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Under suitable assumptions, the dynamic behaviour of a chemical reaction network is governed by an autonomous set of polynomial ordinary differential equations over continuous variables representing the concentrations of the reactant…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel

Dynamical system models of complex biochemical reaction networks are usually high-dimensional, nonlinear, and contain many unknown parameters. In some cases the reaction network structure dictates that positive equilibria must be unique for…

Dynamical Systems · Mathematics 2008-09-09 Gheorghe Craciun , J. William Helton , Ruth J. Williams

In this work, we examine the process of Tropical Polynomial Division, a geometric method which seeks to emulate the division of regular polynomials, when applied to those of the max-plus semiring. This is done via the approximation of the…

Machine Learning · Computer Science 2019-12-02 Georgios Smyrnis , Petros Maragos

Tropical mathematics redefines the rules of arithmetic by replacing addition with taking a maximum, and by replacing multiplication with addition. After briefly discussing a tropical version of linear algebra, we study polynomials build…

Algebraic Geometry · Mathematics 2019-08-21 Ralph Morrison

The tropical rank of a semimodule of rational functions on a metric graph mirrors the concept of rank in linear algebra. Defined in terms of the maximal number of tropically independent elements within the semimodule, this quantity has…

Algebraic Geometry · Mathematics 2026-03-09 Omid Amini , Stéphane Gaubert , Lucas Gierczak

Reaction networks are a general formalism for describing collections of classical entities interacting in a random way. While reaction networks are mainly studied by chemists, they are equivalent to Petri nets, which are used for similar…

Mathematical Physics · Physics 2021-11-23 John C. Baez

We give a framework for constructing generically optimal homotopies for parametrized polynomial systems from tropical data. Here, generically optimal means that the number of paths tracked is equal to the generic number of solutions. We…

Algebraic Geometry · Mathematics 2024-12-31 Paul Alexander Helminck , Oskar Henriksson , Yue Ren

Tropical mathematics is used to establish a correspondence between certain microscopic and macroscopic objects in statistical models. Tropical algebra gives a common framework for macrosystems (subsets) and their elementary constituents…

Mathematical Physics · Physics 2021-06-01 Mario Angelelli

The Jacobian matrix of a dynamic system and its principal minors play a prominent role in the study of qualitative dynamics and bifurcation analysis. When interpreting the Jacobian as an adjacency matrix of an interaction graph, its…

Molecular Networks · Quantitative Biology 2012-10-02 Hans-Michael Kaltenbach

The large-scale properties of chemical reaction systems, such as the metabolism, can be studied with graph-based methods. To do this, one needs to reduce the information -- lists of chemical reactions -- available in databases. Even for the…

Molecular Networks · Quantitative Biology 2009-09-25 Petter Holme

Recently, concepts from the emerging field of tropical geometry have been used to identify different scaling regimes in chemical reaction networks where dimension reduction may take place. In this paper, we try to formalize these ideas…

Dynamical Systems · Mathematics 2025-02-25 K. U. Kristiansen , A. H. Sarantaris

Model reduction is a central topic in systems biology and dynamical systems theory, for reducing the complexity of detailed models, finding important parameters, and developing multi-scale models for instance. While perturbation theory is a…

Molecular Networks · Quantitative Biology 2014-01-27 Sylvain Soliman , Francois Fages , Ovidiu Radulescu

A reaction network is a chemical system involving multiple reactions and chemical species. Stochastic models of such networks treat the system as a continuous time Markov chain on the number of molecules of each species with reactions as…

Probability · Mathematics 2007-05-23 Karen Ball , Thomas G. Kurtz , Lea Popovic , Greg Rempala

Any mass action network gives rise to a parameterised family of polynomial equations whose positive solutions are the positive equilibria of the network. Here, we consider alternative systems of equations, whose solutions are in smooth,…

Molecular Networks · Quantitative Biology 2026-05-06 Murad Banaji , Elisenda Feliu

In this paper we derive a compact mathematical formulation describing the dynamics of chemical reaction networks that are complex-balanced and are governed by mass action kinetics. The formulation is based on the graph of (substrate and…

Dynamical Systems · Mathematics 2012-12-12 Shodhan Rao , Arjan van der Schaft , Bayu Jayawardhana

The algebraic foundation of tropical polynomial algebra provides the framework for the geometric construction of the supplement and the reversal of tropical varieties, thereby inducing a duality of reduced tropical varieties; for classes of…

Algebraic Geometry · Mathematics 2008-11-04 Zur Izhakian , Louis Rowen

Here, we demonstrate how machine learning enables the prediction of comonomers reactivity ratios based on the molecular structure of monomers. We combined multi-task learning, multi-inputs, and Graph Attention Network to build a model…

Machine Learning · Computer Science 2023-01-04 Tung Nguyen , Mona Bavarian

The number of positive solutions of a system of two polynomials in two variables defined in the field of real numbers with a total of five distinct monomials cannot exceed 15. All previously known examples have at most 5 positive solutions.…

Algebraic Geometry · Mathematics 2017-03-08 Boulos El Hilany

Many physical systems--from mechanical lattices and electrical circuits to biological tissues and architected metamaterials--can be understood as networks transmitting physical quantities. We present a unified mathematical framework for…

Soft Condensed Matter · Physics 2025-08-07 José M. Ortiz-Tavárez , William Stephenson , Xiaoming Mao

We describe a new approach based on tropical optimization techniques to solve the problem of rating alternatives from pairwise comparison data. The problem is formulated to approximate, in the log-Chebyshev sense, pairwise comparison…

Optimization and Control · Mathematics 2016-12-12 N. Krivulin