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We study the early stages of viral infection, and the distribution of times to obtain a persistent infection. The virus population proliferates by entering and reproducing inside a target cell until a sufficient number of new virus…

Populations and Evolution · Quantitative Biology 2019-07-11 Carmel Sagi , Michael Assaf

The structure of sexual contacts, its contacts network and its temporal interactions, play an important role in the spread of sexually transmitted infections. Unfortunately, that kind of data is very hard to obtain. One of the few…

Physics and Society · Physics 2015-06-11 Alexsandro M. Carvalho , Sebastian Goncalves

This research gives a thorough examination of an HIV infection model that includes quiescent cells and immune response dynamics in the host. The model, represented by a system of ordinary differential equations, captures the complex…

Populations and Evolution · Quantitative Biology 2025-03-04 Ibrahim Nali , Attila Dénes , Abdessamad Tridane , Xueyong Zhou

In this paper, we further investigate the global dynamics of a stochastic differential equation SIS (Susceptible-Infected-Susceptible) epidemic model recently proposed in [A. Gray et al., SIAM. J. Appl. Math., 71 (2011), 876-902]. We…

Dynamical Systems · Mathematics 2016-08-24 Chuang Xu

In the framework of population dynamics, the basic reproduction number R_0 is, by definition, the expected number of offspring that an individual has during its lifetime. In constant and time periodic environments it is calculated as the…

Analysis of PDEs · Mathematics 2026-04-16 Carles Barril , Àngel Calsina , Sílvia Cuadrado , Jordi Ripoll

In contrast to the common assumption in epidemic models that the rate of infection between individuals is constant, in reality, an individual's viral load determines their infectiousness. We compare the average and individual reproductive…

Populations and Evolution · Quantitative Biology 2021-12-07 Nicholas Landry

The ordinary contact process is used to model the spread of a disease in a population. In this model, each infected individual waits an exponentially distributed time with parameter 1 before becoming healthy. In this paper, we introduce and…

Probability · Mathematics 2011-11-10 Erik I. Broman

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

Populations and Evolution · Quantitative Biology 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

Spreading from a seed is studied by Monte Carlo simulation on a square lattice with two types of sites affecting the rates of birth and death. These systems exhibit a critical transition between survival and extinction. For time- dependent…

Disordered Systems and Neural Networks · Physics 2009-11-07 Gyorgy Szabo , Hajnalka Gergely , Beata Oborny

This paper deals with a simplified SIS model, which describes the transmission of the disease in time-periodic heterogeneous environment. To understand the impact of spatial heterogeneity of environment and small advection on the…

Analysis of PDEs · Mathematics 2015-10-14 Jing Ge , Chengxia Lei , Zhigui Lin

The frog model is a stochastic model for the spreading of an epidemic on a graph, in which a dormant particle starts to perform a simple random walk on the graph and to awake other particles, once it becomes active. We study two versions of…

Probability · Mathematics 2020-01-29 Elcio Lebensztayn , Mario Andres Estrada

We consider SISI epidemic model with discrete-time. The crucial point of this model is that an individual can be infected twice. This non-linear evolution operator depends on seven parameters and we assume that the population size under…

Dynamical Systems · Mathematics 2020-08-31 Sobirjon Shoyimardonov

This paper deals with a new epidemiological model of SIRS with stochastic perturbations. The primary objective is to establish the existence of a unique non-negative nonlocal solution. Using the basic reproduction number $\mathscr{R}_0$…

Dynamical Systems · Mathematics 2025-03-10 Achraf Zinihi , Moulay Rchid Sidi Ammi , Matthias Ehrhardt

Despite the enormous relevance of zoonotic infections to world- wide public health, and despite much effort in modeling individual zoonoses, a fundamental understanding of the disease dynamics and the nature of outbreaks arising in such…

Populations and Evolution · Quantitative Biology 2013-07-18 Sarabjeet Singh , David J. Schneider , Christopher R. Myers

The susceptible-infectious-recovered (SIR) model describes the evolution of three species of individuals which are subject to an infection and recovery mechanism. A susceptible $S$ can become infectious with an infection rate $\beta$ by an…

Statistical Mechanics · Physics 2008-06-30 Gunter M. Schütz , Marian Brandau , Steffen Trimper

The stochastic extinction and stability in the mean of a family of SEIRS malaria models with a general nonlinear incidence rate is presented. The dynamics is driven by independent white noise processes from the disease transmission and…

Populations and Evolution · Quantitative Biology 2020-05-05 Divine Wanduku

We study the critical behavior of a general contagion model where nodes are either active (e.g. with opinion A, or functioning) or inactive (e.g. with opinion B, or damaged). The transitions between these two states are determined by (i)…

Physics and Society · Physics 2017-02-24 Lucas Böttcher , Jan Nagler , Hans J. Herrmann

We consider a stochastic model for a pathogen population in the presence of an immune response, in which pathogen types are partially ordered by ancestry and the immune system must eliminate ancestor types before it can eliminate their…

Probability · Mathematics 2026-02-03 Carolina Grejo , Fabio Lopes , Fábio Machado , Alejandro Roldán-Correa

This article is concerned with a version of the contact process with sexual reproduction on a graph with two levels of interactions modeling metapopulations. The population is spatially distributed into patches and offspring are produced in…

Probability · Mathematics 2015-04-08 Eric Foxall , Nicolas Lanchier

In the Susceptible-Infectious-Recovered (SIR) model of disease spreading, the time to extinction of the epidemics happens at an intermediate value of the per-contact transmission probability. Too contagious infections burn out fast in the…

Populations and Evolution · Quantitative Biology 2014-03-05 Petter Holme