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Within a fully microscopic setting, we derive a variational principle for the non-equilibrium steady states of chemical reaction networks, valid for time-scales over which chemical potentials can be taken to be slowly varying: at…

Molecular Networks · Quantitative Biology 2015-06-05 Andrea De Martino , Daniele De Martino , Roberto Mulet , Guido Uguzzoni

Can algebraic geometry enhance the sharpness, robustness, and interpretability of modern neural reasoning models by equipping them with a mathematically grounded inductive bias? To answer this, we introduce Tropical Attention, an attention…

Machine Learning · Computer Science 2025-10-24 Baran Hashemi , Kurt Pasque , Chris Teska , Ruriko Yoshida

Finding a common factor of two multivariate polynomials with approximate coefficients is a problem in symbolic-numeric computing. Taking a tropical view on this problem leads to efficient preprocessing techniques, applying polyhedral…

Algebraic Geometry · Mathematics 2008-09-02 Danko Adrovic , Jan Verschelde

An algorithm is designed which decomposes a tropical univariate rational function into a composition of tropical binomials and trinomials. When a function is monotone, the composition consists just of binomials. Similar algorithms are…

Algebraic Geometry · Mathematics 2019-03-04 Dima Grigoriev

Complex networks, comprised of individual elements that interact with each other through reaction channels, are ubiquitous across many scientific and engineering disciplines. Examples include biochemical, pharmacokinetic, epidemiological,…

Mathematical Physics · Physics 2013-06-14 John Goutsias , Garrett Jenkinson

The nuclear reaction network is usually studied via precise calculation of differential equation sets, and much research interest has been focused on the characteristics of nuclides, such as half-life and size limit. In this paper, however,…

Nuclear Theory · Physics 2016-08-30 Liang Zhu , Yu-Gang Ma , Qu Chen , Ding-Ding Han

The analysis of the structure of chemical reaction networks is crucial for a better understanding of chemical processes. Such networks are well described as hypergraphs. However, due to the available methods, analyses regarding network…

Computational Complexity · Computer Science 2013-09-30 Rolf Fagerberg , Christoph Flamm , Daniel Merkle , Philipp Peters , Peter F. Stadler

We present herein an extension of an algebraic statistical method for inferring biochemical reaction networks from experimental data, proposed recently in [3]. This extension allows us to analyze reaction networks that are not necessarily…

Molecular Networks · Quantitative Biology 2009-02-26 Gheorghe Craciun , Casian Pantea , Grzegorz A. Rempala

The automated inference of physically interpretable (bio)chemical reaction network models from measured experimental data is a challenging problem whose solution has significant commercial and academic ramifications. It is demonstrated,…

Neural and Evolutionary Computing · Computer Science 2014-12-22 Dominic P. Searson , Mark J. Willis , Allen Wright

We show that finding the classical bound of broad families of Bell inequalities can be naturally framed as the contraction of an associated tensor network, but in tropical algebra, where the sum is replaced by the minimum and the product is…

Quantum Physics · Physics 2026-02-13 Mengyao Hu , Jordi Tura

Generalizing supertropical algebras, we present a "layered" structure, "sorted" by a semiring which permits varying ghost layers, and indicate how it is more amenable than the "standard" supertropical construction in factorizations of…

Commutative Algebra · Mathematics 2011-08-16 Zur Izhakian , Manfred Knebusch , Louis Rowen

In the last few years there has been a growing interest towards methods for statistical inference and learning based on computational geometry and, notably, tropical geometry, that is, the study of algebraic varieties over the min-plus…

Logic in Computer Science · Computer Science 2025-11-21 Davide Barbarossa , Paolo Pistone

The Bond Graph approach and the Chemical Reaction Network approach to modelling biomolecular systems developed independently. This paper brings together the two approaches by providing a bond graph interpretation of the chemical reaction…

Molecular Networks · Quantitative Biology 2019-07-04 Peter J. Gawthrop , Edmund J. Crampin

The tropical semiring is an algebraic system with addition ``$\max$'' and multiplication ``$+$''. As well as in conventional algebra, linear programming in the tropical semiring has been developed. In this study, we introduce a new type of…

Optimization and Control · Mathematics 2026-02-03 Yuki Nishida

A numerically effective procedure for determining weakly reversible chemical reaction networks that are linearly conjugate to a known reaction network is proposed in this paper. The method is based on translating the structural and…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Multi-valued logical models can be used to describe biological networks on a high level of abstraction based on the network structure and logical parameters capturing regulatory effects. Interestingly, the dynamics of two distinct models…

Dynamical Systems · Mathematics 2016-01-28 Adam Streck , Therese Lorenz , Heike Siebert

In many areas such as computational biology, finance or social sciences, knowledge of an underlying graph explaining the interactions between agents is of paramount importance but still challenging. Considering that these interactions may…

Signal Processing · Electrical Eng. & Systems 2021-04-29 Mircea Moscu , Ricardo A. Borsoi , Cédric Richard , José-Carlos M. Bermudez

In chemical reaction network theory, ordinary differential equations are used to model the temporal change of chemical species concentration. As the functional form of these ordinary differential equations systems is derived from an…

Molecular Networks · Quantitative Biology 2025-02-27 Anna C. M. Thöni , William E. Robinson , Yoram Bachrach , Wilhelm T. S. Huck , Tal Kachman

We use the Litvinov-Maslov correspondence principle to reduce and hybridize networks of biochemical reactions. We apply this method to a cell cycle oscillator model. The reduced and hybridized model can be used as a hybrid model for the…

Molecular Networks · Quantitative Biology 2011-09-21 Vincent Noel , Dima Grigoriev , Sergei Vakulenko , Ovidiu Radulescu

This paper presents an algebraic framework to study sign-sensitivities for reaction networks modeled by means of systems of ordinary differential equations. Specifically, we study the sign of the derivative of the concentrations of the…

Molecular Networks · Quantitative Biology 2019-09-02 Elisenda Feliu