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Delineating the associations between images and a vector of covariates is of central interest in medical imaging studies. To tackle this problem of image response regression, we propose a novel nonparametric approach in the framework of…

Machine Learning · Statistics 2022-03-04 Daiwei Zhang , Lexin Li , Chandra Sripada , Jian Kang

Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

Brain morphometry from magnetic resonance imaging (MRI) is a consolidated biomarker for many neurodegenerative diseases. Recent advances in this domain indicate that deep convolutional neural networks can infer morphometric measurements…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Rodrigo Santa Cruz , Léo Lebrat , Pierrick Bourgeat , Vincent Doré , Jason Dowling , Jurgen Fripp , Clinton Fookes , Olivier Salvado

Purpose: Conventional MRI is relying on the assumption of the magnetic field being homogeneous in direction and amplitude. However, with the growing interest in portable, affordable point-of-care MRI systems, these assumptions do not…

Medical Physics · Physics 2026-02-17 Fabian Bschorr , Thomas Hüfken , Tobias Lobmeyer , Volker Rasche

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Normative aging trends of the brain can serve as an important reference in the assessment of neurological structural disorders. Such models are typically developed from longitudinal brain image data -- follow-up data of the same subject…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Alphin J Thottupattu , Jayanthi Sivaswamy , Venkateswaran P. Krishnan

In this paper we describe and validate a longitudinal method for whole-brain segmentation of longitudinal MRI scans. It builds upon an existing whole-brain segmentation method that can handle multi-contrast data and robustly analyze images…

Computer Vision and Pattern Recognition · Computer Science 2023-02-13 Stefano Cerri , Douglas N. Greve , Andrew Hoopes , Henrik Lundell , Hartwig R. Siebner , Mark Mühlau , Koen Van Leemput

Deep learning-based methods have achieved prestigious performance for magnetic resonance imaging (MRI) reconstruction, enabling fast imaging for many clinical applications. Previous methods employ convolutional networks to learn the image…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Yidong Zhao , Yi Zhang , Qian Tao

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Jiashun Chen , Donghuan Lu , Yu Zhang , Dong Wei , Munan Ning , Xinyu Shi , Zhe Xu , Yefeng Zheng

Robust forecasting of the future anatomical changes inflicted by an ongoing disease is an extremely challenging task that is out of grasp even for experienced healthcare professionals. Such a capability, however, is of great importance…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Dmitrii Lachinov , Arunava Chakravarty , Christoph Grechenig , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Mathematical morphology is a theory and technique to collect features like geometric and topological structures in digital images. Given a target image, determining suitable morphological operations and structuring elements is a cumbersome…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Yucong Shen , Xin Zhong , Frank Y. Shih

The deformation of the lateral ventricle (LV) shape is widely studied to identify specific morphometric changes associated with diseases. Since LV enlargement is considered a relative change due to brain atrophy, local longitudinal LV…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Wonjung Park , Suhyun Ahn , Jinah Park

Accurate cardiac motion estimation from cine cardiac magnetic resonance (CMR) images is vital for assessing cardiac function and detecting its abnormalities. Existing methods often struggle to capture heart motion accurately because they…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Reza Akbari Movahed , Abuzar Rezaee , Arezoo Zakeri , Colin Berry , Edmond S. L. Ho , Ali Gooya

We present a neural rendering framework that maps a voxelized scene into a high quality image. Highly-textured objects and scene element interactions are realistically rendered by our method, despite having a rough representation as an…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Konstantinos Rematas , Vittorio Ferrari

In this study we propose a deformation-based framework to jointly model the influence of aging and Alzheimer's disease (AD) on the brain morphological evolution. Our approach combines a spatio-temporal description of both processes into a…

Neurons and Cognition · Quantitative Biology 2019-05-27 Raphaël Sivera , Hervé Delingette , Marco Lorenzi , Xavier Pennec , Nicholas Ayache

Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Jadie Adams , Shireen Elhabian

Functional Magnetic Resonance Imaging (fMRI) maps cerebral activation in response to stimuli but this activation is often difficult to detect, especially in low-signal contexts and single-subject studies. Accurate activation detection can…

Applications · Statistics 2023-10-26 Wei-Chen Chen , Ranjan Maitra

We propose a fluid-based registration framework of medical images based on implicit neural representation. By integrating implicit neural representation and Large Deformable Diffeomorphic Metric Mapping (LDDMM), we employ a Multilayer…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Chulong Zhang , Xiaokun Liang

We propose a method to predict the subject-specific longitudinal progression of brain structures extracted from baseline MRI, and evaluate its performance on Alzheimer's disease data. The disease progression is modeled as a trajectory on a…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Alexandre Bône , Maxime Louis , Alexandre Routier , Jorge Samper , Michael Bacci , Benjamin Charlier , Olivier Colliot , Stanley Durrleman

Understanding individual cortical development is essential for identifying deviations linked to neurodevelopmental disorders. However, current normative modelling frameworks struggle to capture fine-scale anatomical details due to their…

Quantitative Methods · Quantitative Biology 2025-08-14 Nashira Baena , Mariana da Silva , Irina Grigorescu , Aakash Saboo , Saga Masui , Jaques-Donald Tournier , Emma C. Robinson