Related papers: Porous medium equation to Hele-Shaw flow with gene…
We consider a macroscopic model for the growth of living tissues incorporating pressure-driven dispersal and pressure-modulated proliferation. Assuming a power-law relation between the mechanical pressure and the cell density, the model can…
We present a robust computational framework for Hele-Shaw tumor growth with necrotic cores, a problem identified as the incompressible limit of the Porous Media Equation. Simulating this system presents a fundamental challenge: while the…
We investigate the general Porous Medium Equations with drift and source terms that model tumor growth. Incompressible limit of such models has been well-studied in the literature, where convergence of the density and pressure variables are…
We consider the relationship between Hele-Shaw evolution with drift, the porous medium equation with superharmonic drift, and a congested crowd motion model originally proposed by [MRS]- [MRSV]. We first use viscosity solutions to show that…
We investigate the large time behavior of an agent based model describing tumor growth. The microscopic model combines short-range repulsion and cell division. As the number of cells increases exponentially in time, the microscopic model is…
We study a diffuse interface model describing the motion of two viscous fluids driven by the surface tension in a Hele-Shaw cell. The full system consists of the Cahn-Hilliard equation coupled with the Darcy's law. We address the physically…
In this paper, we consider an age-structured mechanical model for tumor growth. This model takes into account the life-cycle of tumor cells by including an age variable. The underlying process for tumor growth is the same as classical tumor…
We analyze a system of cross-diffusion equations that models the growth of an avascular-tumor spheroid. The model incorporates two nonlinear diffusion effects, degeneracy type and super diffusion. We prove the global existence of weak…
We consider the evolution of two incompressible, immiscible fluids with different densities in porous media, known as the Muskat problem [21], which in two dimensions is analogous to the Hele-Shaw cell [26]. We establish, for a class of…
We consider a diffuse interface model of tumor growth proposed by A.~Hawkins-Daruud et al. This model consists of the Cahn-Hilliard equation for the tumor cell fraction $\varphi$ nonlinearly coupled with a reaction-diffusion equation for…
We derive the porous medium equation from an interacting particle system which belongs to the family of exclusion processes, with nearest neighbor exchanges. The particles follow a degenerate dynamics, in the sense that the jump rates can…
We study a singular limit of the classical parabolic-elliptic Patlak-Keller-Segel (PKS) model for chemotaxis with non linear diffusion. The main result is the $\Gamma$ convergence of the corresponding energy functional toward the perimeter…
We consider the one-dimensional Cauchy problem for the Navier-Stokes equations with degenerate viscosity coefficient in highly compressible regime. It corresponds to the compressible Navier-Stokes system with large Mach number equal to…
We consider a model of congestion dynamics with chemotaxis: The density of cells follows a chemical signal it generates, while subject to an incompressibility constraint. The incompressibility constraint results in the formation of patches,…
Convection-driven porous media flows are common in industrial processes and in nature. The multiscale and multiphase character of these systems and the inherent non-linear flow dynamics make convection in porous media a complex phenomenon.…
A large population limit of the parabolic-parabolic Patlak-Keller-Segel (PKS) system with degenerate, nonlinear diffusion, e.g., of porous medium-type $-\frac{m}{m-1}\mathrm{div}(\rho \nabla \rho^{m-1})$, is studied. We show,…
We consider very weak solutions of the Cauchy problem for the porous medium equation on Cartan-Hadamard manifolds, that are assumed to satisfy general curvature bounds and to be stochastically complete. We identify a class of initial data…
In this work we study a tissue growth model with applications to tumour growth. The model is based on that of Perthame, Quir\'os, and V\'azquez proposed in 2014 but incorporates the advective effects caused, for instance, by the presence of…
A nonlocal interface equation is derived for two-phase fluid flow, with arbitrary wettability and viscosity contrast c=(mu_1-mu_2)/(mu_1+mu_2), in a model porous medium defined as a Hele-Shaw cell with random gap b_0+delta b. Fluctuations…
In this paper, we characterize a degenerate PDE as the gradient flow in the space of nonnegative measures endowed with an optimal transport-growth metric. The PDE of concern, of Hele-Shaw type, was introduced by Perthame et. al. as a…