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Cross-encoder models, which jointly encode and score a query-item pair, are prohibitively expensive for direct k-nearest neighbor (k-NN) search. Consequently, k-NN search typically employs a fast approximate retrieval (e.g. using BM25 or…

Information Retrieval · Computer Science 2023-10-24 Nishant Yadav , Nicholas Monath , Manzil Zaheer , Andrew McCallum

High read depth can be used to assemble short sequence repeats. The existing genome assemblers fail in repetitive regions of longer than average read. I propose a new algorithm for a DNA assembly which uses the relative frequency of reads…

Genomics · Quantitative Biology 2015-01-08 Robert M. Nowak

In this paper we present and evaluate a parallel algorithm for solving a minimum spanning tree (MST) problem for supercomputers with distributed memory. The algorithm relies on the relaxation of the message processing order requirement for…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-10-18 Artem Mazeev , Alexander Semenov , Alexey Simonov

The task of understanding and interpreting the complex information encoded within genomic sequences remains a grand challenge in biological research and clinical applications. In this context, recent advancements in large language model…

Genomics · Quantitative Biology 2024-09-25 Qihang Zhao , Chi Zhang , Weixiong Zhang

Coresets are compact representations of data sets such that models trained on a coreset are provably competitive with models trained on the full data set. As such, they have been successfully used to scale up clustering models to massive…

Machine Learning · Statistics 2018-06-08 Olivier Bachem , Mario Lucic , Andreas Krause

Compressive sensing (CS) is an effective approach for fast Magnetic Resonance Imaging (MRI). It aims at reconstructing MR images from a small number of under-sampled data in k-space, and accelerating the data acquisition in MRI. To improve…

Computer Vision and Pattern Recognition · Computer Science 2017-05-22 Yan Yang , Jian Sun , Huibin Li , Zongben Xu

With the rapid advancements in medical data acquisition and production, increasingly richer representations exist to characterize medical information. However, such large-scale data do not usually meet computing resource constraints or…

Motivation The Burrows-Wheeler transform (BWT) is the foundation of many algorithms for compression and indexing of text data, but the cost of computing the BWT of very large string collections has prevented these techniques from being…

Data Structures and Algorithms · Computer Science 2015-03-20 Anthony J. Cox , Markus J. Bauer , Tobias Jakobi , Giovanna Rosone

Memristive in-memory sorting has been proposed recently to improve hardware sorting efficiency. Using iterative in-memory min computations, data movements between memory and external processing units can be eliminated for improved latency…

Hardware Architecture · Computer Science 2022-02-22 Lianfeng Yu , Zhaokun Jing , Yuchao Yang , Yaoyu Tao

Efficient text indexing data structures have enabled large-scale genomic sequence analysis and are used to help solve problems ranging from assembly to read mapping. However, these data structures typically assume that the underlying…

Genomics · Quantitative Biology 2016-04-13 Nitish Gupta , Komal Sanjeev , Tim Wall , Carl Kingsford , Rob Patro

We present a selective sampling method designed to accelerate the training of deep neural networks. To this end, we introduce a novel measurement, the minimal margin score (MMS), which measures the minimal amount of displacement an input…

Machine Learning · Computer Science 2019-11-19 Berry Weinstein , Shai Fine , Yacov Hel-Or

We consider the problem of subset selection for $\ell_{p}$ subspace approximation, i.e., given $n$ points in $d$ dimensions, we need to pick a small, representative subset of the given points such that its span gives $(1+\epsilon)$…

Computational Geometry · Computer Science 2021-03-23 Amit Deshpande , Rameshwar Pratap

We introduce an improved version of RECKONER, an error corrector for Illumina whole genome sequencing data. By modifying its workflow we reduce the computation time even 10 times. We also propose a new method of determination of $k$-mer…

Genomics · Quantitative Biology 2017-03-03 Maciej Dlugosz , Sebastian Deorowicz , Marek Kokot

Motivation: High-coverage sequencing data have significant, yet hard to exploit, redundancy. Most FASTQ compressors cannot efficiently compress the DNA stream of large datasets, since the redundancy between overlapping reads cannot be…

Data Structures and Algorithms · Computer Science 2014-09-19 Szymon Grabowski , Sebastian Deorowicz , Łukasz Roguski

Unstructured pruning reduces the memory footprint in deep neural networks (DNNs). Recently, researchers proposed different types of structural pruning intending to reduce also the computation complexity. In this work, we first suggest a new…

Artificial Intelligence · Computer Science 2021-10-22 Itay Hubara , Brian Chmiel , Moshe Island , Ron Banner , Seffi Naor , Daniel Soudry

Kernel $k$-means clustering is a powerful tool for unsupervised learning of non-linearly separable data. Since the earliest attempts, researchers have noted that such algorithms often become trapped by local minima arising from…

Machine Learning · Statistics 2020-11-13 Debolina Paul , Saptarshi Chakraborty , Swagatam Das , Jason Xu

The fall of prices of the high-throughput genome sequencing changes the landscape of modern genomics. A number of large scale projects aimed at sequencing many human genomes are in progress. Genome sequencing also becomes an important aid…

Data Structures and Algorithms · Computer Science 2017-03-03 Sebastian Deorowicz , Agnieszka Danek , Marcin Niemiec

In this paper, we first propose a new iterative algorithm, called the K-sets+ algorithm for clustering data points in a semi-metric space, where the distance measure does not necessarily satisfy the triangular inequality. We show that the…

Data Structures and Algorithms · Computer Science 2017-05-12 Cheng-Shang Chang , Chia-Tai Chang , Duan-Shin Lee , Li-Heng Liou

A well-known bottleneck of Min-Sum-of-Square Clustering (MSSC, the celebrated $k$-means problem) is to tackle the presence of outliers. In this paper, we propose a Partial clustering variant termed PMSSC which considers a fixed number of…

Computational Complexity · Computer Science 2023-06-01 Nicolas Dupin , Frank Nielsen

Genome sequencing has become a central focus in computational biology. A genome study typically begins with sequencing, which produces millions to billions of short DNA fragments known as reads. Read mapping aligns these reads to a…