motor proteins are transmitted by…

Soft Condensed Matter · Physics 2016-04-05 Pierre Ronceray , Chase Broedersz , Martin Lenz

Apoptosis is a highly regulated cell death mechanism involved in many physiological processes. A key component of extrinsically activated apoptosis is the death receptor Fas, which, on binding to its cognate ligand FasL, oligomerize to form…

Cell Behavior · Quantitative Biology 2014-04-10 Kenneth L. Ho , Heather A. Harrington

We prove that complex networks of interactions have the capacity to regulate and buffer unpredictable fluctuations in production events. We show that non-bursty network-driven activation dynamics can effectively regulate the level of…

Physics and Society · Physics 2014-10-15 Guillermo García-Pérez , Marián Boguñá , M. Ángeles Serrano

It was recently conjectured that 1/f noise is a fundamental characteristic of spectral fluctuations in chaotic quantum systems. This conjecture is based on the behavior of the power spectrum of the excitation energy fluctuations, which is…

Chaotic Dynamics · Physics 2016-08-16 E. Faleiro , J. M. G. Gómez , R. A. Molina , L. Muñoz , A. Relaño , J. Retamosa , .

Transient or partial synchronization can be used to do computations, although a fully synchronized network is frequently related to epileptic seizures. Here, we propose a homeostatic mechanism that is capable of maintaining a neuronal…

Adaptation and Self-Organizing Systems · Physics 2024-05-21 Sue L. Rhâmidda , Mauricio Girardi-Schappo , Osame Kinouchi

It has been proposed that neural noise in the cortex arises from chaotic dynamics in the balanced state: in this model of cortical dynamics, the excitatory and inhibitory inputs to each neuron approximately cancel, and activity is driven by…

Disordered Systems and Neural Networks · Physics 2017-04-28 Nimrod Shaham , Yoram Burak
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