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We present the photometric performance of SPIRIT, a ground-based near-infrared InGaAs CMOS-based instrument (1280 by 1024 pixels, 12 micron pitch), using on-sky results from the SPECULOOS-Southern Observatory during 2022 - 2023. SPIRIT was…

Intraoperative Gamma Probe (IPG) remains the current gold standard modality for sentinel lymph node identification and tumor removal in cancer patients. However, even alongside the optical dyes they do not meet with <5% false negative rates…

Medical Physics · Physics 2022-01-26 S. Sajedi , L. Blackberg , S. Majewski , H. Sabet

A sparsity-exploiting algorithm intended for few-view Single Photon Emission Computed Tomography (SPECT) reconstruction is proposed and characterized. The algorithm models the object as piecewise constant subject to a blurring operation. To…

Medical Physics · Physics 2012-12-05 Paul A Wolf , Jakob H Jørgensen , Taly G Schmidt , Emil Y Sidky

PET provides in vivo molecular and functional imaging capability that is crucial to studying the interaction of plant with changing environment at the whole-plant level. We have developed a dedicated plant PET imager that features high…

Instrumentation and Detectors · Physics 2014-09-22 Qiang Wang , Aswin J. Mathews , Ke Li , Jie Wen , Sergey Komarov , Joseph A. O'Sullivan , Yuan-Chuan Tai

Total Body PET (TBPET) scanners have recently demonstrated the ability to significantly reduce both acquisition time and the administered radioactive dose, thanks to their increased sensitivity. However, their widespread adoption is limited…

Instrumentation and Detectors · Physics 2025-06-25 S. R. Soleti , A. Castillo , J. I. Collar , M. del Barrio-Torregrosa , C. Echeverria , M. Seemann , D. Zerzion , J. J. Gómez Cadenas

We report on the measurements performed using a 22Na source on a detector element for an MRI-compatible TOF-PET endorectal prostate probe, with Depth-Of-Interaction sensitivity. It is made from a LYSO scintillator crystal, wrapped with…

Instrumentation and Detectors · Physics 2015-06-11 Luigi Cosentino , Paolo Finocchiaro , Alfio Pappalardo , Franco Garibaldi

We describe the design, construction and commissioning of LOTUS; a simple, low-cost long-slit spectrograph for the Liverpool Telescope. The design is optimized for near-UV and visible wavelengths and uses all transmitting optics. It…

Instrumentation and Methods for Astrophysics · Physics 2016-06-08 I. A. Steele , J. M. Marchant , H. E. Jermak , R. M. Barnsley , S. D. Bates , N. R. Clay , A. Fitzsimmons , E. Jehin , G. Jones , C. J. Mottram , R. J. Smith , C. Snodgrass , M. de Val-Borro

Speckled illumination enhances widefield fluorescence microscopy by enabling optical sectioning and super resolution. In random illumination microscopy, sequences of speckled illumination patterns are used to excite fluorescent samples and…

Using the 1-BM-C beamline at the Advanced Photon Source (APS), we have performed the initial indirect x-ray imaging point-spread-function (PSF) test of a unique 88-mm diameter YAG:Ce single crystal of only 100-micron thickness. The crystal…

Accelerator Physics · Physics 2017-09-15 A. H. Lumpkin , A. T. Macrander

The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…

Instrumentation and Detectors · Physics 2016-10-12 J. J Gomez-Cadenas , J. M. Benlloch-Rodríguez , P. Ferrario , F. Monrabal , J. Rodríguez , J. F. Toledo

Scintillating homogeneous detectors represent the state of the art in electromagnetic calorimetry. Moreover, the currently neglected crystalline nature of the most common inorganic scintillators can be exploited to achieve an outstanding…

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

This study presents a comprehensive end-to-end simulation analysis of the optical imaging performance of the China Survey Space Telescope (CSST) under in-orbit conditions. An integrated system model incorporating five static and two dynamic…

Instrumentation and Methods for Astrophysics · Physics 2025-11-11 Zhang Ban , Xiao-Bo Li , Xun Yang , Yu-Xi Jiang , Hong-Cai Ma , Wei Wang , Jin-guang Lv , Cheng-Liang Wei , De-Zi Liu , Guo-Liang Li , Chao Liu , Nan Li , Ran Li , Peng Wei

We are investigating a prototype virtual pinhole positron emission tomography (VP-PET) system for small animal imaging applications. The PET detector modules were made up of 1.3 mm lutetium-yttrium oxyorthosilicate (LYSO) arrays, and the…

Medical Physics · Physics 2018-01-11 Zheng-Qian Ye , Ying-Guo Li , Tian-Quan Wang , Ya-Ming Fan , Yong-Zhi Yin , Xi-Meng Chen

The quality of SPECT Bremsstrahlung images of patients treated with Y-90 is poor, mainly because of scattered radiation and collimator septa penetration. To minimize the latter effect, High Energy (HE) or Medium Energy (ME) collimators can…

In the context of a localization and tracking application, we developed a stereo vision system based on cheap low-resolution 80x60 pixels thermal cameras. We proposed a threefold sub-pixel stereo matching framework (called ST for Subpixel…

Computer Vision and Pattern Recognition · Computer Science 2019-12-03 Yannick Wend Kuni Zoetgnande , Geoffroy Cormier , Alain-Jérôme Fougères , Jean-Louis Dillenseger

Optical spectrometers are widely used scientific equipment with many applications involving material characterization, chemical analysis, disease diagnostics, surveillance, etc. Emerging applications in biomedical and communication fields…

Miniaturized spectrometers employing chip solutions are essential for a wide range of applications, such as wearable health monitoring, biochemical sensing, and portable optical coherence tomography. However, the development of integrated…

Optics · Physics 2025-05-22 Wenzhang Tian , Hao Chen , Mingyuan Zhang , Zengqi Chen , Yeyu Tong

The optimization of silicon photodiode-based CMOS sensors with backside-illumination for 300-1000 nm wavelength range was studied. It was demonstrated that a single hole on a photodiode increases the optical efficiency of the pixel in…

A high-granularity crystal calorimeter (HGCCAL) has been proposed for the future Circular Electron Positron Collider (CEPC). This study investigates the time resolution of various crystal - Silicon Photomultiplier (SiPM) detection units for…

Instrumentation and Detectors · Physics 2025-03-24 Zhiyu Zhao , Dejing Du , Yong Liu , Jiyuan Chen , Junfeng Chen , Fangyi Guo , Shu Li , Baohua Qi