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A model of pattern formation in living systems is presented. The pattern is achieved by the sequential interaction of two signaling pathways. The coupling of the pattern to the (thick) epithelial sheet changes is given, when the Gauss…

Tissues and Organs · Quantitative Biology 2009-05-11 Frederick W. Cummings

A mass ejection model in a time-dependent random environment with both temporal and spatial correlations is introduced. When the environment has a finite correlation length, individual particle trajectories are found to diffuse at large…

Chaotic Dynamics · Physics 2012-03-28 Giorgio Krstulovic , Rehab Bitane , Jeremie Bec

A remarkable phenomenon in the time evolution of many networks such as cultural, political, national and economic systems, is the recurrent transition between the states of union and division of nodes. In this work, we propose a…

Physics and Society · Physics 2015-06-18 J. Jiang , R. Wang , M. Pezeril , Q. A. Wang

Risk spreading in bacterial populations is generally regarded as a strategy to maximize survival. Here, we study its role during range expansion of a genetically diverse population where growth and motility are two alternative traits. We…

Populations and Evolution · Quantitative Biology 2014-08-26 Matthias Reiter , Steffen Rulands , Erwin Frey

The purpose of this paper is to implement a random death process into a persistent random walk model which produces subballistic superdiffusion (L\'{e}vy walk). We develop a Markovian model of cell motility with the extra residence variable…

Statistical Mechanics · Physics 2015-05-20 Sergei Fedotov , Abby Tan , Andrey Zubarev

A small portion of a tissue defines a microstate in gene expression space. Mutations, epigenetic events or external factors cause microstate displacements which are modeled by combining small independent gene expression variations and large…

Populations and Evolution · Quantitative Biology 2022-05-19 Roberto Herrero , Dario A. Leon , Augusto Gonzalez

Plasmids are major players in Horizontal Gene Transfer mechanisms, hence they are highly variable in their gene content and length. We propose a model for the fitness of a plasmid as a function of its length, which predicts diminishing…

Populations and Evolution · Quantitative Biology 2014-11-04 Alice Ledda , Luca Ferretti

We employed the method of virial expansion in order to compute the retarded density correlation function (generalized diffusion propagator) in the critical random matrix ensemble in the limit of strong multifractality. We found that the…

Disordered Systems and Neural Networks · Physics 2012-09-03 V. E. Kravtsov , O. M. Yevtushenko , P. Snajberk , E. Cuevas

Variations of transport efficiency in structured environments between distinct individuals in actively self-propelled systems is both hard to study and poorly understood. Here, we study the transport of a non-tumbling {\ecoli} strain, an…

Soft Condensed Matter · Physics 2023-08-28 Pooja Chopra , David Quint , Ajay Gopinathan , Bin Liu

Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random…

Biological Physics · Physics 2009-11-07 L. C. Hsieh , L. F. Luo , F. M. Ji , H. C. Lee

We formulate a kinetic model of DNA replication that quantitatively describes recent results on DNA replication in the in vitro system of Xenopus laevis prior to the mid-blastula transition. The model describes well a large amount of…

Biological Physics · Physics 2018-11-06 John Herrick , Suckjoon Jun , John Bechhoefer , Aaron Bensimon

A dynamical theory for the evolution of the genetic code is presented, which accounts for its universality and optimality. The central concept is that a variety of collective, but non-Darwinian, mechanisms likely to be present in early…

Populations and Evolution · Quantitative Biology 2009-11-13 Kalin Vetsigian , Carl Woese , Nigel Goldenfeld

The problem of the directionality of genome evolution is studied from the information-theoretic view. We propose that the function-coding information quantity of a genome always grows in the course of evolution through sequence duplication,…

Genomics · Quantitative Biology 2011-08-05 Liaofu Luo

In this paper we use an individual-based model and its associated kinetic equation to study the generation of long jumps in the motion of E. coli. These models relate the run-and-tumble process to the intracellular reaction where the…

Analysis of PDEs · Mathematics 2019-11-11 Weiran Sun , Min Tang , Xiaoru Xue

The distributions of species lifetimes and species in space are related, since species with good local survival chances have more time to colonize new habitats and species inhabiting large areas have higher chances to survive local…

Populations and Evolution · Quantitative Biology 2019-02-18 Tobias Rogge , David Jones , Barbara Drossel , Korinna T. Allhoff

In this paper, we examine the long-time dynamics of an epidemic model whose diffusion and reaction terms involve nonlocal effects described by suitable convolution operators.The spreading front of the disease is represented by the free…

Analysis of PDEs · Mathematics 2022-03-01 Rong Wang , Yihong Du

Various bacterial strains (e.g. strains belonging to the genera Bacillus, Paenibacillus, Serratia and Salmonella) exhibit colonial branching patterns during growth on poor semi-solid substrates. These patterns reflect the bacterial…

Condensed Matter · Physics 2009-10-31 Yonathan Kozlovsky , Inon Cohen , Ido Golding , Eshel Ben-Jacob

Marine viruses shape the structure of the microbial community. They are, thus, a key determinant of the most important biogeochemical cycles in the planet. Therefore, a correct description of the ecological and evolutionary behavior of…

Populations and Evolution · Quantitative Biology 2013-12-20 Juan A. Bonachela , Simon A. Levin

We introduce a general class of continuous univariate distributions with positive support obtained by transforming the class of two-piece distributions. We show that this class of distributions is very flexible, easy to implement, and…

Applications · Statistics 2015-11-06 Francisco J. Rubio , Yili Hong

Truncated Levy flights are stochastic processes which display a crossover from a heavy-tailed Levy behavior to a faster decaying probability distribution function (pdf). Putting less weight on long flights overcomes the divergence of the…

Condensed Matter · Physics 2009-11-10 I. M. Sokolov , A. V. Chechkin , J. Klafter