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Monte Carlo simulations are increasingly used in scintigraphic imaging to model imaging systems and to develop and assess tomographic reconstruction algorithms and correction methods for improved image quantitation. GATE (GEANT 4…

Instrumentation and Detectors · Physics 2009-11-10 D. Lazaro , I. Buvat , G. Loudos , D. Strul , G. Santin , N. Giokaris , D. Donnarieix , L. Maigne , V. Spanoudaki , S. Styliaris , S. Staelens , V. Breton

The Mid-infrared ELT Imager and Spectrograph (METIS) is a first-generation instrument for the Extremely Large Telescope (ELT), Europe's next-generation 39 m ground-based telescope for optical and infrared wavelengths. METIS will offer…

This paper describes the characterization of crystal matrices and silicon photomultiplier arrays for a novel Positron Emission Tomography (PET) detector, namely the external plate of the EndoTOFPET-US system. The EndoTOFPET-US collaboration…

The integration of PET into MRI to form a hybrid system requires often compromises for both subsystems. For example, the integration might come at the cost of a reduced PET detector height or a reduced MRI examination volume diameter. Here,…

Monte Carlo simulation plays an important role in the study of time of flight (TOF) positron emission tomography (PET) prototype. As it can incorporate accurate physical modeling of scintillation detection process, from scintillation light…

Instrumentation and Detectors · Physics 2013-09-17 Ze Chen , Zheng-Guo Hu , Jin-Da Chen , Xiu-Ling Zhang , Zhi-Yu Sun , Wen-Xue Huang , Jian-Song Wang , Zhong-Yan Guo , Guo-Qing Xiao

In this study, we introduce a Compton SPECT system for whole-body imaging of Actinium-225 (225Ac), one of the trending radionuclides for targeted alpha therapy (TAT). The Compton SPECT system enables multi-energy gamma photon detection with…

Medical Physics · Physics 2025-06-23 Yuemeng Feng , Arkadiusz Sitek , Shadi Abdar Esfahani , Hamid Sabet

The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…

Medical Physics · Physics 2012-03-23 A. Miceli , J. Glister , A. Andreyev , D. Bryman , L. Kurchaninov , P. Lu , A. Muennich , F. Retiere , V. Sossi

The ClearMind project aims to develop a TOF-PET position-sensitive detection module optimized for time and spatial resolutions and detection efficiency. For this, we use a 59 mm $\times$ 59 mm $\times$ 5 mm monolithic PbWO$_4$ (PWO)…

Instrumentation and Detectors · Physics 2024-06-28 A. Galindo-Tellez , V. Sharyy , C. -H. Sung , M. Follin , L. Cappellugola , S. Curtoni , M. Dupont , C. Morel , D. Breton , J. Maalmi , D. Yvon

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

This master thesis presents a new type of Positron Emission TOF Apparatus using Liquid xenOn (PETALO). The detector is based in the Liquid Xenon Scintillating Cell (LXSC). The cell is a box filled with liquid xenon (LXe) whose transverse…

Medical Physics · Physics 2016-06-01 J. M. Benlloch-Rodriguez

A PET scanner based on silicon photomultipliers (SiPMs) has been widely used as an advanced nuclear medicine imaging technique that yields quantitative images of regional in vivo biology and biochemistry. The compact size of the SiPM allows…

Instrumentation and Detectors · Physics 2022-02-02 Cong Ma , Xiaokun Zhao , Size Gao , Fengping Zhang , Guocheng Wu , Xing Li , Lei Lu , Hongwei Ye , Hua Qian

Total Body PET (TBPET) scanners have the potential to substantially reduce both acquisition time and administered radiation dose, owing to their high sensitivity. However, their widespread clinical adoption is hindered by the high cost of…

Depth-of-interaction (DOI) encoding is an effective strategy for reducing parallax error and preserving spatial resolution in positron emission tomography (PET), particularly in compact small-animal scanners. To enable efficient…

Medical Physics · Physics 2026-03-10 Satzhan Sitmukhambetov , Junwei Du , Mingwu Jin , Yujie Chi

In order to develop a high spatial resolution (micron level) thermal neutron detector, a detector assembly composed of cerium doped lithium glass microfibers, each with a diameter of 1\,$\mu$m, is proposed, where the neutron absorption…

Instrumentation and Detectors · Physics 2016-06-14 Song Yushou , Joseph Conner , Xiaodong Zhang , Jason P. Hayward

A novel design for an inexpensive depth of interaction capable detector for gamma rays, suitable for nuclear medical applications, especially Positron Emission Tomography, has been developed. The design takes advantage of the strong…

Medical Physics · Physics 2009-09-29 Christoph W. Lerche

The VLTI Spectro Imager project aims to perform imaging with a temporal resolution of 1 night and with a maximum angular resolution of 1 milliarcsecond, making best use of the Very Large Telescope Interferometer capabilities. To fulfill the…

In this work, we present modeling and imaging performance of a dual panel limited-angle TOF-PET system for intraoperative surgical applications using GATE monte carlo toolkit. Several detector parameters such as detector pixel dimensions,…

Medical Physics · Physics 2024-02-13 Salar Sajedi , Yuemeng Feng , Hamid Sabet

Inter-crystal scattering (ICS) in Positron Emission Tomography (PET) is commonly regarded as a degradation effect that might compromise the image spatial resolution. In parallel, the inclusion of ICS events has also been recognized as a…

Medical Physics · Physics 2026-05-12 Jorge Roser , Hong Phuc Vo , Rebecca Kantorek , Steven Seeger , Magdalena Rafecas

The concept for space interferometry from Polar or Equatorial Circular Medium Earth Orbits (the PECMEO concept) is a promising way to acquire the image of the "shadow" of the event horizon of Sagittarius A* with an angular resolution of…

Instrumentation and Methods for Astrophysics · Physics 2021-05-17 V. Kudriashov , M. Martin-Neira , I. Barat , P. Martin Iglesias , E. Daganzo-Eusebio , N. Alagha , V. Valenta

The Mid-infrared ELT Imager and Spectrograph (METIS) will provide the Extremely Large Telescope (ELT) with a unique window to the thermal- and mid-infrared (3 - 13 microns). Its single-conjugate adaptive optics (SCAO) system will enable…