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We use a lattice model of a ternary mixture containing saturated and unsaturated lipids with cholesterol (Chol), to study the structural properties characterizing the coexistence between the liquid-disordered and liquid-ordered phases.…

Soft Condensed Matter · Physics 2023-10-24 Tanmoy Sarkar , Oded Farago

Fluid flow through layered materials with different wetting behavior is observed in a wide range of applications in biological, environmental and technical systems. Therefore, it is necessary to understand the occuring transport mechanisms…

Fluid Dynamics · Physics 2022-02-01 Cynthia Michalkowski , Kilian Weishaupt , Veronika Schleper , Rainer Helmig

Cellular membranes exhibit a large variety of shapes, strongly coupled to their function. Many biological processes involve dynamic reshaping of membranes, usually mediated by proteins. This interaction works both ways: while proteins…

Soft Condensed Matter · Physics 2018-06-12 Afshin Vahid , Anđela Šarić , Timon Idema

We study the effect of the molecular architecture of amphiphilic star polymers on the shape of aggregates they form in water. Both solute and solvent are considered at a coarse-grained level by means of dissipative particle dynamics…

Soft Condensed Matter · Physics 2017-03-31 O. Y. Kalyuzhnyi , J. M. Ilnytskyi , C. von Ferber

Confinement strongly influences electrochemical systems, where structural control has enabled advances in nanofluidics, sensing, and energy storage. In electric double-layer capacitors (EDLCs), or supercapacitors, energy density is governed…

Chemical Physics · Physics 2026-01-30 Bryce Rives , Filipe Henrique , Pawel Zuk , Ankur Gupta

Hydrogels which are hydrophilic and porous materials have recently emerged as promising systems for filtration applications. In our study, we prepare hydrogel membranes by the photopolymerization of a mixture of poly (ethylene glycol)…

We investigated the X-ray scattering signal of highly aligned multilayers of the zwitterionic lipid 1,2-dilauroyl-sn-glycero-3-phosphatidylcholine containing pores formed by the antimicrobial peptide gramicidin as a function of the…

Soft Condensed Matter · Physics 2015-04-08 Doru Constantin

Boundary lubrication is associated with two sliding molecularly thin lubricated film-coated surfaces, where the energy dissipation occurs at the slip-plane between lubricated films. The hydration lubrication paradigm, which accounts for…

Soft Condensed Matter · Physics 2022-05-20 Weifeng Lin , Nir Kampf , Jacob Klein

The response of lipid bilayers to osmotic stress is an important part of cellular function. Previously, in [Oglecka et al. 2014], we reported that cell-sized giant unilamellar vesicles (GUVs) exposed to hypotonic media, respond to the…

Biological Physics · Physics 2017-05-03 Morgan Chabanon , James C. S. Ho , Bo Liedberg , Atul N. Parikh , Padmini Rangamani

The biological function of membranes is closely related to their softness, which is often studied through the membranes' thermally-driven fluctuations. The analysis commonly assumes that the relaxation rate of a pure bending deformation is…

Soft Condensed Matter · Physics 2024-07-09 Hammad A. Faizi , Rony Granek , Petia M. Vlahovska

Lipid bilayers often form high-curvature configurations due to self-assembly conditions or certain biological processes. However, particle-based simulations of lipid membranes are predominantly of flat lipid membranes because planar…

Soft Condensed Matter · Physics 2025-01-31 James Tallman , Antonia Statt

Liquid-liquid phase separation of intrinsically disordered proteins (IDPs) is a major undergirding factor in the regulated formation of membraneless organelles in the cell. The phase behavior of an IDP is sensitive to its amino acid…

Biomolecules · Quantitative Biology 2022-01-11 Yi-Hsuan Lin , Hue Sun Chan

The cell membrane is inherently asymmetric and heterogeneous in its composition, a feature that is crucial for its function. Using atomistic molecular dynamics simulations, the physical properties of a 3-component asymmetric mixed lipid…

Soft Condensed Matter · Physics 2012-04-04 Anirban Polley , Satyavani Vemparala , Madan Rao

We model cyclic voltammetry experiments on supported lipid films where a non-trivial dependence of the capacitance on the applied voltage is observed. Previously, based on a mean-field treatment of the Flory-Huggins type, under the…

Soft Condensed Matter · Physics 2010-07-28 Andrey V. Brukhno , Anna Akinshina , Zachary Coldrick , Andrew Nelson , Stefan Auer

Free volume pockets or voids are important to many biological processes in cell membranes. Free volume fluctuations are a prerequisite for diffusion of lipids and other macromolecules in lipid bilayers. Permeation of small solutes across a…

Soft Condensed Matter · Physics 2009-11-10 Emma Falck , Michael Patra , Mikko Karttunen , Marja T. Hyvonen , Ilpo Vattulainen

In biological membranes, alpha-tocopherols ({\alpha}-toc; vitamin E) protect polyunsaturated lipids from free radicals. Although the interactions of {\alpha}-toc with non-oxidized lipid bilayers have been studied, their on oxidized bilayers…

Biological Physics · Physics 2017-04-05 Phansiri Boonnoy , Mikko Karttunen , Jirasak Wong-ekkabut

Bio-conjugated nanomaterials play a promising role in the development of novel supramolecular structures, molecular machines, and biosensing devices. In this study, lipid-conjugated gold nanoparticles were synthesized and allowed to form a…

Materials Science · Physics 2012-07-24 Subhasish Chatterjee , Markrete Krikorian , Harry D. Gafney , Bonnie Gersten

Sterols have been ascribed a major role in the organization of biological membranes, in particular for the formation of liquid ordered domains in complex lipid mixtures. Here, we employed molecular dynamics simulations to compare the…

Biological Physics · Physics 2021-07-13 Azadeh Alavizargar , Fabian Keller , R. Wedlich-Söldner , Andreas Heuer

Evaporation alters the molecular interactions and leads to phase separation within the evaporating liquid. The question of whether evaporation could lead to specific phase separation at the liquid interface and eventually to the formation…

Soft Condensed Matter · Physics 2024-08-27 Vahid Nasirimarekani

Membrane shape fluctuations induce attractive interactions between rigid inclusions. Previous analytical studies showed that the fluctuation-induced pair interactions are rather small compared to thermal energies, but also that multi-body…

Soft Condensed Matter · Physics 2009-11-07 Thomas R Weikl
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