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We propose a new technique for the detection of single atoms in ultracold quantum gases. The technique is based on scanning electron microscopy and employs the electron impact ionization of trapped atoms with a focussed electron probe.…
Single-cell analysis can unravel functional heterogeneity within cell populations otherwise obscured by ensemble measurements. However, non-invasive techniques that probe chemical entities and their dynamics are still lacking. This…
The emission and absorption of single photons by single atomic particles is a fundamental limit of matter-light interaction, manifesting its quantum mechanical nature. At the same time, as a controlled process it is a key enabling tool for…
The ability to detect single photons has become increasingly essential due to the rise of photon-based quantum computing. In this theoretical work, we propose a system consisting of a quantum dot (QD) side-coupled to a superconducting…
A diamond nano-crystal hosting a single nitrogen vacancy (NV) center is optically selected with a confocal scanning microscope and positioned deterministically onto the subwavelength-diameter waist of a tapered optical fiber (TOF) with the…
We apply input-output theory with quantum pulses [AH Kiilerich, K M\o lmer, Phys. Rev. Lett. {\bf 123}, 123604 (2019)] to a model of a new type of two-photon detector consisting of one molecule that can detect two photons arriving…
Our results demonstrate a new method for label-free, real-time oligonucleotide characterisation by their self-resonant modes, which are unique to their conformation and sequence. We anticipate that our assay will be used as a starting point…
Recent advances in top-down mass spectrometry enabled identification of intact proteins, but this technology still faces challenges. For example, top-down mass spectrometry suffers from a lack of sensitivity since the ion counts for a…
More than twenty years ago, scientists succeeded in pushing the limits of optical detection to single molecules using fluorescence. This breakthrough has revolutionized biophysical measurements, but restrictions in photophysics and labeling…
Single photon detection generally consists of several stages: the photon has to interact with one or more charged particles, its excitation energy will be converted into other forms of energy, and amplification to a macroscopic signal must…
Integrated single photon sources are key building blocks for realizing scalable devices for quantum information processing. For such applications highly coherent and indistinguishable single photons on a chip are required. Here we report on…
Molecular combing is a powerful and simple method for aligning DNA molecules onto a surface. Using this technique combined with fluorescence microscopy, we observed that the length of lambda-DNA molecules was extended to about 1.6 times…
Further development of quantum emitter based communication and sensing applications intrinsically depends on the availability of robust single-photon detectors. Here, we demonstrate a new generation of superconducting single-photon…
Superconducting nanowire single photon detectors are capable of single-photon detection across a large spectral range, with near unity detection efficiency, picosecond timing jitter, and sub-10 $\mu$m position resolution at rates as high as…
Quantum emitters respond to resonant illumination by radiating electromagnetic fields. A component of these fields is phase-coherent with the driving tone, while another one is incoherent, consisting of spontaneously emitted photons and…
While the fundamental limit on the resolution achieved in an atomic force microscope (AFM) is clearly related to the tip radius, the fact that the tip can creep and/or wear during an experiment is often ignored. This is mainly due to the…
Single quantum emitters like atoms are well-known as non-classical light sources which can produce photons one by one at given times, with reduced intensity noise. However, the light field emitted by a single atom can exhibit much richer…
Direct observation of single-molecule interactions and dynamic configurations in situ is a demanding challenge but crucial for both chemical and biological systems. However, optical microscopy that relies on bulk measurements cannot meet…
We report the cooling of an atomic ensemble with light, where each atom scatters only a single photon on average. This is a general method that does not require a cycling transition and can be applied to atoms or molecules which are…
Single quantum emitters play a fundamental role in the development of quantum technologies such as quantum repeaters, and quantum information processing. Isolating individual molecules with stable optical emission is an essential step for…