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We design and demonstrate a monolithically integrated silicon photonic multichannel optical hybrid for versatile broadband coherent reception, addressing the critical limitations of current wavelength multiplexed systems in scalability and…

We present an approach to fabrication and packaging of integrated photonic devices that utilizes waveguide and detector layers deposited at near-ambient temperature. All lithography is performed with a 365 nm i-line stepper, facilitating…

We introduce and experimentally characterize a general purpose device for signal processing in circuit quantum electrodynamics systems. The device is a broadband two-port microwave circuit element with three modes of operation: it can…

Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Piumi Sandarenu , Julia Chen , Iveta Slapetova , Lois Browne , Peter H. Graham , Alexander Swarbrick , Ewan K. A. Millar , Yang Song , Erik Meijering

More than 10,000 photomultiplier tubes (PMTs) with a diameter of 80 mm will be installed in multi-PMT Digital Optical Modules (mDOMs) of the IceCube Upgrade. These have been tested and pre-calibrated at two sites. A throughput of more than…

Instrumentation and Methods for Astrophysics · Physics 2024-06-21 R. Abbasi , M. Ackermann , J. Adams , S. K. Agarwalla , J. A. Aguilar , M. Ahlers , J. M. Alameddine , N. M. Amin , K. Andeen , C. Argüelles , Y. Ashida , S. Athanasiadou , L. Ausborm , S. N. Axani , X. Bai , A. Balagopal V. , M. Baricevic , S. W. Barwick , S. Bash , V. Basu , R. Bay , J. J. Beatty , J. Becker Tjus , J. Beise , C. Bellenghi , C. Benning , S. BenZvi , D. Berley , E. Bernardini , D. Z. Besson , E. Blaufuss , L. Bloom , S. Blot , F. Bontempo , J. Y. Book Motzkin , C. Boscolo Meneguolo , S. Böser , O. Botner , J. Böttcher , J. Braun , B. Brinson , J. Brostean-Kaiser , L. Brusa , R. T. Burley , D. Butterfield , M. A. Campana , I. Caracas , K. Carloni , J. Carpio , S. Chattopadhyay , N. Chau , Z. Chen , D. Chirkin , S. Choi , B. A. Clark , A. Coleman , G. H. Collin , A. Connolly , J. M. Conrad , P. Coppin , R. Corley , P. Correa , D. F. Cowen , P. Dave , C. De Clercq , J. J. DeLaunay , D. Delgado , S. Deng , A. Desai , P. Desiati , K. D. de Vries , G. de Wasseige , T. DeYoung , A. Diaz , J. C. Díaz-Vélez , P. Dierichs , M. Dittmer , A. Domi , L. Draper , H. Dujmovic , K. Dutta , M. A. DuVernois , T. Ehrhardt , L. Eidenschink , A. Eimer , P. Eller , E. Ellinger , S. El Mentawi , D. Elsässer , R. Engel , H. Erpenbeck , J. Evans , P. A. Evenson , K. L. Fan , K. Fang , K. Farrag , A. R. Fazely , A. Fedynitch , N. Feigl , S. Fiedlschuster , C. Finley , L. Fischer , D. Fox , A. Franckowiak , S. Fukami , P. Fürst , J. Gallagher , E. Ganster , A. Garcia , M. Garcia , G. Garg , E. Genton , L. Gerhardt , A. Ghadimi , C. Girard-Carillo , C. Glaser , T. Glüsenkamp , J. G. Gonzalez , S. Goswami , A. Granados , D. Grant , S. J. Gray , O. Gries , S. Griffin , S. Griswold , K. M. Groth , C. Günther , P. Gutjahr , C. Ha , C. Haack , A. Hallgren , L. Halve , F. Halzen , H. Hamdaoui , M. Ha Minh , M. Handt , K. Hanson , J. Hardin , A. A. Harnisch , P. Hatch , A. Haungs , J. Häußler , K. Helbing , J. Hellrung , J. Hermannsgabner , L. Heuermann , N. Heyer , S. Hickford , A. Hidvegi , C. Hill , G. C. Hill , K. D. Hoffman , S. Hori , K. Hoshina , M. Hostert , W. Hou , T. Huber , K. Hultqvist , M. Hünnefeld , R. Hussain , K. Hymon , A. Ishihara , W. Iwakiri , M. Jacquart , O. Janik , M. Jansson , G. S. Japaridze , M. Jeong , M. Jin , B. J. P. Jones , R. Joppe , N. Kamp , D. Kang , W. Kang , X. Kang , A. Kappes , D. Kappesser , L. Kardum , T. Karg , M. Karl , A. Karle , A. Katil , U. Katz , M. Kauer , J. L. Kelley , M. Khanal , A. Khatee Zathul , A. Kheirandish , J. Kiryluk , A. Kochocki , R. Koirala , H. Kolanoski , T. Kontrimas , L. Köpke , C. Kopper , D. J. Koskinen , M. Kossatz , P. Koundal , M. Kovacevich , M. Kowalski , T. Kozynets , J. Krishnamoorthi , K. Kruiswijk , E. Krupczak , A. Kumar , E. Kun , N. Kurahashi , N. Lad , C. Lagunas Gualda , M. Lamoureux , M. J. Larson , S. Latseva , F. Lauber , J. P. Lazar , J. W. Lee , K. Leonard DeHolton , A. Leszczyńska , J. Liao , M. Lincetto , Y. T. Liu , M. Liubarska , E. Lohfink , C. Love , C. J. Lozano Mariscal , L. Lu , F. Lucarelli , W. Luszczak , Y. Lyu , J. Madsen , E. Magnus , K. B. M. Mahn , Y. Makino , E. Manao , S. Mancina , W. Marie Sainte , I. C. Mariş , S. Marka , Z. Marka , M. Marsee , I. Martinez-Soler , R. Maruyama , F. Mayhew , F. McNally , J. V. Mead , K. Meagher , S. Mechbal , A. Medina , M. Meier , Y. Merckx , L. Merten , J. Micallef , J. Mitchell , T. Montaruli , R. W. Moore , Y. Morii , R. Morse , M. Moulai , T. Mukherjee , R. Naab , R. Nagai , M. Nakos , U. Naumann , J. Necker , A. Negi , L. Neste , M. Neumann , H. Niederhausen , M. U. Nisa , K. Noda , A. Noell , A. Novikov , A. Obertacke Pollmann , V. O'Dell , B. Oeyen , A. Olivas , R. Orsoe , J. Osborn , E. O'Sullivan , H. Pandya , N. Park , G. K. Parker , E. N. Paudel , L. Paul , C. Pérez de los Heros , T. Pernice , J. Peterson , S. Philippen , A. Pizzuto , M. Plum , A. Pontén , Y. Popovych , M. Prado Rodriguez , B. Pries , R. Procter-Murphy , G. T. Przybylski , C. Raab , J. Rack-Helleis , M. Ravn , K. Rawlins , Z. Rechav , A. Rehman , P. Reichherzer , E. Resconi , S. Reusch , W. Rhode , B. Riedel , A. Rifaie , E. J. Roberts , S. Robertson , S. Rodan , G. Roellinghoff , M. Rongen , A. Rosted , C. Rott , T. Ruhe , L. Ruohan , D. Ryckbosch , I. Safa , J. Saffer , D. Salazar-Gallegos , P. Sampathkumar , A. Sandrock , M. Santander , S. Sarkar , S. Sarkar , J. Savelberg , P. Savina , P. Schaile , M. Schaufel , H. Schieler , S. Schindler , B. Schlüter , F. Schlüter , N. Schmeisser , T. Schmidt , J. Schneider , F. G. Schröder , L. Schumacher , S. Sclafani , D. Seckel , M. Seikh , M. Seo , S. Seunarine , P. Sevle Myhr , R. Shah , S. Shefali , N. Shimizu , M. Silva , B. Skrzypek , B. Smithers , R. Snihur , J. Soedingrekso , A. Søgaard , D. Soldin , P. Soldin , G. Sommani , C. Spannfellner , G. M. Spiczak , C. Spiering , M. Stamatikos , T. Stanev , T. Stezelberger , T. Stürwald , T. Stuttard , K. H. Sulanke , G. W. Sullivan , I. Taboada , S. Ter-Antonyan , A. Terliuk , M. Thiesmeyer , W. G. Thompson , J. Thwaites , S. Tilav , K. Tollefson , C. Tönnis , S. Toscano , D. Tosi , A. Trettin , R. Turcotte , J. P. Twagirayezu , M. A. Unland Elorrieta , A. K. Upadhyay , K. Upshaw , A. Vaidyanathan , N. Valtonen-Mattila , J. Vandenbroucke , N. van Eijndhoven , D. Vannerom , J. van Santen , J. Vara , J. Veitch-Michaelis , M. Venugopal , M. Vereecken , S. Verpoest , D. Veske , A. Vijai , C. Walck , A. Wang , C. Weaver , P. Weigel , A. Weindl , J. Weldert , A. Y. Wen , C. Wendt , J. Werthebach , M. Weyrauch , N. Whitehorn , C. H. Wiebusch , D. R. Williams , L. Witthaus , A. Wolf , M. Wolf , G. Wrede , X. W. Xu , J. P. Yanez , E. Yildizci , S. Yoshida , R. Young , S. Yu , T. Yuan , Z. Zhang , P. Zhelnin , P. Zilberman , M. Zimmerman

