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Sequence alignment is a fundamental process in computational biology which identifies regions of similarity in biological sequences. With the exponential growth in the volume of data in bioinformatics databases, the time, processing power,…

Hardware Architecture · Computer Science 2025-07-31 Nasrin Akbari , Mehdi Modarressi , Alireza Khadem

Evaluating the computational reproducibility of data analysis pipelines has become a critical issue. It is, however, a cumbersome process for analyses that involve data from large populations of subjects, due to their computational and…

Methodology · Statistics 2018-09-28 Soudabeh Barghi , Lalet Scaria , Ali Salari , Tristan Glatard

The denoising diffusion probabilistic model has become a mainstream generative model, achieving significant success in various computer vision tasks. Recently, there has been initial exploration of applying diffusion models to time series…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Yuxuan Chen , Haipeng Xie

Joint modeling has become increasingly popular for characterizing the association between one or more longitudinal biomarkers and competing risks time-to-event outcomes. However, semiparametric multivariate joint modeling for large-scale…

Methodology · Statistics 2025-06-17 Shanpeng Li , Emily Ouyang , Jin Zhou , Xinping Cui , Gang Li

Near term quantum computers suffer from the presence of different noise sources. In order to mitigate for this effect and acquire results with significantly better accuracy, there is the urge of designing efficient error correction or error…

It is well known that the integration among different data-sources is reliable because of its potential of unveiling new functionalities of the genomic expressions which might be dormant in a single source analysis. Moreover, different…

Methodology · Statistics 2021-12-08 Arnab Kumar Maity , Sang Chan Lee , Bani K. Mallick , Tapasree Roy Sarkar

Four decades after Richard Feynman's famous remark, we have reached a stage at which nature can be simulated quantum mechanically. Quantum simulation is among the most promising applications of quantum computing. However, like many quantum…

Quantum Physics · Physics 2026-02-17 Mahmood Hasani , Hadis Salasi , Negar Ashari Astani

Quantum computers represent a radical technological advancement in the way information is processed by using the principles of quantum mechanics to solve very complex problems that exceed the capabilities of classical systems. However, in…

Quantum Physics · Physics 2025-08-28 Marcos Guillermo Lammers , Federico Hernán Holik , Alejandro Fernández

The successful implementation of algorithms on quantum processors relies on the accurate control of quantum bits (qubits) to perform logic gate operations. In this era of noisy intermediate-scale quantum (NISQ) computing, systematic…

Modern IT system operation demands the integration of system software and hardware metrics. As a result, it generates a massive amount of data, which can be potentially used to make data-driven operational decisions. In the basic form, the…

Machine Learning · Computer Science 2022-11-16 Jiajia Li , Feng Tan , Cheng He , Zikai Wang , Haitao Song , Lingfei Wu , Pengwei Hu

Next-generation sequencing technologies provide a revolutionary tool for generating gene expression data. Starting with a fixed RNA sample, they construct a library of millions of differentially abundant short sequence tags or "reads",…

Quantitative Methods · Quantitative Biology 2014-05-13 Dimitrios V. Vavoulis , Julian Gough

With the advent of Big Data, nowadays in many applications databases containing large quantities of similar time series are available. Forecasting time series in these domains with traditional univariate forecasting procedures leaves great…

Machine Learning · Computer Science 2018-09-13 Kasun Bandara , Christoph Bergmeir , Slawek Smyl

Sequential models, such as Recurrent Neural Networks and Neural Ordinary Differential Equations, have long suffered from slow training due to their inherent sequential nature. For many years this bottleneck has persisted, as many thought…

Machine Learning · Computer Science 2024-01-17 Yi Heng Lim , Qi Zhu , Joshua Selfridge , Muhammad Firmansyah Kasim

Deploying neural networks on the edge has become increasingly important as deep learning is being applied in an increasing amount of applications. At the edge computing hardware typically has limited resources disallowing to run neural…

Machine Learning · Computer Science 2025-09-15 Quinten Van Baelen , Peter Karsmakers

Large reasoning models (LRMs) excel at complex reasoning tasks but typically generate lengthy sequential chains-of-thought, resulting in long inference times before arriving at the final answer. To address this challenge, we introduce…

Artificial Intelligence · Computer Science 2025-12-04 Emil Biju , Shayan Talaei , Zhemin Huang , Mohammadreza Pourreza , Azalia Mirhoseini , Amin Saberi

Regardless of the domain, forecasting the future behaviour of a running process instance is a question of interest for decision makers, especially when multiple instances interact. Fostered by the recent advances in machine learning…

Machine Learning · Computer Science 2023-07-04 Stefan Hill , David Fitzek , Patrick Delfmann , Carl Corea

Traditional databases commonly support efficient query and update procedures that operate in time which is sublinear in the size of the database. Our goal in this paper is to take a first step toward dynamic reasoning in probabilistic…

Artificial Intelligence · Computer Science 2009-09-25 A. L. Delcher , A. J. Grove , S. Kasif , J. Pearl

Scientific investigations that incorporate next generation sequencing involve analyses of high-dimensional data where the need to organize, collate and interpret the outcomes are pressingly important. Currently, data can be collected at the…

Machine Learning · Statistics 2016-08-01 Stephen T Rush , Christine H Lee , Washington Mio , Peter T Kim

Recurrent neural networks are used to forecast time series in finance, climate, language, and from many other domains. Reservoir computers are a particularly easily trainable form of recurrent neural network. Recently, a "next-generation"…

Machine Learning · Computer Science 2023-03-28 Sarah E. Marzen , Paul M. Riechers , James P. Crutchfield

Quantum computing offers new ways to explore the theory of computation via the laws of quantum mechanics. Due to the rising demand for quantum computing resources, there is growing interest in developing cloud-based quantum resource sharing…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-07 Irwindeep Singh , Sukhpal Singh Gill , Jinzhao Sun , Jan Mol