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Interferometry provides one of the possible routes to ultra-high angular resolution for X-ray and gamma-ray astronomy. Sub-micro-arc-second angular resolution, necessary to achieve objectives such as imaging the regions around the event…

Instrumentation and Methods for Astrophysics · Physics 2009-07-31 G. K. Skinner , J. F. Krizmanic

X-ray microscopy has been an indispensable tool to image nanoscale properties for materials research. One of its recent advances is to extend microscopic studies to the time domain for visualizing the dynamics of nanoscale phenomena.…

Mesoscale and Nanoscale Physics · Physics 2025-03-25 Haidan Wen , Mathew J. Cherukara , Martin V. Holt

Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…

The authors present a review of the systematic studies of the structure of macroscopically planar thin films at the air-liquid interface (water, alkali solution and silica hydrosol). A common feature of the considered works is the…

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

In this short paper we introduce a variant of the approach to inverting the X-ray transform that originated in the author's work with Uhlmann. The new method is based on semiclassical analysis and eliminates the need for using sufficiently…

Differential Geometry · Mathematics 2020-12-29 András Vasy

A method to calculate particle fluxes applicable in most of the spectroscopy techniques is described. Flux intensities of backscattered or absorbed electrons and emitted photons are calculated using a method of convergence to solve the…

Materials Science · Physics 2015-06-05 C. Figueroa , N. Nieva , H. Brizuela , S. P. Heluani

As light travels through a disordered medium such as biological tissues, it undergoes multiple scattering events. This phenomenon is detrimental to in-depth optical microscopy, as it causes a drastic degradation of contrast, resolution and…

We consider the design and analysis of multi-factor experiments using fractional factorial and incomplete designs within the potential outcome framework. These designs are particularly useful when limited resources make running a full…

Methodology · Statistics 2022-01-31 Nicole E. Pashley , Marie-Abele C. Bind

We propose a general method for optimization with semi-infinite constraints that involve a linear combination of functions, focusing on the case of the exponential function. Each function is lower and upper bounded on sub-intervals by…

Optimization and Control · Mathematics 2014-01-13 Bogdan Dumitrescu , Bogdan C. Sicleru , Florin Avram

We propose an imaging system and methodology for mapping soft-tissue samples in three dimensions, with micron-scale and isotropic spatial resolution, with low-concentrations as well as in the absence of heavy metal staining. We used hard…

Instrumentation and Detectors · Physics 2023-12-21 Michela Esposito , Nicole Schieber , Alessandro Olivo , Yannick Schwab , Marco Endrizzi

Fluorescence microscopy is an important and extensively utilised tool for imaging biological systems. However, the image resolution that can be obtained has a limit as defined through the laws of diffraction. Demand for improved resolution…

Biological Physics · Physics 2007-08-27 James H. Rice

In a previous paper, we reviewed theoretically some of the available processing schemes for X-ray wavefront sensing based on random modulation. We here show experimental applications of the technique for characterising both refractive and…

Instrumentation and Detectors · Physics 2020-02-24 Sebastien Berujon , Ruxandra Cojocaru , Pierre Piault , Rafael Celestre , Thomas Roth , Raymond Barrett , Eric Ziegler

The analysis of secondary quantitative data extracted from high-resolution synchrotron X-ray computed tomography scans represents a significant challenge for users. While a number of methods have been introduced for processing large…

Human-Computer Interaction · Computer Science 2025-05-16 Anja Heim , Thomas Lang , Christoph Heinzl

X-ray ptychography utilizes overlapping illuminations to reconstruct the object's phase and absorption signal with spatial resolutions much smaller than the focus size. Usually, the illumination overlap is chosen to be between 50% and 60%…

Materials Science · Physics 2022-07-29 Felix Wittwer , Peter Modregger

This paper describes the setup of two different solutions for laboratory X-ray microscopy working with geometric magnification. One setup uses thin-film transmission targets with an optimized tungsten-layer thickness and the electron gun…

Instrumentation and Detectors · Physics 2015-06-11 Thomas Ebensperger , Philipp Stahlhut , Frank Nachtrab , Simon Zabler , Randolf Hanke

Despite the tremendous progresses in wavefront control through or inside complex scattering media, several limitations prevent reaching practical feasibility for nonlinear imaging in biological tissues. While the optimization of nonlinear…

Optics · Physics 2016-12-06 Hilton B. de Aguiar , Sylvain Gigan , Sophie Brasselet

Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

Optics · Physics 2021-07-07 Ivan Vishniakou , Johannes D. Seelig

Machine learning methods for computational imaging require uncertainty estimation to be reliable in real settings. While Bayesian models offer a computationally tractable way of recovering uncertainty, they need large data volumes to be…

Machine Learning · Computer Science 2020-08-24 Francesco Tonolini , Jack Radford , Alex Turpin , Daniele Faccio , Roderick Murray-Smith

Imaging through optical multimode fibers (MMFs) has the potential to enable hair-thin endoscopes that reduce the invasiveness of imaging deep inside tissues and organs. Current approaches predominantly require active wavefront shaping and…

Optics · Physics 2021-12-13 Szu-Yu Lee , Vicente J. Parot , Brett E. Bouma , Martin Villiger
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