This report introduces a novel optofluidic platform based on piezo-MEMS technology, capable of identifying subtle variations in the fluid concentration. The system utilizes piezoelectric micromachined ultrasound transducers (PMUTs) as…

Due to the global water crisis there is a strong need for real-time water quality monitoring with high temporal and spatial resolution. This paper presents an economical multiparameter water quality monitoring system for continuous…

Significance: For the first time to our knowledge, a millifluidic device has been designed to observe the effects of blue-light irradiation in Pseudomonas aeruginosa PA01 bacterial biofilm. Approach: A bacterial biofilm is formed under…

Biological Physics · Physics 2023-11-30 Nidia Maldonado Carmona , Murielle Balthazar , Joanne L Fothergill , Nelly Henry

We suggest a low cost, non invasive healthcare system that measures haemoglobin levels in patients and can be used as a preliminary diagnostic test for anaemia. A combination of image processing, machine learning and deep learning…

Machine Learning · Computer Science 2020-12-01 Sarah , S. Sidhartha Narayan , Irfaan Arif , Hrithwik Shalu , Juned Kadiwala

We present a unique, multitask dataset comprising 143 drug and drug candidate molecules, each evaluated on in vitro, parallel artificial-membrane permeability assays (PAMPA) using six different model membranes. Using this resource, we…

Machine Learning · Computer Science 2026-05-04 Andrs Formanek , Anna Vincze , Richrd Bicsak , Yves Moreau , Gyorgy T. Balogh , Adam Arany

Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over…

Biological Physics · Physics 2025-02-18 Shobhit Das , Shilpi Pandey , Oliver Hayden

We used a microfluidic platform to address the problems of obtaining diffraction quality crystals and crystal handling during transfer to the X-ray diffractometer. We optimize crystallization conditions of a pharmaceutical protein and…

We propose a portable cartridge based lab-on-a-chip platform. The main sensing mechanism uses high frequency acoustic waves. Feasibility of two different transducers has been investigated for biological measurements. We used zincoxide (ZnO)…

Medical Physics · Physics 2017-10-17 Seyedfakhreddin Nabavi

In water monitoring, environmental analysis, cell culture stability, and biomedical applications, precise pH control is demanded. Traditional methods like pH strips and meters have limitations: pH strips lack precision, while…

With the growing interest in graphene field-effect transistors (GFETs) for biosensing applications, there is a strong demand for strategies enabling flexible and multiplexed biofunctionalization, as well as highly parallel, real-time…

Droplet-based high throughput biomolecular screening and combinatorial synthesis entail a viable indexing strategy to be developed for the identification of each micro-reactor. Here, we propose a novel indexing scheme based on the…

Soft Condensed Matter · Physics 2018-11-29 Wenya Song , Gungun Lin , Jin Ge , Jurgen Fassbender , Denys Makarov

This study presents a novel thermocouple instrument designed for precise temperature monitoring within biological tissues and cells, addressing a significant gap in biological research. Constructed on a Silicon-On-Insulator (SOI) substrate,…

In this work, a miniaturized, automated, and cost-effective ELISA device is designed and implemented, without the utilization of conventional techniques such as pipetting or microfluidic valve technologies. The device has dimensions of 24…

Medical Physics · Physics 2025-04-01 Majid Aalizadeh , Shuo Yang , Suchithra Guntur , Vaishnavi Potluri , Girish Kulkarni , Xudong Fan
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