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Semi monolithic detector designs with a series of stacked thin monolithic scintillator plates and side readout are an attractive approach for potentially achieving very high performance in a positron emission tomography (PET) scanner. In…

Instrumentation and Detectors · Physics 2025-02-12 Shiv K. Subedi , Simon R. Cherry , Yi Qiang , Peng Peng

We have developed a position-sensitive scintillation camera with a large area absorber for use as an advanced Compton gamma-ray camera. At first we tested GSO(Ce) crystals. We compared light output from the GSO(Ce) crystals under various…

Astrophysics · Physics 2008-11-26 H. Nishimura , K. Hattori , H. Kubo , T. Tanimori

Total-Body PET (TB-PET) scanners represent a significant advancement in medical diagnostics, exemplified by the uEXPLORER, the world's first TB-PET system with an axial span of 194 cm, which exhibits exceptional sensitivity and spatial…

Instrumentation and Detectors · Physics 2025-04-10 D. Choudhary , S. Nag

Objective. This study investigates the best achievable performance of a brain-dedicated PET system with high resolution and sensitivity by evaluating different detector configurations, while maintaining a practical system design suitable…

Medical Physics · Physics 2026-02-26 Yuemeng Feng , Lisa Blackberg , Arkadiusz Sitek , Hamid Sabet

Parallel hole collimators which are currently routinely used in SPECT imaging were designed a few decades ago, when filtered backprojection (FBP) was used for tomographic reconstruction. Statistical reconstruction methods with precise…

Medical Physics · Physics 2018-07-02 Krzysztof Kacperski , Dominika Świtlik , Jakub Pietrzak

Single Photon Emission Computed Tomography (SPECT) is a non-invasive imaging modality, frequently used in myocardial perfusion imaging. The biggest challenges facing the majority of clinical SPECT systems are low sensitivity, poor…

Medical Physics · Physics 2021-03-30 Narayan Bhusal

Over the last decade one of the most significant technological advances made in the field of radiation detectors for nuclear medicine was the development of Silicon Photomultipler (SiPM) sensors. At present a only small number of SiPM based…

Instrumentation and Detectors · Physics 2020-08-03 Jeremy M. C. Brown

The Integrating Miniature Piggyback for Impulsive Solar Hard X-rays (IMPISH) is a solar X-ray spectrometer that features large-area scintillators, fast readout electronics, and good energy resolution in the hard X-ray band. IMPISH is a…

This study demonstrates the feasibility of a novel fabrication technique for high spatial resolution CsI: Tl scintillation detectors tailored for single photon emission computed tomography (SPECT) systems. Building upon our previously…

Medical Physics · Physics 2026-02-16 Xi Zhang , Arkadiusz Sitek , Lisa Blackberg , Matthew Kupinski , Lars Furenlid , Hamid Sabet

A high sensitivity Cardiac SPECT system using curved crystals with pinhole collimation was proposed previously (Dey, IEEE TNS 2012, Bhusal et al, Med. Phys. 2019). Here, we hypothesize that a high curvature hemi-ellipsoid detector results…

Instrumentation and Detectors · Physics 2022-05-24 Hanif R. Soysal , J. Dey , W. P. Donahue , K. L. Matthews

Single Photon Emission Computed Tomography (SPECT) scanners based on photomultiplier tubes (PMTs) are still largely employed in the clinical environment. A standard camera for full-body SPECT employs $\sim50$-100 PMTs of 4-8~cm diameter and…

Instrumentation and Detectors · Physics 2021-03-01 D. Guberman , R. Paoletti , A. Rugliancich , C. Wunderlich , A. Passeri

A systematic study is conducted to understand the coincident resolving time (CRT) for a pair of Lutetium-yttrium oxyorthosilicate (LYSO) and the plastic scintillation detector bars under the Geant4 framework. Crystals are coupled to a…

Instrumentation and Detectors · Physics 2025-10-17 Davinder Siwal , P. K. Mohanty , D. Bose , A. Jain

Preclinical research and organ-dedicated applications require high-resolution positron emission tomography (PET) detectors to visualize small structures and understand biological processes at a finer level of detail. Current commercial…

Organ-specific, targeted Field-of-View (FoV) Positron Emission Tomography (PET)/Magnetic Resonance Imaging (MRI) inserts are viable solutions for a number of imaging tasks where whole-body PET/MRI systems lack the necessary sensitivity and…

Instrumentation and Detectors · Physics 2019-09-19 J. M. C. Brown , S. E. Brunner , D. R. Schaart

Presice measurements of the photons conversion points in the scintillators are required to achieve a high spatial resolution of the PET system. I have developed a new method of reconstruction of the depth-of-interaction information for PET…

Instrumentation and Detectors · Physics 2018-05-18 Andrei Yu. Semenov

Liquid xenon time projection chambers offer a homogeneous detection medium with excellent intrinsic energy resolution, fast scintillation, and true three-dimensional position sensitivity, making them an attractive alternative to…

Instrumentation and Detectors · Physics 2026-03-30 B. Li , Y. Ma , K. Ni

Current clinical PET systems utilize detectors where the scintillator typically contains single elements of 3 - 6 mm width and about 20 mm height. While providing good TOF performance, this design limits the spatial resolution and causes…

Instrumentation and Detectors · Physics 2022-11-17 Florian Mueller , Stephan Naunheim , Yannick Kuhl , David Schug , Torsten Solf , Volkmar Schulz

Computational spectrometers are pivotal in enabling low-cost, in-situ and rapid spectral analysis, with potential applications in chemistry, biology, and environmental science. However, filter-based spectral encoding approaches typically…

The main challenges posed by the design of future Positron Emission Tomography machines are the improvement of the spatial and timing resolution and the combined operation with magnetic resonance. The Micro Pixel Photon Counter by Hamamatsu…

Medical Physics · Physics 2008-05-06 N. D'Ascenzo , E. Garutti , M. Goettlich , H. C. Schultz-Coulon , A. Tadday
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