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This paper presents an accurate short-read mapper for next-generation sequencing data which is widely used in the 1000 Genomes Project, and human clinical and other species genome studies.

Genomics · Quantitative Biology 2015-06-17 Wan-Ping Lee , Michael Stromberg , Alistair Ward , Chip Stewart , Erik Garrison , Gabor T. Marth

Accelerators for sparse matrix multiplication are important components in emerging systems. In this paper, we study the main challenges of accelerating Sparse Matrix Multiplication (SpMM). For the situations that data is not stored in the…

Hardware Architecture · Computer Science 2019-06-04 Pareesa Ameneh Golnari , Sharad Malik

Cardiovascular magnetic resonance (CMR) imaging is the gold standard for diagnosing several heart diseases due to its non-invasive nature and proper contrast. MR imaging is time-consuming because of signal acquisition and image formation…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Kian Anvari Hamedani , Narges Razizadeh , Shahabedin Nabavi , Mohsen Ebrahimi Moghaddam

Deep neural networks (DNNs) have been proven to be effective in solving many real-life problems, but its high computation cost prohibits those models from being deployed to edge devices. Pruning, as a method to introduce zeros to model…

Machine Learning · Computer Science 2021-12-22 Fei Sun , Minghai Qin , Tianyun Zhang , Xiaolong Ma , Haoran Li , Junwen Luo , Zihao Zhao , Yen-Kuang Chen , Yuan Xie

Deep Neural Networks (DNN) could forget the knowledge about earlier tasks when learning new tasks, and this is known as \textit{catastrophic forgetting}. While recent continual learning methods are capable of alleviating the catastrophic…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Li Yang , Zhezhi He , Junshan Zhang , Deliang Fan

Spiking neural networks (SNNs) provide an energy-efficient solution by utilizing the spike-based and sparse nature of biological systems. Since the advent of Transformers, SNNs have struggled to compete with artificial networks on long…

Neural and Evolutionary Computing · Computer Science 2024-10-24 Yan Zhong , Ruoyu Zhao , Chao Wang , Qinghai Guo , Jianguo Zhang , Zhichao Lu , Luziwei Leng

Magnetic resonance imaging (MRI) is mainly limited by long scanning time and vulnerable to human tissue motion artifacts, in 3D clinical scenarios. Thus, k-space undersampling is used to accelerate the acquisition of MRI while leading to…

Image and Video Processing · Electrical Eng. & Systems 2022-01-11 Shengke Xue , Ruiliang Bai , Xinyu Jin

Machine learning applications that are implemented with spike-based computation model, e.g., Spiking Neural Network (SNN), have a great potential to lower the energy consumption when they are executed on a neuromorphic hardware. However,…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-13 Shihao Song , Adarsha Balaji , Anup Das , Nagarajan Kandasamy , James Shackleford

The computational problem of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype assembly, and consists in assigning all heterozygous Single Nucleotide Polymorphisms (SNPs) to exactly one of the…

Purpose: Compressed sensing MRI (CS-MRI) from single and parallel coils is one of the powerful ways to reduce the scan time of MR imaging with performance guarantee. However, the computational costs are usually expensive. This paper aims to…

Computer Vision and Pattern Recognition · Computer Science 2017-03-06 Dongwook Lee , Jaejun Yoo , Jong Chul Ye

The recent framework of compressive statistical learning aims at designing tractable learning algorithms that use only a heavily compressed representation-or sketch-of massive datasets. Compressive K-Means (CKM) is such a method: it…

Machine Learning · Computer Science 2018-08-01 Vincent Schellekens , Laurent Jacques

Motivation: Protein-to-genome alignment is critical to annotating genes in non-model organisms. While there are a few tools for this purpose, all of them were developed over ten years ago and did not incorporate the latest advances in…

Genomics · Quantitative Biology 2022-12-29 Heng Li

Metagenome assembly is the process of transforming a set of short, overlapping, and potentially erroneous DNA segments from environmental samples into the accurate representation of the underlying microbiomes's genomes. State-of-the-art…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-20 Evangelos Georganas , Rob Egan , Steven Hofmeyr , Eugene Goltsman , Bill Arndt , Andrew Tritt , Aydin Buluc , Leonid Oliker , Katherine Yelick

The Nystrom method has been popular for generating the low-rank approximation of kernel matrices that arise in many machine learning problems. The approximation quality of the Nystrom method depends crucially on the number of selected…

Machine Learning · Statistics 2016-12-21 Farhad Pourkamali-Anaraki , Stephen Becker

The Shortest Common Superstring (SCS) problem is a fundamental task in sequence analysis. In genome assembly, however, the double-stranded nature of DNA implies that each fragment may occur either in its original orientation or as its…

Data Structures and Algorithms · Computer Science 2026-03-30 Ryosuke Yamano , Tetsuo Shibuya

Sequence segmentation is a well-studied problem, where given a sequence of elements, an integer K, and some measure of homogeneity, the task is to split the sequence into K contiguous segments that are maximally homogeneous. A classic…

Data Structures and Algorithms · Computer Science 2019-02-12 Nikolaj Tatti

Estimating the number of clusters (K) is a critical and often difficult task in cluster analysis. Many methods have been proposed to estimate K, including some top performers using resampling approach. When performing cluster analysis in…

Methodology · Statistics 2019-09-05 Yujia Li , Xiangrui Zeng , Chien-Wei Lin , George Tseng

Sequential pattern mining (SPM) has excellent prospects and application spaces and has been widely used in different fields. The non-overlapping SPM, as one of the data mining techniques, has been used to discover patterns that have…

Databases · Computer Science 2023-04-25 Zefeng Chen , Wensheng Gan , Gengsen Huang , Yan Li , Zhenlian Qi

Subgraph matching is a fundamental problem in graph analysis with a wide range of applications. However, due to its inherent NP-hardness, enumerating subgraph matches efficiently on large real-world graphs remains highly challenging. Most…

Databases · Computer Science 2026-03-11 Linglin Yang , Xunbin Su , Lei Zou , Xiangyang Gou , Yinnian Lin

This paper describes the adaptation of a well-scaling parallel algorithm for computing Morse-Smale segmentations based on path compression to a distributed computational setting. Additionally, we extend the algorithm to efficiently compute…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-09 Michael Will , Jonas Lukasczyk , Julien Tierny , Christoph Garth
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