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Longitudinal MRIs are often used to capture the gradual deterioration of brain structure and function caused by aging or neurological diseases. Analyzing this data via machine learning generally requires a large number of ground-truth…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Edith V Sullivan , Adolf Pfefferbaum , Greg Zaharchuk , Kilian M Pohl

In this work, we propose a modeling procedure for fMRI data analysis using a Bayesian Matrix-Variate Dynamic Linear Model (MVDLM). With this type of model, less complex than the more traditional temporal-spatial models, we are able to take…

Applications · Statistics 2020-01-22 Johnatan Cardona Jiménez , Carlos A. de B. Pereira , Victor Fossaluza

Brain aging is a regional phenomenon, a facet that remains relatively under-explored within the realm of brain age prediction research using machine learning methods. Voxel-level predictions can provide localized brain age estimates that…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Neha Gianchandani , Mahsa Dibaji , Johanna Ospel , Fernando Vega , Mariana Bento , M. Ethan MacDonald , Roberto Souza

We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

We propose a geometric framework for longitudinal multi-parametric MRI analysis based on patient-specific energy modelling in sequence space. Rather than operating on images with spatial networks, each voxel is represented by its…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Kartikay Tehlan , Lukas Förner , Sina Wendrich , Nico Schmutzenhofer , Michael Frühwald , Matthias Wagner , Nassir Navab , Thomas Wendler

Deep learning models have achieved state-of-the-art results in estimating brain age, which is an important brain health biomarker, from magnetic resonance (MR) images. However, most of these models only provide a global age prediction, and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-25 Neha Gianchandani , Mahsa Dibaji , Mariana Bento , Ethan MacDonald , Roberto Souza

Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative…

Longitudinal fMRI datasets hold great promise for the study of neurodegenerative diseases, but realizing their potential depends on extracting accurate fMRI-based brain measures in individuals over time. This is especially true for rare,…

We develop a learning framework for building deformable templates, which play a fundamental role in many image analysis and computational anatomy tasks. Conventional methods for template creation and image alignment to the template have…

Computer Vision and Pattern Recognition · Computer Science 2019-10-14 Adrian V. Dalca , Marianne Rakic , John Guttag , Mert R. Sabuncu

Vessel dynamics simulation is vital in studying the relationship between geometry and vascular disease progression. Reliable dynamics simulation relies on high-quality vascular meshes. Most of the existing mesh generation methods highly…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Dengqiang Jia , Xinnian Yang , Xiaosong Xiong , Shijie Huang , Feiyu Hou , Li Qin , Kaicong Sun , Kannie Wai Yan Chan , Dinggang Shen

MR vascular Fingerprinting proposes to use the MR Fingerprinting framework to quantitatively and simultaneously map several microvascular characteristics at a sub-voxel scale. The initial implementation assessed the local blood oxygenation…

Simulating aging in 3D brain MRI scans can reveal disease progression patterns in neurological disorders such as Alzheimer's disease. Current deep learning-based generative models typically approach this problem by predicting future scans…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Jaivardhan Kapoor , Jakob H. Macke , Christian F. Baumgartner

Vestibular schwannomas (VS) are benign tumors that are generally managed by active surveillance with MRI examination. To further assist clinical decision-making and avoid overtreatment, an accurate prediction of tumor growth based on…

Image and Video Processing · Electrical Eng. & Systems 2024-04-05 Yunjie Chen , Jelmer M. Wolterink , Olaf M. Neve , Stephan R. Romeijn , Berit M. Verbist , Erik F. Hensen , Qian Tao , Marius Staring

This study presents a new computational approach for simulating the microbial decomposition of organic matter, from 3D micro-computed tomography (micro-CT) images of soil. The method employs a valuated graph of connected voxels to simulate…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Mouad Klai , Olivier Monga , Mohamed Soufiane Jouini , Valérie Pot

Deep generative models have shown success in generating 3D shapes with different representations. In this work, we propose Neural Volumetric Mesh Generator(NVMG) which can generate novel and high-quality volumetric meshes. Unlike the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Yan Zheng , Lemeng Wu , Xingchao Liu , Zhen Chen , Qiang Liu , Qixing Huang

Deep learning-based medical image segmentation and surface mesh generation typically involve a sequential pipeline from image to segmentation to meshes, often requiring large training datasets while making limited use of prior geometric…

Large vision-language models (VLMs) have evolved from general-purpose applications to specialized use cases such as in the clinical domain, demonstrating potential for decision support in radiology. One promising application is assisting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Zhifan Jiang , Dong Yang , Vishwesh Nath , Abhijeet Parida , Nishad P. Kulkarni , Ziyue Xu , Daguang Xu , Syed Muhammad Anwar , Holger R. Roth , Marius George Linguraru

Traditional voxel-level multiple testing procedures in neuroimaging, mostly $p$-value based, often ignore the spatial correlations among neighboring voxels and thus suffer from substantial loss of power. We extend the…

Applications · Statistics 2016-07-29 Hai Shu , Bin Nan , Robert Koeppe

Modeling disease progression is crucial for improving the quality and efficacy of clinical diagnosis and prognosis, but it is often hindered by a lack of longitudinal medical image monitoring for individual patients. To address this…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Xu Cao , Kaizhao Liang , Kuei-Da Liao , Tianren Gao , Wenqian Ye , Jintai Chen , Zhiguang Ding , Jianguo Cao , James M. Rehg , Jimeng Sun

Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…

Neurons and Cognition · Quantitative Biology 2025-08-26 Yanwen Wang , Xinglin Zhao , Yijin Song , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen