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Scintillating homogeneous detectors represent the state of the art in electromagnetic calorimetry. Moreover, the currently neglected crystalline nature of the most common inorganic scintillators can be exploited to achieve an outstanding…

Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For example, fluorescence microscopy provides unique functional…

Anterior Segment Optical Coherence Tomography (AS-OCT) is an emerging imaging technique with great potential for diagnosing anterior uveitis, a vision-threatening ocular inflammatory condition. A hallmark of this condition is the presence…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Boyu Chen , Ameenat L. Solebo , Daqian Shi , Jinge Wu , Paul Taylor

Surfaces formed by extracellular polymeric substances enclosing individual and some small communities of {\it Acidithiobacillus ferrooxidans} on plates of hydrophobic silicon and hydrophilic mica are analyzed by means of atomic force…

Biological Physics · Physics 2007-05-23 Alberto Saa , Omar Teschke

Measuring microorganisms in food products is a critical issue for food safety and human health. Although various approaches for detecting low-levels of microorganisms in food have been developed, they require high-cost, complex equipment,…

Quantitative Methods · Quantitative Biology 2016-03-25 Jonghee Yoon , KyeoReh Lee , YongKeun Park

Over the last decade, single-molecule optical microscopy has become the gold-standard approach to decipher complex molecular processes in cellular environments. [1-3] Single-molecule fluorescence microscopy has several advantages such as…

Biological Physics · Physics 2017-11-15 Edakkattuparambil Sidharth Shibu , Nadezda Varkentina , Laurent Cognet , Brahim Lounis

Scattering scanning near-field optical microscopy enables optical imaging and characterization of plasmonic devices with nanometer-scale resolution well below the diffraction limit. This technique enables developers to probe and understand…

Centrifuges serve as essential instruments in modern experimental sciences, facilitating a wide range of routine sample processing tasks that necessitate material sedimentation. However, the study for real time observation of the dynamical…

Biological Physics · Physics 2023-08-09 Yuanyuan Wei , Dehua Hu , Bijie Bai , Chenqi Meng , Tsz Kin Chan , Xing Zhao , Yuye Wang , Yi-Ping Ho , Wu Yuan , Ho-Pui Ho

Time-domain sampling of arbitrary electric fields with sub-cycle resolution enables a complete time-frequency analysis of a system's response to electromagnetic illumination. This provides access to dynamic information that is not provided…

We report on a ptychographical coherent diffractive imaging experiment in the water window with focused soft X-rays at $500~\mathrm{eV}$. An X-ray beam with high degree of coherence was selected for ptychography at the P04 beamline of the…

Rapid, comprehensive, and accurate cell phenotyping without compromising viability, is crucial to many important biomedical applications, including stem-cell therapy, drug screening, and liquid biopsy. Typical image cytometry methods…

Scanning fluorescence correlation spectroscopy (SFCS) with a scan path perpendicular to the membrane plane was introduced to measure diffusion and interactions of fluorescent components in free standing biomembranes. Using a confocal laser…

Biomolecules · Quantitative Biology 2018-06-04 Paul Müller , Petra Schwille , Thomas Weidemann

We describe here measurements with a new device, the "dichroicon," a Winston-style light concentrator built out of dichroic reflectors, which could allow large-scale neutrino detectors to sort photons by wavelength with small overall light…

Instrumentation and Detectors · Physics 2020-04-22 Tanner Kaptanoglu , Meng Luo , Ben Land , Amanda Bacon , Josh Klein

Fish diseases in aquaculture constitute a significant hazard to nutriment security. Identification of infected fishes in aquaculture remains challenging to find out at the early stage due to the dearth of necessary infrastructure. The…

Computer Vision and Pattern Recognition · Computer Science 2021-05-11 Md Shoaib Ahmed , Tanjim Taharat Aurpa , Md. Abul Kalam Azad

Image simulation remains under-exploited for the most widely used biological phase microscopy methods, because of difficulties in simulating partially coherent illumination. We describe an open-source toolbox, microlith…

Optics · Physics 2014-05-14 Shalin B. Mehta , Rudolf Oldenbourg

We developed a Bessel light sheet fluorescence microscopy (LSFM) system to enable high-speed, wide-field intra-vital imaging of zebrafish and other thick biological samples. This system uses air objectives for the convenient mounting of…

Optics · Physics 2023-11-07 Chuhui Wang , Jiaju Chen , Cuiyi Peng , Zhenglin Chen , Dongmei Yu , Peiwu Qin

Optical imaging plays a critical role in advancing our understanding of three dimensional dynamics of biological systems. Coherent imaging (CI) methods exploit spatial phase information, encoded through propagation of coherent signal light…

Optics · Physics 2015-07-24 Jeffrey J. Field , David G. Winters , Randy A. Bartels

We propose a novel approach to the important fundamental problem of detecting weak optical fields at the few photon level. The ability to detect with high efficiency (>99%), and to distinguish the number of photons in a given time interval…

Quantum Physics · Physics 2009-11-07 Daniel James , Paul Kwiat

Over the last decades, the use of magnetic nanoparticles in research and commercial applications has increased dramatically. However, direct detection of trace quantities remains a challenge in terms of equipment cost, operating conditions…

Characterizing the anchoring properties of smectic liquid crystals (LCs) in contact with bacterial solutions is crucial for developing biosensing platforms. In this study, we investigate the anchoring properties of a smectic LC when exposed…

Soft Condensed Matter · Physics 2023-06-23 Vajra S. Badha , Tagbo H. R. Niepa , Mohamed Amine Gharbi