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The ability to maintain and manipulate information over time is a fundamental aspect of living beings and Artificial Intelligence. While modern models have achieved remarkable success in tasks like natural language processing, evaluating…

Artificial Intelligence · Computer Science 2026-05-20 Yannis Bendi-Ouis , Romain de Coudenhove , Xavier Hinaut

The reproducibility of computational pipelines is an expectation in biomedical science, particularly in critical domains like human health. In this context, reporting next generation genome sequencing methods used in precision medicine…

Computational Engineering, Finance, and Science · Computer Science 2024-12-11 Meznah Aloqalaa , Stian Soiland-Reyes , Carole Goble

While sequence-to-sequence (seq2seq) models achieve state-of-the-art performance in many natural language processing tasks, they can be too slow for real-time applications. One performance bottleneck is predicting the most likely next token…

Computation and Language · Computer Science 2019-07-26 Chunyang Xiao , Christoph Teichmann , Konstantine Arkoudas

Graph Neural Networks (GNNs) are powerful tools for learning graph-structured data, but their scalability is hindered by inefficient mini-batch generation, data transfer bottlenecks, and costly inter-GPU synchronization. Existing training…

Machine Learning · Computer Science 2026-01-09 Irfan Ullah , Young-Koo Lee

Among the main features of biological intelligence are energy efficiency, capacity for continual adaptation, and risk management via uncertainty quantification. Neuromorphic engineering has been thus far mostly driven by the goal of…

Neural and Evolutionary Computing · Computer Science 2022-11-02 Nicolas Skatchkovsky , Hyeryung Jang , Osvaldo Simeone

Present-day quantum systems face critical bottlenecks, including limited qubit counts, brief coherence intervals, and high susceptibility to errors-all of which obstruct the execution of large and complex circuits. The advancement of…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-13 Waylon Luo , Jiapeng Zhao , Tong Zhan , Qiang Guan

Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

Methodology · Statistics 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

We propose a frame-based representation of k-mers for detecting sequencing errors and rare variants in next generation sequencing data obtained from populations of closely related genomes. Frames are sets of non-orthogonal basis functions,…

Genomics · Quantitative Biology 2016-04-19 Raunaq Malhotra , Manjari Mukhopadhyay , Mary Poss , Raj Acharya

Risk prediction capitalizing on emerging human genome findings holds great promise for new prediction and prevention strategies. While the large amounts of genetic data generated from high-throughput technologies offer us a unique…

Methodology · Statistics 2021-01-29 Xiaoxi Shen , Xiaoran Tong , Qing Lu

There has been tremendous progress in the physical realization of quantum computing hardware in recent times, bringing us closer than ever before to realizing the promise of quantum computing. However, noise continues to pose a crucial…

Rapidly growing public gene expression databases contain a wealth of data for building an unprecedentedly detailed picture of human biology and disease. This data comes from many diverse measurement platforms that make integrating it all…

Genomics · Quantitative Biology 2014-10-16 Karolis Uziela , Antti Honkela

Reservoir computing is a best-in-class machine learning algorithm for processing information generated by dynamical systems using observed time-series data. Importantly, it requires very small training data sets, uses linear optimization,…

Machine Learning · Computer Science 2021-09-22 Daniel J. Gauthier , Erik Bollt , Aaron Griffith , Wendson A. S. Barbosa

We present a simple and scalable implementation of next-generation reservoir computing (NGRC) for modeling dynamical systems from time-series data. The method uses a pseudorandom nonlinear projection of time-delay embedded inputs, allowing…

Machine Learning · Statistics 2026-01-12 Rok Cestnik , Erik A. Martens

Traditional machine learning methods face two main challenges in dealing with healthcare predictive analytics tasks. First, the high-dimensional nature of healthcare data needs labor-intensive and time-consuming processes to select an…

Machine Learning · Computer Science 2022-09-16 Mohammad Amin Morid , Olivia R. Liu Sheng , Joseph Dunbar

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

Stochastic Ising machines, sIMs, are highly promising accelerators for optimization and sampling of computational problems that can be formulated as an Ising model. Here we investigate the computational advantage of sIM for simulations of…

Quantum Physics · Physics 2026-03-06 Rutger J. L. F. Berns , Davi R. Rodrigues , Giovanni Finocchio , Johan H. Mentink

Deciphering cell type heterogeneity is crucial for systematically understanding tissue homeostasis and its dysregulation in diseases. Computational deconvolution is an efficient approach estimating cell type abundances from a variety of…

Other Quantitative Biology · Quantitative Biology 2023-09-06 Lana X. Garmire , Yijun Li , Qianhui Huang , Chuan Xu , Sarah Teichmann , Naftali Kaminski , Matteo Pellegrini , Quan Nguyen , Andrew E. Teschendorff

Accurate prediction of resource consumption and runtime for cloud workflow jobs is critical for scheduling efficiency, yet remains challenging due to the semi-structured nature of job configurations -- comprising shell commands,…

Machine Learning · Computer Science 2026-05-18 Yuxuan Yin , Shengke Zhou , Yunjie Zhang , Ajay Mohindra , Boxun Xu , Peng Li

The advancement of human healthspan and bioengineering relies heavily on predicting the behavior of complex biological systems. While high-throughput multiomics data is becoming increasingly abundant, converting this data into actionable…

Machine Learning · Computer Science 2025-12-10 Udesh Habaraduwa , Andrei Lixandru

Efficient task scheduling is paramount in the Linux kernel, where the Completely Fair Scheduler (CFS) meticulously manages CPU resources to balance high utilization with interactive responsiveness. This research pioneers the use of deep…

Machine Learning · Computer Science 2025-05-22 Sampanna Yashwant Kahu
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