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This study introduces a novel approach, combining substruct counting, $k$-mers, and Daylight-like fingerprints, to expand the representation of chemical structures in SMILES strings. The integrated method generates comprehensive molecular…

Biomolecules · Quantitative Biology 2024-04-01 Sarwan Ali , Prakash Chourasia , Murray Patterson

Motivation: Next generation methods of DNA sequencing produce relatively high rate of reading errors, which interfere with de novo genome assembly of newly sequenced organisms and particularly affect the quality of SNP detection important…

Genomics · Quantitative Biology 2019-07-31 Oleg Fokin , Anastasia Bakulina , Igor Seledtsov , Victor Solovyev

The Matrix Bandwidth Minimization Problem (MBMP) seeks for a simultaneous reordering of the rows and the columns of a square matrix such that the nonzero entries are collected within a band of small width close to the main diagonal. The…

Artificial Intelligence · Computer Science 2020-07-28 Gabriela Czibula , Gloria Cerasela Crisan , Camelia-M. Pintea , Istvan-Gergely Czibula

The utility of DNA sequence substrings (k-mers) in alignment-free phylogenetic classification, including that of bacteria and viruses, is increasingly recognized. However, its biological basis eludes many twenty-first century practitioners.…

Populations and Evolution · Quantitative Biology 2019-04-29 Donald R. Forsdyke

High-resolution magnetic resonance imaging (MRI) is essential in clinical diagnosis. However, its long acquisition time remains a critical issue. Parallel imaging (PI) is a common approach to reduce acquisition time by periodically skipping…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Hao Li , Yusheng Zhou , Jianan Liu , Xiling Liu , Tao Huang , Zhihan Lyu , Weidong Cai , Wei Chen

With the huge influx of various data nowadays, extracting knowledge from them has become an interesting but tedious task among data scientists, particularly when the data come in heterogeneous form and have missing information. Many data…

Machine Learning · Computer Science 2017-05-11 Tsuyoshi Kato , Rachelle Rivero

Genome assembly using high throughput data with short reads, arguably, remains an unresolvable task in repetitive genomes, since when the length of a repeat exceeds the read length, it becomes difficult to unambiguously connect the flanking…

Quantitative Methods · Quantitative Biology 2013-07-31 Viraj Deshpande , Eric DK Fung , Son Pham , Vineet Bafna

The advent of next-generation sequencing (NGS) has revolutionized genomic research by enabling cost-effective, high-throughput sequencing of a diverse range of organisms. This breakthrough has unleashed a "Cambrian explosion" in genomic…

We propose a new compression scheme for genomic data given as sequence fragments called reads. The scheme uses a reference genome at the decoder side only, freeing the encoder from the burdens of storing references and performing…

Information Theory · Computer Science 2023-02-10 Yotam Gershon , Yuval Cassuto

Overlapping clustering problem is an important learning issue in which clusters are not mutually exclusive and each object may belongs simultaneously to several clusters. This paper presents a kernel based method that produces overlapping…

Machine Learning · Computer Science 2012-11-30 Chiheb-Eddine Ben N'Cir , Nadia Essoussi

In this paper authors have presented a power efficient scheme for implementing a spike sorting module. Spike sorting is an important application in the field of neural signal acquisition for implantable biomedical systems whose function is…

Neural and Evolutionary Computing · Computer Science 2018-02-27 Anand Kumar Mukhopadhyay , Indrajit Chakrabarti , Arindam Basu , Mrigank Sharad

Sorting is a primitive operation that is a building block for countless algorithms. As such, it is important to design sorting algorithms that approach peak performance on a range of hardware architectures. Graphics Processing Units (GPUs)…

Data Structures and Algorithms · Computer Science 2017-03-31 Henri Casanova , John Iacono , Ben Karsin , Nodari Sitchinava , Volker Weichert

Minimal perfect hashing is the problem of mapping a static set of $n$ distinct keys into the address space $\{1,\ldots,n\}$ bijectively. It is well-known that $n\log_2(e)$ bits are necessary to specify a minimal perfect hash function (MPHF)…

Data Structures and Algorithms · Computer Science 2023-04-13 Giulio Ermanno Pibiri , Yoshihiro Shibuya , Antoine Limasset

The extraction of k-mers from sequencing reads is an important task in many bioinformatics applications, such as all DNA sequence analysis methods based on de Bruijn graphs. These methods tend to be more accurate when the used k-mers are…

Genomics · Quantitative Biology 2021-10-01 Miika Leinonen , Leena Salmela

The integration of quantum computing into classical machine learning architectures has emerged as a promising approach to enhance model efficiency and computational capacity. In this work, we introduce the Quantum Kernel-Based Long…

Quantum Physics · Physics 2024-11-21 Yu-Chao Hsu , Tai-Yu Li , Kuan-Cheng Chen

Searching for similar genomic sequences is an essential and fundamental step in biomedical research and an overwhelming majority of genomic analyses. State-of-the-art computational methods performing such comparisons fail to cope with the…

Data Structures and Algorithms · Computer Science 2024-07-11 Mohammed Alser , Julien Eudine , Onur Mutlu

This paper develops a memory-efficient approach for Sequential Pattern Mining (SPM), a fundamental topic in knowledge discovery that faces a well-known memory bottleneck for large data sets. Our methodology involves a novel hybrid trie data…

Databases · Computer Science 2024-07-30 Amin Hosseininasab , Willem-Jan van Hoeve , Andre A. Cire

A central limitation of multiple-acquisition magnetic resonance imaging (MRI) is the degradation in scan efficiency as the number of distinct datasets grows. Sparse recovery techniques can alleviate this limitation via randomly undersampled…

Image and Video Processing · Electrical Eng. & Systems 2017-10-03 L Kerem Senel , Toygan Kilic , Alper Gungor , Emre Kopanoglu , H Emre Guven , Emine U Saritas , Aykut Koc , Tolga Cukur

Token compression is essential for reducing the computational and memory requirements of transformer models, enabling their deployment in resource-constrained environments. In this work, we propose an efficient and hardware-compatible token…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Junzhu Mao , Yang Shen , Jinyang Guo , Yazhou Yao , Xiansheng Hua

Metric learning methods for dimensionality reduction in combination with k-Nearest Neighbors (kNN) have been extensively deployed in many classification, data embedding, and information retrieval applications. However, most of these…

Machine Learning · Computer Science 2017-07-07 Martin Renqiang Min , Hongyu Guo , Dongjin Song