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Scientific imaging often involves long acquisition times to obtain high-quality data, especially when probing complex, heterogeneous systems. However, reducing acquisition time to increase throughput inevitably introduces significant noise…

Artificial Intelligence · Computer Science 2025-05-14 Petrus H. Zwart , Tamas Varga , Odeta Qafoku , James A. Sethian

Recently, there has been a resurgence of interest in rigorous algorithms for the inference of cancer progression from genomic data. The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel…

Machine Learning · Computer Science 2016-02-25 Daniele Ramazzotti

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

Motivation: Traditional computational cluster schedulers are based on user inputs and run time needs request for memory and CPU, not IO. Heavily IO bound task run times, like ones seen in many big data and bioinformatics problems, are…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-12-27 Christopher Harrison , Christine R. Kirkpatrick , Inês Dutra

Recurrent neural networks are a powerful tool for modeling sequential data, but the dependence of each timestep's computation on the previous timestep's output limits parallelism and makes RNNs unwieldy for very long sequences. We introduce…

Neural and Evolutionary Computing · Computer Science 2016-11-22 James Bradbury , Stephen Merity , Caiming Xiong , Richard Socher

Equation learning methods present a promising tool to aid scientists in the modeling process for biological data. Previous equation learning studies have demonstrated that these methods can infer models from rich datasets, however, the…

Since the arrival of next-generation sequencing technologies the amount of genetic sequencing data has increased dramatically. This has has fueled an increase in human genetics research. At the same time, with the recent advent of…

Genomics · Quantitative Biology 2016-07-04 Kristiina Ausmees , Pushpam Aji John

The combination of machine learning and quantum computing has emerged as a promising approach for addressing previously untenable problems. Reservoir computing is an efficient learning paradigm that utilizes nonlinear dynamical systems for…

Quantum Physics · Physics 2020-08-26 Jiayin Chen , Hendra I. Nurdin , Naoki Yamamoto

Innovations in Next-Generation Sequencing are enabling generation of DNA sequence data at ever faster rates and at very low cost. Large sequencing centers typically employ hundreds of such systems. Such high-throughput and low-cost…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-07-31 Vasimuddin Md , Sanchit Misra , Heng Li , Srinivas Aluru

Radio Resource Management is a challenging topic in future 6G networks where novel applications create strong competition among the users for the available resources. In this work we consider the frequency scheduling problem in a multi-user…

Networking and Internet Architecture · Computer Science 2024-12-18 Anastasios Giovanidis , Mathieu Leconte , Sabrine Aroua , Tor Kvernvik , David Sandberg

Modern machine learning models are typically trained using Stochastic Gradient Descent (SGD) on massively parallel computing resources such as GPUs. Increasing mini-batch size is a simple and direct way to utilize the parallel computing…

Machine Learning · Statistics 2019-03-05 Siyuan Ma , Mikhail Belkin

We propose a Quantum Machine Learning (QML) framework that leverages quantum parallelism to process entire training datasets in a single quantum operation, addressing the computational bottleneck of sequential data processing in both…

DNA is a promising medium for digital information storage for its exceptional density and durability. While prior studies advanced coding theory, workflow design, and simulation tools, challenges such as synthesis costs, sequencing errors,…

Emerging Technologies · Computer Science 2025-10-06 Rakesh Thakur , Lavanya Singh , Yashika , Manomay Bundawala , Aruna Kumar

Real-world time series data often exhibits substantial missing values, posing challenges for advanced analysis. A common approach to addressing this issue is imputation, where the primary challenge lies in determining the appropriate values…

Machine Learning · Computer Science 2025-12-02 Ying Liu , Peng Cui , Wenbo Hu , Richang Hong

Many bioinformatics problems, such as sequence alignment, gene prediction, phylogenetic tree estimation and RNA secondary structure prediction, are often affected by the "uncertainty" of a solution; that is, the probability of the solution…

Quantitative Methods · Quantitative Biology 2013-05-17 Michiaki Hamada

The increased availability of massive data sets provides a unique opportunity to discover subtle patterns in their distributions, but also imposes overwhelming computational challenges. To fully utilize the information contained in big…

Statistics Theory · Mathematics 2018-04-12 Stanislav Volgushev , Shih-Kang Chao , Guang Cheng

The increasing focus on long-term time series prediction across various fields has been significantly strengthened by advancements in quantum computation. In this paper, we introduce a data-driven method designed for time series prediction…

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

Symbolic representations of time series have proven to be effective for time series classification, with many recent approaches including SAX-VSM, BOSS, WEASEL, and MrSEQL. The key idea is to transform numerical time series to symbolic…

Machine Learning · Computer Science 2022-03-16 Thach Le Nguyen , Georgiana Ifrim

Speculative inference is a promising paradigm employing small speculative models (SSMs) as drafters to generate draft tokens, which are subsequently verified in parallel by the target large language model (LLM). This approach enhances the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-16 Luyao Gao , Jianchun Liu , Hongli Xu , Xichong Zhang , Yunming Liao , Liusheng Huang
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