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Causal processes in biomedicine may contain cycles, evolve over time or differ between populations. However, many graphical models cannot accommodate these conditions. We propose to model causation using a mixture of directed cyclic graphs…

Machine Learning · Statistics 2020-09-08 Eric V. Strobl

Learning the structure of dependence relations between variables is a pervasive issue in the statistical literature. A directed acyclic graph (DAG) can represent a set of conditional independences, but different DAGs may encode the same set…

Methodology · Statistics 2021-02-15 Federico Castelletti , Stefano Peluso

We give a selective review of some recent developments in causal inference, intended for researchers who are not familiar with graphical models and causality, and with a focus on methods that are applicable to large data sets. We mainly…

Methodology · Statistics 2015-06-26 Marloes H. Maathuis , Preetam Nandy

This paper explores the role of Directed Acyclic Graphs (DAGs) as a representation of conditional independence relationships. We show that DAGs offer polynomially sound and complete inference mechanisms for inferring conditional…

Artificial Intelligence · Computer Science 2013-04-10 Dan Geiger , Judea Pearl

We propose a method to infer causal structures containing both discrete and continuous variables. The idea is to select causal hypotheses for which the conditional density of every variable, given its causes, becomes smooth. We define a…

Machine Learning · Statistics 2009-10-30 Dominik Janzing , Xiaohai Sun , Bernhard Schoelkopf

Causal inference methods for observational data are increasingly recognized as a valuable complement to randomized clinical trials (RCTs). They can, under strong assumptions, emulate RCTs or help refine their focus. Our approach to causal…

Methodology · Statistics 2024-08-14 Carlo Berzuini , Davide Luciani , Hiren C. Patel

In multivariate time series analysis, understanding the underlying causal relationships among variables is often of interest for various applications. Directed acyclic graphs (DAGs) provide a powerful framework for representing causal…

Methodology · Statistics 2025-07-30 Arkaprava Roy , Anindya Roy , Subhashis Ghosal

We consider the problem of inferring the causal structure from observational data, especially when the structure is sparse. This type of problem is usually formulated as an inference of a directed acyclic graph (DAG) model. The linear…

Machine Learning · Statistics 2025-08-21 Kazuharu Harada , Hironori Fujisawa

We focus on the extension of bivariate causal learning methods into multivariate problem settings in a systematic manner via a novel framework. It is purposive to augment the scale to which bivariate causal discovery approaches can be…

Methodology · Statistics 2023-05-29 Hongyi Chen , Maurits Kaptein

Graphical models can represent a multivariate distribution in a convenient and accessible form as a graph. Causal models can be viewed as a special class of graphical models that not only represent the distribution of the observed system…

Methodology · Statistics 2017-06-29 Christina Heinze-Deml , Marloes H. Maathuis , Nicolai Meinshausen

Quantifying causal effects of exposures on outcomes, such as a treatment and a disease respectively, is a crucial issue in medical science for the administration of effective therapies. Importantly, any related causal analysis should…

Methodology · Statistics 2024-09-04 Federico Castelletti , Laura Ferrini

This article surveys the variety of ways in which a directed acyclic graph (DAG) can be used to represent a problem of probabilistic causality. For each of these we describe the relevant formal or informal semantics governing that…

Statistics Theory · Mathematics 2024-02-16 Philip Dawid

We assume that we have observational data generated from an unknown underlying directed acyclic graph (DAG) model. A DAG is typically not identifiable from observational data, but it is possible to consistently estimate the equivalence…

Methodology · Statistics 2009-09-02 Marloes H. Maathuis , Markus Kalisch , Peter Bühlmann

This paper concerns the assessment of direct causal effects from a combination of: (i) non-experimental data, and (ii) qualitative domain knowledge. Domain knowledge is encoded in the form of a directed acyclic graph (DAG), in which all…

Artificial Intelligence · Computer Science 2013-01-07 Carlos Brito , Judea Pearl

Background: Diagnostic test accuracy (DTA) studies, like etiological studies, are susceptible to various biases including reference standard error bias, partial verification bias, spectrum effect, confounding, and bias from misassumption of…

Methodology · Statistics 2026-01-21 Yang Lu , Nandini Dendukuri

Learning the structure of causal directed acyclic graphs (DAGs) is useful in many areas of machine learning and artificial intelligence, with wide applications. However, in the high-dimensional setting, it is challenging to obtain good…

Machine Learning · Statistics 2024-05-27 Stephen Smith , Qing Zhou

Recent work on causal abstraction, in particular graphical approaches focusing on causal structure between clusters of variables, aims to summarize a high-dimensional causal structure in terms of a low-dimensional one. Existing methods for…

Machine Learning · Statistics 2026-05-12 Francisco Madaleno , Francisco C Pereira , Alex Markham

Choices based on observational data depend on beliefs about which correlations reflect causality. An agent predicts the consequence of available actions using a dataset and her subjective beliefs about causality represented by a directed…

Theoretical Economics · Economics 2025-03-21 Andrew Ellis , Heidi Christina Thysen

We consider identifying a conditional causal effect when a graph is known up to a maximally oriented partially directed acyclic graph (MPDAG). An MPDAG represents an equivalence class of graphs that is restricted by background knowledge and…

Artificial Intelligence · Computer Science 2025-07-22 Sara LaPlante , Emilija Perković

Despite several advances in recent years, learning causal structures represented by directed acyclic graphs (DAGs) remains a challenging task in high dimensional settings when the graphs to be learned are not sparse. In this paper, we…

Machine Learning · Computer Science 2023-05-16 Zhuangyan Fang , Shengyu Zhu , Jiji Zhang , Yue Liu , Zhitang Chen , Yangbo He