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This paper focuses on pattern matching in the DNA sequence. It was inspired by a previously reported method that proposes encoding both pattern and sequence using prime numbers. Although fast, the method is limited to rather small pattern…

Computer Vision and Pattern Recognition · Computer Science 2016-11-21 Janja Paliska Soldo , Ana Sovic Krzic , and Damir Sersic

In computational biology and bioinformatics, the manner to understand evolution processes within various related organisms paid a lot of attention these last decades. However, accurate methodologies are still needed to discover genes…

Neural and Evolutionary Computing · Computer Science 2016-11-15 Bassam AlKindy , Christophe Guyeux , Jean-François Couchot , Michel Salomon , Jacques M. Bahi

Fluorescence lifetime imaging (FLI) is a widely used technique in the biomedical field for measuring the decay times of fluorescent molecules, providing insights into metabolic states, protein interactions, and ligand-receptor bindings.…

Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run. This…

Quantitative Methods · Quantitative Biology 2016-11-18 Stephanie Dodson , Darrell O. Ricke , Jeremy Kepner

Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these…

Genome-wide association studies generate very large datasets that require scalable analysis algorithms. In this report we describe the GEDI software package, which implements efficient algorithms for performing several common tasks in the…

Data Structures and Algorithms · Computer Science 2016-09-08 Justin Kennedy , Ion I. Mandoiu , Bogdan Pasaniuc

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

Genetic Algorithms (GAs) are used to solve search and optimization problems in which an optimal solution can be found using an iterative process with probabilistic and non-deterministic transitions. However, depending on the problem's…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-23 Matheus F. Torquato , Marcelo A. C. Fernandes

Lattice Quantum Chromodynamics simulations typically spend most of the runtime in inversions of the Fermion Matrix. This part is therefore frequently optimized for various HPC architectures. Here we compare the performance of the Intel Xeon…

Computational Physics · Physics 2014-11-18 O. Kaczmarek , C. Schmidt , P. Steinbrecher , M. Wagner

This paper describes a scalable active learning pipeline prototype for large-scale brain mapping that leverages high performance computing power. It enables high-throughput evaluation of algorithm results, which, after human review, are…

The efficient execution of image processing algorithms is an active area of Bioinformatics. In image processing, one of the classes of algorithms or computing pattern that works with irregular data structures is the Irregular Wavefront…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-05-04 Jeremias Gomes , George Teodoro

Deep Neural Network (DNN) inference is emerging as the fundamental bedrock for a multitude of utilities and services. CPUs continue to scale up their raw compute capabilities for DNN inference along with mature high performance libraries to…

The runtime of a Lattice QCD simulation is dominated by a small kernel, which calculates the product of a vector by a sparse matrix known as the "Dslash" operator. Therefore, this kernel is frequently optimized for various HPC…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-09-05 O. Kaczmarek , C. Schmidt , P. Steinbrecher , Swagato Mukherjee , M. Wagner

Genomic sequence alignment is an important research topic in bioinformatics and continues to attract significant efforts. As genomic data grow exponentially, however, most of alignment methods face challenges due to their huge computational…

Computational Engineering, Finance, and Science · Computer Science 2018-06-07 Hanyu Jiang , Narayan Ganesan , Yu-Dong Yao

Similarity search is one of the most fundamental computations that are regularly performed on ever-increasing protein datasets. Scalability is of paramount importance for uncovering novel phenomena that occur at very large scales. We…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-06 Oguz Selvitopi , Saliya Ekanayake , Giulia Guidi , Muaaz G. Awan , Georgios A. Pavlopoulos , Ariful Azad , Nikos Kyrpides , Leonid Oliker , Katherine Yelick , Aydın Buluç

Analysis of processing time and similarity of images generated between CPU and GPU architectures and sequential and parallel programming. For image processing a computer with AMD FX-8350 processor and an Nvidia GTX 960 Maxwell GPU was used,…

Deep learning has become widely used in complex AI applications. Yet, training a deep neural network (DNNs) model requires a considerable amount of calculations, long running time, and much energy. Nowadays, many-core AI accelerators (e.g.,…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-12 Yuxin Wang , Qiang Wang , Shaohuai Shi , Xin He , Zhenheng Tang , Kaiyong Zhao , Xiaowen Chu

The conjugate gradient (CG) algorithm is among the most essential and time consuming parts of lattice calculations with staggered quarks. We test the performance of CG and dslash, the key step in the CG algorithm, on the Intel Xeon Phi,…

High Energy Physics - Lattice · Physics 2014-11-11 Ruizi Li , Steven Gottlieb

Graph Neural Networks (GNNs) are powerful tools for processing graph-structured data, increasingly used for large-scale real-world graphs via sampling-based inference methods. However, inherent characteristics of neighbor sampling lead to…

Hardware Architecture · Computer Science 2025-03-04 Yi Luo , Yaobin Wang , Qi Wang , Yingchen Song , Huan Wu , Qingfeng Wang , Jun Huang

Community detection is the problem of identifying natural divisions in networks. Efficient parallel algorithms for identifying such divisions is critical in a number of applications, where the size of datasets have reached significant…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-24 Subhajit Sahu