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Mechanical strain and stress play a major role in biological processes such as wound healing or morphogenesis. To assess this role quantitatively, fixed or live images of tissues are acquired at a cellular precision in large fields of…

Tissues and Organs · Quantitative Biology 2019-06-12 M. Durande , S. Tlili , T. Homan , B. Guirao , F. Graner , H. Delanoë-Ayari

The morphology of the sperm head has often been correlated with the outcome of in vitro fertilization (IVF), and has been shown to be the sole parameter in semen of value in predicting the success of intracytoplasmic sperm injection (ICSI)…

The spatial structure of single photons is becoming an extensively explored resource used for facilitating the free-space quantum key distribution and quantum computation as well as for benchmarking the limits of quantum entanglement…

Quantum Physics · Physics 2016-11-08 Radosław Chrapkiewicz , Michał Jachura , Konrad Banaszek , Wojciech Wasilewski

In this paper, a review of indirect microwave holography for through-wall imaging is presented. Indirect microwave holography is an imaging technique, enabling the complex object scattered fields (amplitude and phase) to be mathematically…

Applied Physics · Physics 2019-08-27 Okan Yurduseven , Michael Elsdon

Common-path digital in-line holography is considered as a valuable 3D diagnostic techniques for a wide range of applications. This configuration is cost effective and relatively immune to variation in the experimental environment.…

Instrumentation and Detectors · Physics 2016-01-20 Nicolas Verrier , Corinne Fournier , Anthony Cazier , Thierry Fournel

A lensless digital holography enables wide-field microscopic imaging without the limitations imposed by optical lens performance. However, conventional holographic imaging often relies on magnifying optical systems to compensate for the low…

Optics · Physics 2025-06-24 Byung Gyu Chae

Microscopy enables direct observation of cellular morphology in 3D, with transmitted-light methods offering low-cost, minimally invasive imaging and fluorescence microscopy providing specificity and contrast. Virtual staining combines these…

Scanning X-ray nanodiffraction microscopy is a powerful technique for spatially resolving nanoscale structural morphologies by diffraction contrast. One of the critical challenges in experimental nanodiffraction data analysis is posed by…

Applied Physics · Physics 2024-06-26 Aileen Luo , Tao Zhou , Martin V. Holt , Andrej Singer , Mathew J. Cherukara

In this paper, we propose a new method to characterize the temporal structure of arbitrary optical laser pulses with low pulse energies. This approach is based on strong field photoelectron holography with the glory rescattering effect as…

Atomic Physics · Physics 2020-04-29 J. F. Tao , J. Cai , Q. Z. Xia , J. Liu

This paper presents a method for time-lapse 3D cell analysis. Specifically, we consider the problem of accurately localizing and quantitatively analyzing sub-cellular features, and for tracking individual cells from time-lapse 3D confocal…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Jiaxiang Jiang , Amil Khan , S. Shailja , Samuel A. Belteton , Michael Goebel , Daniel B. Szymanski , B. S. Manjunath

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

Tissue oxygenation and perfusion can be an indicator for organ viability during minimally invasive surgery, for example allowing real-time assessment of tissue perfusion and oxygen saturation. Multispectral imaging is an optical modality…

Computer Vision and Pattern Recognition · Computer Science 2017-06-23 Geoffrey Jones , Neil T Clancy , Xiaofei Du , Maria Robu , Simon Arridge , Daniel S Elson , Danail Stoyanov

When a laser-cooled atomic sample is optically excited, the envelope of coherent forward scattering can often be decomposed into a few complex Gaussian profiles. The convenience of Gaussian propagation helps addressing key challenges in…

Atomic Physics · Physics 2024-12-31 Xing Huang , Yuzhuo Wang , Jian Zhao , Saijun Wu

Optical images of transparent three-dimensional objects can be different from a replica of the object's cross section in the image plane due to refraction at the surface or in the body of the object. Simulations of the object's image are…

Recently, an optical meta concept called the Phasor Field (P-Field) was proposed that yields great quality in the reconstruction of hidden objects imaged by non-line-of-sight (NLOS) imaging. It is based on virtual sinusoidal modulation of…

Optics · Physics 2019-04-03 Syed Azer Reza , Marco La Manna , Sebastian Bauer , Andreas Velten

Grating interferometer is a state of art x-ray imaging approach, which can simultaneously acquire information of x-ray attenuation, phase shift, and small angle scattering. This approach is very sensitive to micro-structural variation and…

Medical Physics · Physics 2015-09-21 Wenxiang Cong , Yan Xi , Ge Wang

Despite its potential for label-free particle diagnostics, holographic microscopy is limited by specialized processing methods that struggle to generalize across diverse settings. We introduce a deep learning architecture leveraging human…

Optics · Physics 2024-11-26 Shyam Kumar , Jiarong Hong

Rapid, comprehensive, and accurate cell phenotyping without compromising viability, is crucial to many important biomedical applications, including stem-cell therapy, drug screening, and liquid biopsy. Typical image cytometry methods…

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue, but lacks functional information. We present dynamic full-field optical coherence tomography to image living human induced…

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