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Background: There is increasing interest in approaches for analyzing the effect of exposure mixtures on health. A key issue is how to simultaneously analyze often highly collinear components of the mixture, which can create problems such as…

Methodology · Statistics 2020-07-06 Thomas F. Webster , Marc G. Weisskopf

The ultimate goal of most scientific studies is to understand the underlying causal mechanism between the involved variables. Structural causal models (SCMs) are widely used to represent such causal mechanisms. Given an SCM, causal queries…

Machine Learning · Statistics 2025-03-21 Beate Sick , Oliver Dürr

Causal representation learning aims to recover the latent causal variables and their causal relations, typically represented by directed acyclic graphs (DAGs), from low-level observations such as image pixels. A prevailing line of research…

Machine Learning · Computer Science 2026-04-28 Ignavier Ng , Shaoan Xie , Xinshuai Dong , Peter Spirtes , Kun Zhang

We consider the problem of identifying a conditional causal effect through covariate adjustment. We focus on the setting where the causal graph is known up to one of two types of graphs: a maximally oriented partially directed acyclic graph…

Methodology · Statistics 2024-03-13 Sara LaPlante , Emilija Perković

Directed acyclic graphical models (DAGs) are often used to describe common structural properties in a family of probability distributions. This paper addresses the question of classifying DAGs up to an isomorphism. By considering Gaussian…

Information Theory · Computer Science 2014-12-24 Hajir Roozbehani , Yury Polyanskiy

We consider the problem of learning the structure of a causal directed acyclic graph (DAG) model in the presence of latent variables. We define latent factor causal models (LFCMs) as a restriction on causal DAG models with latent variables,…

Methodology · Statistics 2022-07-06 Chandler Squires , Annie Yun , Eshaan Nichani , Raj Agrawal , Caroline Uhler

Precise knowledge of causal directed acyclic graphs (DAGs) is assumed for standard approaches towards valid adjustment set selection for unbiased estimation, but in practice, the DAG is often inferred from data or expert knowledge,…

Statistics Theory · Mathematics 2025-11-14 Zhongyi Hu , Stéphanie van der Pas

Structural learning of directed acyclic graphs (DAGs) or Bayesian networks has been studied extensively under the assumption that data are independent. We propose a new Gaussian DAG model for dependent data which assumes the observations…

Machine Learning · Statistics 2021-07-30 Hangjian Li , Oscar Hernan Madrid Padilla , Qing Zhou

Directed Acyclic Graphs (DAGs) provide a powerful framework to model causal relationships among variables in multivariate settings; in addition, through the do-calculus theory, they allow for the identification and estimation of causal…

Machine Learning · Statistics 2022-01-31 Federico Castelletti , Alessandro Mascaro

We propose a novel score-based approach to learning a directed acyclic graph (DAG) from observational data. We adapt a recently proposed continuous constrained optimization formulation to allow for nonlinear relationships between variables…

Machine Learning · Computer Science 2020-02-19 Sébastien Lachapelle , Philippe Brouillard , Tristan Deleu , Simon Lacoste-Julien

Directed Acyclic Graphical (DAG) models efficiently formulate causal relationships in complex systems. Traditional DAGs assume nodes to be scalar variables, characterizing complex systems under a facile and oversimplified form. This paper…

Methodology · Statistics 2024-04-23 Tian Lan , Ziyue Li , Junpeng Lin , Zhishuai Li , Lei Bai , Man Li , Fugee Tsung , Rui Zhao , Chen Zhang

Causal discovery aims to infer causal relationships among variables from observational data, typically represented by a directed acyclic graph (DAG). Most existing methods assume independent and identically distributed observations, an…

Methodology · Statistics 2026-03-27 Alex Chen , Qing Zhou

Graphical models based on Directed Acyclic Graphs (DAGs) are widely used to answer causal questions across a variety of scientific and social disciplines. However, observational data alone cannot distinguish in general between DAGs…

Methodology · Statistics 2022-06-03 Federico Castelletti , Guido Consonni

It is known that from purely observational data, a causal DAG is identifiable only up to its Markov equivalence class, and for many ground truth DAGs, the direction of a large portion of the edges will be remained unidentified. The golden…

Machine Learning · Computer Science 2019-10-15 AmirEmad Ghassami , Saber Salehkaleybar , Negar Kiyavash

Probabilistic graphical models are a fundamental tool in statistics, machine learning, signal processing, and control. When such a model is defined on a directed acyclic graph (DAG), one can assign a partial ordering to the events occurring…

Information Theory · Computer Science 2011-10-05 Maxim Raginsky

Understanding causal relationships in multivariate time series is essential for predicting and controlling dynamic systems in fields like economics, neuroscience, and climate science. However, existing causal discovery methods often assume…

Machine Learning · Computer Science 2025-02-20 Abdellah Rahmani , Pascal Frossard

Estimating the structure of directed acyclic graphs (DAGs) of features (variables) plays a vital role in revealing the latent data generation process and providing causal insights in various applications. Although there have been many…

Machine Learning · Computer Science 2024-03-06 Shaohua Fan , Shuyang Zhang , Xiao Wang , Chuan Shi

Mainly motivated by the problem of modelling directional dependence relationships for multivariate count data in high-dimensional settings, we present a new algorithm, called learnDAG, for learning the structure of directed acyclic graphs…

Methodology · Statistics 2024-06-10 Thi Kim Hue Nguyen , Monica Chiogna , Davide Risso

New biological assays like Perturb-seq link highly parallel CRISPR interventions to a high-dimensional transcriptomic readout, providing insight into gene regulatory networks. Causal gene regulatory networks can be represented by directed…

Machine Learning · Statistics 2024-02-22 Albert Xue , Jingyou Rao , Sriram Sankararaman , Harold Pimentel

We study a family of regularized score-based estimators for learning the structure of a directed acyclic graph (DAG) for a multivariate normal distribution from high-dimensional data with $p\gg n$. Our main results establish support…

Statistics Theory · Mathematics 2017-10-03 Bryon Aragam , Arash A. Amini , Qing Zhou
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