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We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…

Analysis of PDEs · Mathematics 2015-07-29 Mimi Dai , Eduard Feireisl , Elisabetta Rocca , Giulio Schimperna , Maria Schonbek

We consider experimentally the instability and mass transport of a porous-medium flow in a Hele-Shaw geometry. In an initially stable configuration, a lighter fluid (water) is located over a heavier fluid (propylene glycol). The fluids mix…

Fluid Dynamics · Physics 2015-05-20 Scott Backhaus , Konstantin Turitsyn , R. E. Ecke

We consider the Cauchy problem of the porous medium type reaction-diffusion equation \begin{equation*} \partial_t\rho=\Delta\rho^m+\rho g(\rho),\quad (x,t)\in \mathbb{R}^n\times \mathbb{R}_+,\quad n\geq2,\quad m>1, \end{equation*} where $g$…

Analysis of PDEs · Mathematics 2024-08-30 Qingyou He

We study the incompressible limit of the porous medium equation with a reaction term that is non-monotone with respect to the pressure variable. More specifically we consider reaction terms that are either bistable or monostable. We show…

Analysis of PDEs · Mathematics 2022-08-22 Inwon Kim , Antoine Mellet

An useful approximation for the displacement of two immiscible fluids in a porous medium is the Hele-Shaw model. We consider several liquids with different constant viscosities, inserted between the displacing fluids. The linear stability…

Fluid Dynamics · Physics 2020-08-31 Gelu Paşa}

This paper investigates the incompressible limit of a system modelling the growth of two cells population. The model describes the dynamics of cell densities, driven by pressure exclusion and cell proliferation. It has been shown that…

Analysis of PDEs · Mathematics 2019-01-08 P. Degond , S. Hecht , N. Vauchelet

This paper studies the derivation of the quadratic porous medium equation and a class of cross-diffusion systems from nonlocal interactions. We prove convergence of solutions of a nonlocal interaction equation, resp. system, to solutions of…

Analysis of PDEs · Mathematics 2022-10-10 Martin Burger , Antonio Esposito

We consider a macroscopic model for the dynamics of living tissues incorporating pressure-driven dispersal and pressure-modulated proliferation. Given a power-law constitutive relation between the pressure and cell density, the model can be…

The link between compressible models of tissue growth and the Hele-Shaw free boundary problem of fluid mechanics has recently attracted a lot of attention. In most of these models, only repulsive forces and advection terms are taken into…

Analysis of PDEs · Mathematics 2023-05-11 Charles Elbar , Benoît Perthame , Andrea Poiatti , Jakub Skrzeczkowski

Our aim is to study the limit of the solution of reaction-diffusion porous medium equation with linear drift $\displaystyle\partial_t u -\Delta u^m +\nabla \cdot (u \: V)=g(t,x,u) $, as $m\to\infty.$ We study the problem in bounded domain…

Analysis of PDEs · Mathematics 2023-05-10 Noureddine Igbida

A Hele-Shaw cell is a device used to study fluid flow between two parallel plates separated by a small gap. The governing equation of flow within a Hele-Shaw cell is Darcy's law, which also describes flow through a porous medium. In this…

Fluid Dynamics · Physics 2023-05-25 Dylan Reynolds , Gustavo M. Monteiro , Sriram Ganeshan

Using a recently derived filament model, the stability of fluid filaments in Hele-Shaw cells, driven by a constant pressure gradient, is studied. It is found that thin circular filaments grow if their initial radius exceeds a dimensionless…

Fluid Dynamics · Physics 2026-04-14 Nitay Ben-Shachar , Michael C. Dallaston , Scott W. McCue

Topology changes in multi-phase fluid flows are difficult to model within a traditional sharp interface theory. Diffuse interface models turn out to be an attractive alternative to model two-phase flows. Based on a…

Fluid Dynamics · Physics 2017-08-02 Luca Dedè , Harald Garcke , Kei Fong Lam

A mean-field-type limit from stochastic moderately interacting many-particle systems with singular Riesz potential is performed, leading to nonlocal porous-medium equations in the whole space. The nonlocality is given by the inverse of a…

Analysis of PDEs · Mathematics 2021-09-20 Li Chen , Alexandra Holzinger , Ansgar Jüngel , Nicola Zamponi

A diffused interface model describing the evolution of two conterminous incompressible fluids in a porous medium is discussed. The system consists of the Cahn-Hilliard equation with Flory-Huggins logarithmic potential, coupled via surface…

Analysis of PDEs · Mathematics 2024-07-24 Nitu Lakhmara , Hari Shankar Mahato

We study a model introduced by Perthame and Vauchelet that describes the growth of a tumor governed by Brinkman's Law, which takes into account friction between the tumor cells. We adopt the viscosity solution approach to establish an…

Analysis of PDEs · Mathematics 2017-04-24 Inwon Kim , Olga Turanova

We present a phase-field model for the dynamics of the interface between two inmiscible fluids with arbitrary viscosity contrast in a rectangular Hele-Shaw cell. With asymptotic matching techniques we check the model to yield the right…

Soft Condensed Matter · Physics 2009-10-31 R. Folch , J. Casademunt , A. Hernandez-Machado , L. Ramirez-Piscina

We investigate two-phase flow in porous media and derive a two-scale model, which incorporates pore-scale phase distribution and surface tension into the effective behavior at the larger Darcy scale. The free-boundary problem at the pore…

Analysis of PDEs · Mathematics 2023-07-03 Mathis Kelm , Carina Bringedal , Bernd Flemisch

This paper proposes a model for the growth two interacting populations of cells that do not mix. The dynamics is driven by pressure and cohesion forces on the one hand and proliferation on the other hand. Following earlier works on the…

Cell Behavior · Quantitative Biology 2018-04-12 Alina Chertock , Pierre Degond , Sophie Hecht , Jean-Paul Vincent

We complete previous results about the incompressible limit of both the $n$-dimensional $(n\geq3)$ compressible Patlak-Keller-Segel (PKS) model and its stationary state. As in previous works, in this limit, we derive the weak form of a…

Analysis of PDEs · Mathematics 2022-11-22 Qingyou He , Hai-Liang Li , Benoît Perthame