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We demonstrate the stimulated Raman near-field microscopy of few molecules, measured only using near-field optical forces thereby eliminating the need for far-field optical detection. The molecules were excited in the near-field without…
Fluorescence detection is a commonly used analytical method with the advantages of fast response, good selectivity and low destructiveness. However, fluorescence detection, a single-mode detection method, has some limitations, such as…
We propose a new class of bosonic dark matter (DM) detectors based on resonant absorption onto a gas of small polyatomic molecules. Bosonic DM acts on the molecules as a narrow-band perturbation, like an intense but weakly coupled laser.…
Plasmonic nanopores combine nanofluidic confinement with electromagnetic field enhancement, enabling optical interrogation of single molecules in sub-wavelength volumes. Yet, direct optical readout within these metallic geometries has…
Super-resolution localization microscopy is based on determining the positions of individual fluorescent markers in a sample. The major challenge in reaching an ever higher localization precision lies in the limited number of collected…
The analysis of proteins in the gas phase benefits from detectors that exhibit high efficiency and precise spatial resolution. Although modern secondary electron multipliers already address numerous analytical requirements, new methods are…
Scattering of light by matter has been studied extensively in the past. Yet, the most fundamental process, the scattering of a single photon by a single atom, is largely unexplored [1-3]. One prominent prediction of quantum optics is the…
We experimentally demonstrate optical spectroscopy of magnetically trapped atoms on an atom chip. High resolution optical spectra of individual trapped clouds are recorded within a few hundred milliseconds. Detection sensitivities close to…
Plasmons --the collective oscillations of electrons in conducting materials-- play a pivotal role in nanophotonics because of their ability to couple electronic and photonic degrees of freedom. In particular, plasmons in graphene --the…
Nuclear radiation detectors play a key role in applications spanning nuclear and particle physics, nuclear engineering, security, and medicine. With the expanded global interest in nuclear power, discreet, inconspicuous, and readily…
Room temperature detection of molecular vibrations in the mid-infrared (MIR, $\lambda$ =3-30$\mu$m) has numerous applications including real-time gas sensing, chemical reactivity, medical imaging, astronomical surveys, and quantum…
Controllable atomic-scale quantum systems hold great potential as sensitive tools for nanoscale imaging and metrology. Possible applications range from nanoscale electric and magnetic field sensing to single photon microscopy, quantum…
Single photon detectors have historically consisted of macroscopic-sized materials but recent experimental and theoretical progress suggests new approaches based on nanoscale and molecular electronics. Here we present a theoretical study of…
Superconducting nanostrip photon detectors have been used as single photon detectors, which can discriminate only photons' presence or absence. It has recently been found that they can discriminate the number of photons by analyzing the…
We extend the Purcell's original idea [Phys. Rev. \textbf{69}, 682 (1946)] on modification of photon spontaneous \textit{emission} rate to modification of photon spontaneous \textit{scattering} rate. We find the interplay of local incident…
Nuclei detection is an important task in the histology domain as it is a main step toward further analysis such as cell counting, cell segmentation, study of cell connections, etc. This is a challenging task due to the complex texture of…
Optical mixing experiments show the ability of amplifying a weak optical signal by superposing it with a stronger one. This principle has been demonstrated also for weak signals at the quantum level, down to a single photon. In the present…
Single molecule spectroscopy aims at unveiling often hidden but potentially very important contributions of single entities to a system's ensemble response. Albeit contributing tremendously to our ever growing understanding of molecular…
We report an optical technique that yields an enhancement of single-molecule photostability, by greatly suppressing photobleaching pathways which involve photoexcitation from the triplet state. This is accomplished by dynamically switching…
Molecular-scale computation is crucial for smart materials and nanoscale devices, yet creating single-molecule systems capable of complex computations remains challenging. We present a theoretical framework for a single-molecule computer…